- The Role of NMDA Receptor Antagonists in Nicotine Tolerance, Sensitization, and Physical Dependence: A Preclinical Review
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Jain R, Mukherjee , Balhara YP
- KMID: 1084488
- Yonsei Med J.
- 2008 Apr;49(2):175-188.
- doi: 10.3349/ymj.2008.49.2.175
Nicotine, the primary psychoactive component of tobacco products, produces diverse neurophysiological, motivational, and behavioral effects through several brain regions and neurochemical pathways. Various neurotransmitter systems have been explored to understand... -
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- Intrathecal Lamotrigine Attenuates Antinociceptive Morphine Tolerance and Suppresses Spinal Glial Cell Activation in Morphine-Tolerant Rats
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Jun IG, Kim SH, Yoon YI, Park JY
- KMID: 1429208
- J Korean Med Sci.
- 2013 Feb;28(2):300-307.
- doi: 10.3346/jkms.2013.28.2.300
Glial cells play a critical role in morphine tolerance, resulting from repeated administration of morphine. Both the development and the expression of tolerance are suppressed by the analgesic lamotrigine. This... -
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- Gene Expression Profiling in C57BL/6 Mice Treated with the Anorectic Drugs Sibutramine and Phendimetrazine and Their Mechanistic Implications
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Ko MJ, Choi HS, Ahn JI, Kim SY, Jeong HS, Chung HJ
- KMID: 2166406
- Genomics Inform.
- 2008 Sep;6(3):117-125.
Recently, obesity has become a worldwide public health concern and the use of anorectic drugs has drastically increased. In this study, sibutramine and phendimetrazine, representative marketed anorectics, were repeatedly administered... -
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- Diagnosis and Management of Immediate Hypersensitivity Reactions to Cephalosporins
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Kim MH, Lee JM
- KMID: 2260170
- Allergy Asthma Immunol Res.
- 2014 Nov;6(6):485-495.
- doi: 10.4168/aair.2014.6.6.485
Cephalosporins can cause a range of hypersensitivity reactions, including IgE-mediated, immediate reactions. Cephalosporin allergy has been reported with use of a specific cephalosporin, as a cross-reaction between different cephalosporins or... -
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- Opioid-induced hyperalgesia
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Lee H
- KMID: 2194833
- J Korean Med Assoc.
- 2014 Jan;57(1):41-46.
- doi: 10.5124/jkma.2014.57.1.41
Perioperative opioid-induced hyperalgesia (OIH) can be defined as the "increased perception of pain after opioid-based anesthesia and surgery" since hyperalgesia is defined as "increased pain from a stimulus that normally... -
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- Short Insulin Tolerance Test Can Determine the Effects of Thiazolidinediones Treatment in Type 2 Diabetes
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Lee MY, Koh JH, Nam SM, Jung PM, Sung JK, Kim SY, Shin JY, Shin YG, Chung CH
- KMID: 1782937
- Yonsei Med J.
- 2008 Dec;49(6):901-908.
- doi: 10.3349/ymj.2008.49.6.901
PURPOSE: The short insulin tolerance test is a simple and reliable method of estimating insulin sensitivity. This study was designed to compare the insulin sensitizing effects of thiazolidinediones (TZDs) on... -
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- Application of Multidetector-row CT for Pancreas Imaging
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Kim MJ
- KMID: 782775
- Korean J Gastroenterol.
- 2006 Oct;48(4):256-262.
Recent development of multidetector-row CT (MDCT) has improved the z-axis resolution of spiral CT and provided the isotropic imaging capability, which enables various postprocessing technique without degradating the quality of... -
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- Effective Titration of Risperidone in Patients with Schizophrenia: Open Multicenter Randomized Comparative 8 Weeks Study
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Lee HS, Kim CH, Kim YH, Yoon DJ, Lee MS, Suh HS, Koo MS, The Multicenter Clinical Trial Group
- KMID: 2037063
- Korean J Psychopharmacol.
- 2002 Dec;13(4):276-288.
OBJECTIVE: Subsequent clinical experiences in risperidone treatment indicated that the initially recommended dose schedule resulted in too rapid increment of doses to the maintenance dose. The goal of this study... -
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- Agomelatine versus Sertraline: An Observational, Open-labeled and 12 Weeks Follow-up Study on Efficacy and Tolerability
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Akpınar E, Cerit C, Talas A, Tural U
- KMID: 2356159
- Clin Psychopharmacol Neurosci.
- 2016 Nov;14(4):351-356.
- doi: 10.9758/cpn.2016.14.4.351
OBJECTIVE: In this open-labeled, 12 weeks follow-up study, we aimed to compare the efficacy and tolerability of agomelatine with sertraline. METHODS: The outpatients of adult psychiatry clinic who have a new... -
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- Expression of Heat Shock Protein 27 in Prostate Cancer Cell Lines According to the Extent of Malignancy and Doxazosin Treatment
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Lee SW, Lee JW, Chung JH, Jo JK
- KMID: 2320822
- World J Mens Health.
- 2013 Dec;31(3):247-253.
PURPOSE: Heat shock protein 27 (HSP27) is known as the material that plays a role in apoptosis control in tumor and cell protection including the immune response, drug tolerance, and... -
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- A Case of Transmesocolic Hernia in Elderly Person without a History of Operation
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Park HS, Kim JI, Kim MS, Kim SS, Cho SH, Park SH, Han JY, Kim JK
- KMID: 782780
- Korean J Gastroenterol.
- 2006 Oct;48(4):286-289.
Internal hernia is defined as the herniation of viscera through an anatomic or pathologic opening within the boundaries of peritoneal cavity. Transmesocolic hernia, a subtype of internal hernia, has a... -
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- How Should Azathioprine Be Dosed in Crohn's Disease? A Novel Strategy of Maximum Dose-titration Based on the Lower Limit of Leukocyte Count and Tolerability
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Lim CS, Moon W, Park SJ, Park MI, Choi JM, Yoo JH, Kim JB, Lee JS
- KMID: 1775748
- Korean J Gastroenterol.
- 2013 Aug;62(2):111-116.
- doi: 10.4166/kjg.2013.62.2.111
BACKGROUND/AIMS: Although general guidelines have suggested weight-based dosing of azathioprine (AZA, 2.5 mg/kg/day) for Crohn's disease (CD), a substantial number of patients develop bone marrow suppression. The aim of this... -
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- ESHAP Salvage Therapy for Relapsed or Refractory Non-Hodgkin's Lymphoma
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Choi CW, Paek CW, Seo JH, Kim BS, Shin SW, Kim YH, Kim JS
- KMID: 1127252
- J Korean Med Sci.
- 2002 Oct;17(5):621-624.
- doi: 10.3346/jkms.2002.17.5.621
The ESHAP regimen, a combination of the chemotherapeutic drugs etoposide, methylprednisolone (solumedrol), high-dose cytarabine (ara-C), and cisplatin, has been shown to be active against refractory or relapsed non-Hodgkin's lymphoma... -
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- Evidence-Based, Pharmacological Treatment Guideline for Depression in Korea, Revised Edition
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Won E, Park SC, Han KM, Sung SH, Lee HY, Paik JW, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Hwang TY, Oh KS, Hahn SW, Park YC, Lee MS
- KMID: 1774451
- J Korean Med Sci.
- 2014 Apr;29(4):468-484.
- doi: 10.3346/jkms.2014.29.4.468
This paper aims to introduce, summarize, and emphasize the importance of the 'Evidence-Based, Pharmacological Treatment Guideline for Depression in Korea, Revised Edition'. The guideline broadly covers most aspects of the... -
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