- Thiol Disulfide Homeostasis in Schizophrenic Patients Using Atypical Antipsychotic Drugs
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Dogan HO, Ersan EE, Aydin H, Erdoğan S, Erşan S, Alişik M, Bakir S, Erel O, Koç D
- KMID: 2405232
- Clin Psychopharmacol Neurosci.
- 2018 Feb;16(1):39-45.
- doi: 10.9758/cpn.2018.16.1.39
OBJECTIVE: Schizophrenia is a severe, debilitating mental disorder characterized by behavioral abnormalities. Although several studies have investigated the role of oxidative stress and the effects of antipsychotic drugs on oxidative... -
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- Dynamic thiol/disulfide homeostasis as a novel indicator of oxidative stress in patients with urolithiasis
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Sonmez MG, Kozanhan B, Deniz CD, Iyisoy MS, Kilinc MT, Ecer G, Ozturk A, Neselioglu S, Erel O
- KMID: 2450543
- Investig Clin Urol.
- 2019 Jul;60(4):258-266.
- doi: 10.4111/icu.2019.60.4.258
PURPOSE: A dynamic thiol/disulfide balance is pivotal in organizing anti-oxidant defense, detoxification, apoptosis, and enzyme activities, as well as transcription and cellular signal-transfer mechanisms. The connection between urolithiasis and oxidant/antioxidant... -
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- Induction of apoptosis with diallyl disulfide in AGS gastric cancer cell line
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Lee JE, Lee RA, Kim KH, Lee JH
- KMID: 2096661
- J Korean Surg Soc.
- 2011 Aug;81(2):85-95.
- doi: 10.4174/jkss.2011.81.2.85
PURPOSE: Diallyl disulfide (DADS) is a major organosulfur compound derived from garlic. It has been reported that DADS is able to inhibit the proliferation of several tumor cells. In this... -
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- Psammaplin A is a natural prodrug that inhibits class I histone deacetylase
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Kim DH, Shin J, Kwon HJ
- KMID: 1103680
- Exp Mol Med.
- 2007 Feb;39(1):47-55.
Histone deacetylase (HDAC) has been highlighted as one of key players in tumorigenesis and angiogenesis. Recently, several derivatives of psammaplin (Psams) from a marine sponge have been known to inhibit... -
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- Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines
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Hong YS, Ham YA, Choi JH, Kim JG
- KMID: 755076
- Exp Mol Med.
- 2000 Sep;32(3):127-134.
Allyl sulfur compounds play a major role in the chemoprevention against carcinogenesis. The present study compared the antiproliferative effects of diallyl sulfide (DAS), diallyl disulfide (DADS) and garlic... -
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- Role of Ca(2+) in diallyI disulfide-induced apoptotic cell death of HCT-15 cells.
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Park EK, Kwon KB, Park KI, Park BH, Jhee EC
- KMID: 1380234
- Exp Mol Med.
- 2002 Jul;34(3):250-257.
Diallyl disulfide (DADS) induced apoptosis through the caspase-3 dependent pathway in leukemia cells was earlier reported from this laboratory. In this study, we investigated the involvement of Ca(2+) in DADS-induced... -
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- Structure-activity relationships of anti-HIV-1 peptides with disulfide linkage between D- and L-cysteine at positions i and i+3, respectively, derived from HIV-1 gp41 C-peptide
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Lee MK, Kim HK, Lee TY, Hahm KS, Kim KL
- KMID: 1105273
- Exp Mol Med.
- 2006 Feb;38(1):18-26.
The constrained alpha-helical structure of a C-peptide is useful for enhancing anti-HIV-1 activity. The i and i+3 positions in an alpha-helical structure are located close together, therefore D-Cys (dC) and... -
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