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SNP genetic polymorphisms of MDR-1, CYP1A2 and CYPB11 genes in four canine breeds upon toxicological evaluation

Gagliardi , Llambi S, Arruga MV

The fields of pharmacogenetics and pharmacogenomics have become increasingly promising regarding the clinical application of genetic data to aid in prevention of adverse reactions. Specific screening tests can predict which...
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Post-mortem re-cloning of a transgenic red fluorescent protein dog

Hong SG, Koo OJ, Oh HJ, Park JE, Kim M, Kim GA, Park EJ, Jang G, Lee BC

Recently, the world's first transgenic dogs were produced by somatic cell nuclear transfer. However, cellular senescence is a major limiting factor for producing more advanced transgenic dogs. To overcome this...
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Population genetic study of 10 short tandem repeat loci from 600 domestic dogs in Korea

Moon SH, Jang YJ, Han MS, Cho MH

Dogs have long shared close relationships with many humans. Due to the large number of dogs in human populations, they are often involved in crimes. Occasionally, canine biological evidence such...
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Novel insertion mutation of ABCB1 gene in an ivermectin-sensitive Border Collie

Han JI, Son HW, Park SC, Na KJ

P-glycoprotein (P-gp) is encoded by the ABCB1 gene and acts as an efflux pump for xenobiotics. In the Border Collie, a nonsense mutation caused by a 4-base pair deletion in...
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Identification of differentially expressed genes in gauze-exposed omentum of dogs using differential display RT-PCR

Rahman MM, Kim Y, Byeon YE, Ryu HH, Kim WH, Rayhan MU, Kweon OK

Molecular mechanisms governing peritonitis caused by the presence of aseptic gauze have remained unclear. To identify the genes involved, sterile gauze-exposed omentum was collected at 0, 6, 12, 24, and...
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