Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

172 results
Display

Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas

Kim J, Oh JH, Harlem H, Culler MD, Ku CR, Lee EJ

BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Role of Helix 8 in Dopamine Receptor Signaling

Yang HS, Sun N, Zhao X, Kim HR, Park HJ, Kim KM, Chung KY

G protein-coupled receptors (GPCRs) are membrane receptors whose agonist-induced dynamic conformational changes trigger heterotrimeric G protein activation, followed by GRK-mediated phosphorylation and arrestin-mediated desensitization. Cytosolic regions of GPCRs have been...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Combination of In Vivo [¹²³I]FP-CIT SPECT and Microdialysis Reveals an Antipsychotic Drug Haloperidol-induced Synaptic Dopamine Availability in the Rat Midbrain and Striatum

Park SH, Song YS, Moon BS, Lee BC, Park HS, Kim SE

Synaptic dopamine (DA) is mainly regulated by the presynaptic DA transporter (DAT). Single-photon emission computerized tomography (SPECT) with the DAT radiotracer [¹²³I]FP-CIT assesses changes in synaptic DA availability when endogenous...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Long-term Effects of Aripiprazole Treatment during Adolescence on Cognitive Function and Dopamine D2 Receptor Expression in Neurodevelopmentally Normal Rats

Choi HJ, Im SJ, Park HR, Park S, Kim CE, Ryu S

OBJECTIVE: This study aimed to investigate the long-term effects of aripiprazole treatment during adolescence on behavior, cognitive function, and dopamine D2 receptor (D2R) expression in adult rats. METHODS: Adolescent male Sprague-Dawley...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity

Gu SM, Kim SY, Lamichhane S, Hong JT, Yun J

Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine-induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Reduced Uptake on Dopamine Transporter Imaging by Methylphenidate

Ha J, Ko J, Song JT, Hong JY

No abstract available.
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Heterogeneous Patterns of Striatal Dopamine Loss in Patients with Young- versus Old-Onset Parkinson's Disease: Impact on Clinical Features

Chung SJ, Yoo HS, Lee YH, Lee PH, Sohn YH

OBJECTIVE: Ample evidence has suggested that age at onset of Parkinson's disease (PD) is associated with heterogeneous clinical features in individuals. We hypothesized that this may be attributed to different...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Nonmotor and Dopamine Transporter Change in REM Sleep Behavior Disorder by Olfactory Impairment

Lee JY, Yoon EJ, Kim YK, Shin CW, Nam H, Jeong JM, Kim HJ, Jeon B

OBJECTIVE: It is unclear whether the decline in dopamine transporters (DAT) differs among idiopathic rapid eye movement sleep behavior disorder (iRBD) patients with different levels of olfactory impairment. This study...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Delayed Treatment of Capsaicin Produces Partial Motor Recovery by Enhancing Dopamine Function in MPP⁺-lesioned Rats via Ciliary Neurotrophic Factor

Kim KI, Baek JY, Jeong JY, Nam JH, Park ES, Bok E, Shin WH, Chung YC, Jin BK

Transient receptor potential vanilloid subtype 1 (TRPV1) on astrocytes prevents ongoing degeneration of nigrostriatal dopamine (DA) neurons in MPP⁺-lesioned rats via ciliary neurotrophic factor (CNTF). The present study determined whether...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of Single-Nucleotide Polymorphisms on Decline of Dopamine Transporter Availability in Parkinson's Disease

Shin S, Kim K, Lee JM, Kim EJ, Kim SJ, Kim IJ, Pak K, Lee MJ

BACKGROUND AND PURPOSE: We aimed to determine the association between the annual changes in dopamine transporter (DAT) availability as measured by 123I-ioflupane (123I-FP-CIT) single-photon-emission computed tomography and single-nucleotide polymorphisms (SNPs)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Regional difference in spontaneous firing inhibition by GABA(A) and GABA(B) receptors in nigral dopamine neurons

Kim Y, Jang J, Kim HJ, Park MK

GABAergic control over dopamine (DA) neurons in the substantia nigra is crucial for determining firing rates and patterns. Although GABA activates both GABA(A) and GABA(B) receptors distributed throughout the somatodendritic...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Consolidation of a Learned Skill Correlates with Dopamine SPECT Uptake in Early Parkinson's Disease

Nicastro N, Manuel AL, Garibotto , Burkhard P, Schnider A

BACKGROUND AND PURPOSE: Basal ganglia play a pivotal role in procedural memory. However, the correlation between skill learning and striatal 123I-ioflupane uptake in Parkinson's disease (PD) has not been reported...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo

Bok E, Cho EJ, Chung ES, Shin WH, Jin BK

The present study investigated the effects of interleukin (IL)-4 on dopamine (DA) neurons in the substantia nigra (SN) in vivo of lipopolysaccharide (LPS)-treated rat. Tyrosine hydroxylase immunohistochemistry showed a significant...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of rs3910105 in the Synuclein Gene on Dopamine Transporter Availability in Healthy Subjects

Seo Y, Pak K, Nam HY, Seok JW, Lee MJ, Kim EJ, Lee JM, Kim SJ, Kim IJ

PURPOSE: The present study investigated associations between dopamine transporter (DAT) availability and α-synuclein levels in cerebrospinal fluid, as well as synuclein gene (SNCA) transcripts, and the effect of single nucleotide...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Ameliorative Effects of Ombuoside on Dopamine Biosynthesis in PC12 Cells

Davaasambuu U, Park KH, Park HJ, Choi HS, Lee CK, Hwang BY, Lee MK

This study investigated the effects of ombuoside, a flavonol glycoside, on dopamine biosynthesis in PC12 cells. Ombuoside at concentrations of 1, 5, and 10 µM increased intracellular dopamine levels at...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Berberine alleviates symptoms of anxiety by enhancing dopamine expression in rats with post-traumatic stress disorder

Lee B, Shim I, Lee H, Hahm DH

Post-traumatic stress disorder (PTSD) is a trauma-induced psychiatric disorder characterized by impaired fear extermination, hyperarousal, anxiety, depression, and amnesic symptoms that may involve the release of monoamines in the fear...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Abnormal Dopamine Transporter Positron Emission Tomography Image Caused by Lesion on Nigrostriatal Tract

Hong JY

No abstract available.
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Investigation into the Possible Genetic Role of Serotonin and Dopamine Transporters in Psychological Resilience

Cho SH, Chung JK, Bang YW, Joo EJ

OBJECTIVES: Psychological resilience is the ability to cope with stress. The genetic background behind psychological resilience is not much known. The serotonin transporter and dopamine transporter are implicated in stress...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
MPTP-induced vulnerability of dopamine neurons in A53T α-synuclein overexpressed mice with the potential involvement of DJ-1 downregulation

Lee S, Oh ST, Jeong HJ, Pak SC, Park HJ, Kim J, Cho HS, Jeon S

Familial Parkinson's disease (PD) has been linked to point mutations and duplication of the α-synuclein (α-syn) gene. Mutant α-syn expression increases the vulnerability of neurons to exogenous insults. In this...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Abnormal Sleep Delta Rhythm and Interregional Phase Synchrony in Patients with Restless Legs Syndrome and Their Reversal by Dopamine Agonist Treatment

Choi JW, Jeong MH, Her SJ, Lee BU, Cha KS, Jung KY, Kim KH

BACKGROUND AND PURPOSE: The purpose of this study was to characterize abnormal cortical activity during sleep in restless legs syndrome (RLS) patients and to determine the effects of treatment with...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr