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Deferiprone Related Arthropathy in 11-Year-Old Boy with Hereditary Spherocytosis

Seo YK, Han JK, Suh WS, Park KB

Regular transfusion therapy in children with intractable hematologic disorder results in hemosiderosis. It causes several organ damages such as liver, heart, and endocrine system and increases risk of infection. Thus,...
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Effects of 3,3′,4,4′,5-pentachlorobiphenyl on human Kv1.3 and Kv1.5 channels

Kim JH, Hwang S, Park SI, Jo SH

Among the environmental chemicals that may be able to disrupt the endocrine systems of animals and humans are polychlorinated biphenyls (PCBs), a chemical class of considerable concern. PCB consists of...
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Evaluation and management of amenorrhea related to congenital sex hormonal disorders

Yoon JY, Cheon CK

Primary amenorrhea is a symptom with a substantial list of underlying etiologies which presents in adolescence, although some conditions are diagnosed in childhood. Primary amenorrhea is defined as not having...
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Understanding the molecular mechanisms of bisphenol A action in spermatozoa

Rahman MS, Pang MG

Bisphenol A (BPA) is an endocrine-disrupting chemical that is capable of interfering with the normal function of the endocrine system in the body. Exposure to this chemical from BPA-containing materials...
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Natural Killer Cells and Thyroid Diseases

Lee EK, Sunwoo JB

Abnormal production of thyroid hormone is one of the common endocrine disorders, and thyroid hormone production declines with age. The aging process also negatively affects the immune system. An interaction...
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Human Immunodeficiency Virus Infection and the Endocrine System

Zaid D, Greenman Y

In the current era of effective antiretroviral therapies (ARTs), human immunodeficiency virus (HIV) infection became a chronic disorder that requires long term follow-up. Among other medical issues, these patients may...
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Search for Novel Mutational Targets in Human Endocrine Diseases

Park SY, Seo MH, Lee S

The identification of disease-causing genetic variations is an important goal in the field of genetics. Advancements in genetic technology have changed scientific knowledge and made it possible to determine the...
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Chronic Functional Constipation

Shin JE, Park KS, Nam K

Constipation is a common functional problem of the digestive system and may occur secondary to diet, drugs, endocrine diseases, metabolic diseases, neurological diseases, psychiatric disorders, or gastrointestinal obstruction. When there...
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Epidemiological characteristics of HIV infected Korean: Korea HIV/AIDS Cohort Study

Choi Y, Choi BY, Kim SM, Kim SI, Kim J, Choi JY, Kim SW, Song JY, Kim YJ, Park DW, Kim HY, Choi HJ, Kee MK, Shin YH, Yoo M

OBJECTIVES: To manage evidence-based diseases, it is important to identify the characteristics of patients in each country. METHODS: The Korea HIV/AIDS Cohort Study seeks to identify the epidemiological characteristics of 1,442...
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Predictive Value of Endometrial Thickness for Anemia in Adolescent Girls with Abnormal Uterine Bleeding

Lee JS, Cho YH, Jeon IS

BACKGROUND: Immaturity of the endocrine system that controls the normal menstrual cycle frequently results in abnormal uterine bleeding (AUB) and elicits anemia in adolescent girls. This study was conducted to...
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Treatment with Phytoestrogens Reversed Triclosan and Bisphenol A-Induced Anti-Apoptosis in Breast Cancer Cells

Lee GA, Choi KC, Hwang KA

Triclosan (TCS) and bisphenol A (BPA) are endocrine-disrupting chemicals that interfere with the hormone or endocrine system and may cause cancer. Kaempferol (Kaem) and 3,3′-diindolylmethane (DIM) are phytoestrogens that play...
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Positive Effects of Bisphosphonates on Osteogenic Differentiation in Patient-Derived Mesenchymal Stem Cells for the Treatment of Osteoporosis

Cha M, Lee KM, Lee JH

BACKGROUND: Recent evidence from in vitro and in vivo studies indicates that bisphosphonates may promote osteoblastic bone formation and potently inhibit osteoclast activity. However, little is known about the potential...
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The Status and Distinct Characteristics of Endocrine Diseases in North Korean Articles Published between 2006 and 2015

Kim KJ, Ha S, Lee YH, Noh JH, Kim SG

BACKGROUND: Past decades of division have led to substantial differences in medical environments between South and North Korea. However, little is known about North Korea's medical status and research field,...
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Intraoperative Neural Monitoring in Thyroid Surgery: Role and Responsibility of Surgeon

Kim HY, Tufano RP, Chai YJ, Barczynski M, Makay O, Wu CW, Berber E, Sun H, Dionigi G, the Korean Intraoperative Neural Monitoring Society (KINMoS)

Surgeons who introduce intraoperative neural monitoring (IONM) or a new IONM accessory, or related procedure in their practice should have completed relevant surgical training, possess operating privileges in the affected...
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Childhood obesity and endocrine disrupting chemicals

Kim JT, Lee HK

The prevalence of obesity around the world has increased sharply. Strong evidence has emerged over the last decades that human exposure to numerous endocrine disrupting chemicals (EDCs) is the cause...
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What is fetal programming?: a lifetime health is under the control of in utero health

Kwon EJ, Kim YJ

The “Barker hypothesis” postulates that a number of organ structures and associated functions undergo programming during embryonic and fetal life, which determines the set point of physiological and metabolic responses...
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Clinical manifestations of Rathke’s cleft cysts and their natural progression during 2 years in children and adolescents

Jung JE, Jin J, Jung MK, Kwon A, Chae HW, Kim DH, Kim HS

PURPOSE: Rathke’s cleft cyst (RCC) is an asymptomatic benign lesion. With increased interest in pediatric endocrinology, the prevalence of RCCs in children is also increasing. However, the clinical relevance and...
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Diabetes and Endocrine Disease

Bae JC, Han JM

Impaired insulin secretion and insulin resistance are the two main mechanisms leading to type 2 diabetes mellitus. Insulin exerts multiple effects upon target cells, especially skeletal muscle, liver, and adipose...
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Successful Radiofrequency Ablation of Parathyroid Adenoma in an Older Patient with Primary Hyperparathyroidism

Soh MS, Lee SH, Choi YJ, Kim HJ, Kim DJ, Lee KW, Han SJ

Primary hyperparathyroidism is one of the most common endocrine diseases and is defined as the inappropriate overproduction of parathyroid hormone, resulting in hypercalcemia. It occurs mostly as a result of...
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Prognostic Impact of Progesterone Receptor Status in Chinese Estrogen Receptor Positive Invasive Breast Cancer Patients

Yao N, Song Z, Wang X, Yang S, Song H

PURPOSE: Estrogen receptor (ER) and progesterone receptor (PR) have been used as indicators of endocrine system status since the mid-1970s in the clinical management of breast cancer. The predictive role...
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