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Pharmacokinetics and drug therapy in neonates

Cho HJ

Neonates include both full term and preterm infants up to 28 days of age. The heterogeneity and rapid physiologic change of neonates affect all aspects of pharmacokinetics such as absorption,...
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In vitro Evaluation of Antibiotic Lock Technique for the Treatment of Candida albicans, C. glabrata, and C. tropicalis Biofilms

Ko KS, Lee JY, Song JH, Peck KR

Candidaemia associated with intravascular catheter-associated infections is of great concern due to the resulting high morbidity and mortality. The antibiotic lock technique (ALT) was previously introduced to treat catheter-associated bacterial...
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Pericardial Approach for Cardiac Therapies: Old Practice With New Ideas

Han S, Hwang C

Treatment of cardiac disease via the epicardium fell under the domain of cardiac surgery due to the need for an open thoracotomy. Since an open thoracotomy is invasive in nature...
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Unilateral administration of a drug into the lung of a small animal

Cheong SH, Yang YI, Seo JY, Jun DH, Ko MJ, Cho KR, Lee SE, Kim YH, Lim SH, Lee JH, Lee KM

BACKGROUND: The selective unilateral administration of drugs into a single lung of a rat is difficult because of the small airway diameter. Therefore, a simple method for unilateral administration into...
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Management of Malaria in Thailand

Udomsak S, Srivicha K, Nanthaphorn P, Sornchai L

The purpose of treatment for uncomplicated malaria is to produce a radical cure using the combination of: artesunate (4 mg/kg/day) plus mefloquine (8 mg/kg day) for 3 days; a fixed...
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Fate of Transplanted Bone Marrow Derived Mesenchymal Stem Cells Following Spinal Cord Injury in Rats by Transplantation Routes

Kang ES, Ha KY, Kim YH

This research was performed to investigate the differences of the transplanted cells' survival and differentiation, and its efficacy according to the delivery routes following spinal cord injury. Allogenic mesenchymal stem...
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The Effects of Menopausal Hormone Therapy on Serum Level of C-reactive Protein in Postmenopausal Korean Women

Shin W, Kim SE, Lee JY, Seo JW, Hyun HS, Suh JH, Choi D, Yoon BK

OBJECTIVES: Inflammation is a major mechanism underlying coronary heart disease (CHD) and C-reactive protein (CRP) is a marker of inflammation. When administered soon after menopause, menopausal hormone therapy (MHT) prevents...
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Effect of intratesticular injection of xylazine/ketamine combination on canine castration

Kim JK, Jeong SM, Yi NY, Jeong MB, Lee ES, Nam TC, Seo KM

  • KMID: 1120072
  • J Vet Sci.
  • 2004 Jun;5(2):151-155.
This study was performed to compare the effect of intratesticular (IT) injection of xylazine/ketamine combination for canine castration with those of intramuscular (IM) or intravenous (IV) injection. Xylazine and ketamine...
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Intratracheal Administration of Endotoxin Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats

Shim JW, Chang YS, Park WS

  • KMID: 2396098
  • Yonsei Med J.
  • 2008 Feb;49(1):144-150.
PURPOSE: This study was undertaken to determine the effects of intratracheal administration of endotoxin on hyperoxia-induced lung injury in neonatal rats. MATERIALS AND METHODS: Newborn Sprague Dawley rat pups were...
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Effects of Hormone Therapy on Serum Lipid Levels in Postmenopausal Korean Women

Lee JY, Hyun HS, Park HG, Seo JH, Lee EY, Lee JS, Lee DY, Choi DS, Yoon BK

OBJECTIVES: This study was conducted to examine the effects of hormone therapy on serum lipid levels in postmenopausal Korean women. METHODS: This retrospective cohort study included 154 healthy postmenopausal Korean women....
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Trends in the Use of Chemotherapy before and after Radical Cystectomy in Patients with Muscle-invasive Bladder Cancer in Korea

Kim SH, Seo HK, Shin HC, Chang SJ, Yun S, Joo J, Ku JH, Kim HS, Jeon HG, Jeong BC, Jeong IG, Kang SH, Hong B, UCART (urothelial cancer-advanced research and treatment group in Korea) group

We investigated trends in perioperative chemotherapy use, and determined factors associated with neoadjuvant chemotherapy (NAC) and adjuvant chemotherapy (AC) use in Korean patients with muscle-invasive bladder cancer (MIBC). We recruited...
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