- Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells
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Kang DW, Min G, Park DY, Hong KW, Min DS
- KMID: 1104382
- Exp Mol Med.
- 2010 Aug;42(8):555-564.
- doi: 10.3858/emm.2010.42.8.056
Rebamipide a gastroprotective drug, is clinically used for the treatment of gastric ulcers and gastritis, but its actions on gastric cancer are not clearly understood. Phospholipase D (PLD) is overexpressed... -
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- Induction of Upregulation and Downregulation of the T-Cell Activation Marker CD98 in Patients Undergoing Contrast-Enhanced CT with Iodinated Non-Ionic Dimeric Contrast Medium
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Bohm I, Schild HH
- KMID: 1088679
- Korean J Radiol.
- 2009 Feb;10(1):58-62.
- doi: 10.3348/kjr.2009.10.1.58
OBJECTIVE: This study was designed to determine prospectively the expression of the multifunctional CD98 protein in peripheral white blood cells in patients receiving iodinated contrast media (CM) for a computed... -
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- Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib
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Kang D, Han Z, Oh GH, Joo Y, Choi HJ, Song JJ
- KMID: 2418924
- Yonsei Med J.
- 2017 Sep;58(5):899-909.
- doi: 10.3349/ymj.2017.58.5.899
PURPOSE: Sorafenib, a multikinase inhibitor, is the standard therapy for patients with advanced-stage hepatocellular carcinoma (HCC). However, resistance develops to the treatment, therefore, we tried to unravel the underlying mechanism... -
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- Transient downregulation of protein O-N-acetylglucosaminylation by treatment of high-dose nicotinamide in human cells
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Lee HI, Cho HJ, Han JA, Jang SY, Wang KM, Kang HT, Hwang ES
- KMID: 1052947
- Exp Mol Med.
- 2008 Apr;40(2):246-253.
- doi: 10.3858/emm.2008.40.2.246
Nicotinamide at millimolar concentrations affects cell survival in various conditions, and is being utilized therapeutically in many human diseases. However, the effect of an acute treatment of nicotinamide at such... -
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- Annexin A6 is highly abundant in monocytes of obese and type 2 diabetic individuals and is downregulated by adiponectin in vitro
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Stogbauer , Weigert J, Neumeier M, Wanninger , Sporrer D, Weber M, Schaffler , Enrich C, Wood P, Grewal T, Aslanidis , Buechler C
- KMID: 1058024
- Exp Mol Med.
- 2009 Jul;41(7):501-507.
- doi: 10.3858/emm.2009.41.7.055
Adiponectin stimulates cholesterol efflux in macrophages and low adiponectin may in part contribute to disturbed reverse cholesterol transport in type 2 diabetes. Monocytes express high levels of annexin A6 that... -
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