- 15-Deoxy-delta 12,14-ProstaglandinJ2 Regulates Dedifferentiation through Peroxisome Proliferator-Activated Receptor-gamma-Dependent Pathway but Not COX-2 Expression in Articular Chondrocytes
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Lee JH, Yu SM, Yoon EK, Lee WK, Jung JC, Kim SJ
- KMID: 1713299
- J Korean Med Sci.
- 2007 Oct;22(5):891-897.
- doi: 10.3346/jkms.2007.22.5.891
Peroxisome proliferator-activated receptors-gamma (PPAR-gamma) is critical for phenotype determination at early differentiation stages of mesenchymal cells, whereas its physiological role is unclear. Therefore, we investigated the role of 15-deoxy-delta 12,14-prostaglandinJ2... -
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- Anti-inflammatory effects of a Houttuynia cordata supercritical extract
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Shin S, Joo SS, Jeon JH, Park D, Jang MJ, Kim TO, Kim HK, Hwang BY, Kim KY, Kim YB
- KMID: 1093504
- J Vet Sci.
- 2010 Sep;11(3):273-275.
- doi: 10.4142/jvs.2010.11.3.273
Anti-inflammatory effects of Houttuynia cordata supercritical extract (HSE) were investigated in a carrageenan-air pouch model. HSE (200 mg/kg, oral) suppressed exudation and albumin leakage, as well as inflammatory cell infiltration.... -
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- beta-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macro phages by suppressing redox-based NF-kappaB activation
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Bai SK, Lee SJ, Na HJ, Ha KS, Han JA, Lee H, Kwon YG, Chung CK, Kim YM
- KMID: 1093467
- Exp Mol Med.
- 2005 Aug;37(4):323-334.
beta-Carotene has shown antioxidant and antiinflammatory activities; however, its molecular mechanism has not been clearly defined. We examined in vitro and in vivo regulatory function of beta-carotene on the production... -
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- Pulsed Electromagnetic Field Stimulates Cellular Proliferation in Human Intervertebral Disc Cells
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Lee HM, Kwon UH, Kim H, Kim HJ, Kim B, Park JO, Moon ES, Moon SH
- KMID: 1779646
- Yonsei Med J.
- 2010 Nov;51(6):954-959.
- doi: 10.3349/ymj.2010.51.6.954
PURPOSE: The purpose of this study is to investigate the mechanism of cellular proliferation of electromagnetic field (EMF) on human intervertebral disc (IVD) cells. MATERIALS AND METHODS: Human IVD cells... -
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- Dexamethasone differentiates NG108-15 cells through cyclooxygenase1 induction
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Kim HS, Song M, Kim E, Ryu SH, Suh PG
- KMID: 1094702
- Exp Mol Med.
- 2003 Jun;35(3):203-210.
Cyclooxygenase (COX) is a key enzyme in the conversion of arachidonic acid into prostanoids which participate in various cellular functions including apoptosis, mitogenesis, inflammation, immune modulation and differentiation. Moreover, the... -
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- 5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion
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Choi JH, Park JG, Jeon HJ, Kim MS, Lee MR, Lee MN, Sonn S, Kim JH, Lee MH, Choi MS, Park YB, Kwon OS, Jeong TS, Lee WS, Shim HB, Shin DH, Oh GT
- KMID: 1022122
- Exp Mol Med.
- 2011 Aug;43(8):471-478.
- doi: 10.3858/emm.2011.43.8.053
A variety of benzylidenethiazole analogs have been demonstrated to inhibit 5-lipoxygenase (5-LOX). Here we report the anti-atherogenic potential of 5-(4-hydroxy-2,3,5-trimethylbenzylidene) thiazolidin-2,4-dione (HMB-TZD), a benzylidenethiazole analog, and its potential mechanism of... -
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