- Propylthiouracil, Perchlorate, and Thyroid-Stimulating Hormone Modulate High Concentrations of Iodide Instigated Mitochondrial Superoxide Production in the Thyroids of Metallothionein I/II Knockout Mice
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Duan Q, Wang T, Zhang N, Perera V, Liang X, Abeysekera IR, Yao X
- KMID: 2169710
- Endocrinol Metab.
- 2016 Mar;31(1):174-184.
- doi: 10.3803/EnM.2016.31.1.174
BACKGROUND: Increased oxidative stress has been suggested as one of the underlying mechanisms in iodide excess-induced thyroid disease. Metallothioneins (MTs) are regarded as scavengers of reactive oxygen species (ROS) in... -
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- Long Noncoding RNA HEIH Promotes Colorectal Cancer Tumorigenesis via Counteracting miR-939-Mediated Transcriptional Repression of Bcl-xL
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Cui C, Zhai D, Cai L, Duan Q, Xie L, Yu J
- KMID: 2417888
- Cancer Res Treat.
- 2018 Jul;50(3):992-1008.
- doi: 10.4143/crt.2017.226
PURPOSE: Studies have found that long noncoding RNA HEIH (lncRNA-HEIH) is upregulated and facilitates hepatocellular carcinoma tumor growth. However, its clinical significances, roles, and action mechanism in colorectal cancer (CRC)... -
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