- Changes of Blood Testosterone and Dihydrotestosterone Levels in Pediatric Age
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Choi SK, Lee JM
- KMID: 1912289
- Korean J Urol.
- 1988 Oct;29(5):720-724.
A study of changes in testosterone(T) and dihydrotestosterone(DHT) serum concentration was undertaken in children from 6 months to 15 year old age to elucidate the differences in concentration of T... -
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- The Diagnostic Value of the HCG Stimulation Test for 5 alpha-reductase Deficiency in Children
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Choi SK, Kim JW
- KMID: 2289456
- Korean J Urol.
- 1989 Dec;30(6):856-859.
We evaluated 15 children with hypospadias or micropenis for the presence of 5 a-reductase deficiency. Serum testosterone and dihydrotestosterone(DHT) concentrations were measured before and 3 days after HCG stimulation. Also,... -
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- Androgen Hormone Inhibits Expression of iNOS and COX-2 Protein in Rat Vascular Smooth Muscle Cell
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Bae HY, Park JE, Jeon EM, Kang YJ, Lee KY, Choi HC
- KMID: 1600075
- Korean J Physiol Pharmacol.
- 2005 Aug;9(4):215-221.
We investigated the effects of testosterone and dihydrotestosterone on inflammatory response of iNOS and COX-2 expression in rat vascular smooth muscle cells. Rat vascular smooth muscle cells (VSMC) stimulated with... -
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- A Case of Pseudovaginal Perineoscrotal Hypospadias with 5alpha-reductase Deficiency
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Park HS, Yoon HC, Jeong YH, Rho J, Kim CS, Jang DS
- KMID: 2289977
- Korean J Urol.
- 1999 Mar;40(3):398-401.
Male pseudohermaphroditism can be caused by absent m llerian regression, inadequate synthesis of testosterone, inadequate synthesis of dihydrotestosterone, or androgen receptor deficiency. Defects in either the production or the action... -
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- Sustainable Rates of Sebum Excretion in Relation to Menstrual Cycle
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Ryu KO, Lee SH
- KMID: 1891647
- Korean J Dermatol.
- 1988 Dec;26(6):791-796.
Sustainable rates of sebum excretion(SRSE) was measured in seven women who had normal regular periods, none were taking oral contraceptives with no significant signs of acne or hirsutism, with assays... -
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- Effect of Chlormadinone acetate(Prostal
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Lee SE, Chung JY, Kim YK
- KMID: 2114796
- Korean J Urol.
- 1985 Jun;26(3):243-247.
Based on the theory that benign prostatic hypertrophy may be induced by androgenic effect of testosterone derivatives, especially 5-alpha - dihydrotestosterone, on prostatic tissue, Chlormadinone acetate(CMA), potent oral synthetic antiandrogen... -
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- Finasteride Treatment of Female Patterned Hair Loss in Postmenopausal Women
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Ahn JY, Cho SH, Kim MN, Ro BI
- KMID: 1640005
- Korean J Dermatol.
- 2006 Sep;44(9):1094-1097.
Finasteride, an inhibitor of type II 5alpha-reductase, inhibits conversion of testosterone to dihydrotestosterone (DHT), resulting in a decrease in serum and scalp DHT levels which are believed to be pathogenic... -
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- Effect of Dihydrotestosterone Enanthate on Serum Concentrations of Testosterone and Dihydrotestosterone and Testis Weight and Volume in Mice
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Yang HW, Yoon YD
- KMID: 1851748
- J Korean Androl Soc.
- 1994 Dec;12(2):83-91.
The present study was designed to investigate the effects of dihydrotestosterone enanthate(DHTE) on the testis and the serum concentrations of testosterone(T) and dihydrotestosterone(DHT) and to compare these with those... -
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- Pituitary-gonadal Function in Hypospadias
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Kim JW, Choi SK
- KMID: 1912693
- Korean J Urol.
- 1989 Oct;30(5):688-693.
The mechanism by which hypospadias is induced has not yet been clearly clarified. However insufficiency of the hypothalamo-pituitary-gonadal function has been suggested in the hypospadias while conflicting results have been... -
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- Positive Role of Dutasteride in the Treatment of Localized Prostate Cancer
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Kim JH
- KMID: 2307830
- Korean J Urol Oncol.
- 2015 Apr;13(1):24-28.
- doi: 10.0000/kjuo.2015.13.1.24
Dual inhibition of both 5AR1 and 5AR2 by dutasteride provides greater and more consistent inhibition of the conversion of testosterone to dihydrotestosterone (DHT) than selective inhibition of 5AR2 alone. Beyond... -
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- Clinical Experience of Male Pseudohermaphroditism
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Park SO, Yoon JB
- KMID: 1911739
- Korean J Urol.
- 1982 Dec;23(8):1183-1187.
Although the definition of male pseudohermaphroditism remains controversial, male pseudohermaphrodites will be defined as chromatin-negative individuals who have testis with the failure of normal development of the normal male. Also... -
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- Trial of Serum 5alpha-androstane-3alpha,17beta-diol glucuronide for Androgen Therapy in Children
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Han SW, Choi SK
- KMID: 2289724
- Korean J Urol.
- 1994 Aug;35(8):852-857.
Androgen treatment in boys with underdeveloped external genitalia requires close attention to avoid the side effects. The dose and duration of androgen have usually been decided according to the validation... -
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- Hair characteristics and androgenetic alopecia in Koreans
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Choi GS
- KMID: 2192900
- J Korean Med Assoc.
- 2013 Jan;56(1):45-54.
- doi: 10.5124/jkma.2013.56.1.45
The scalp hair is composed of one hundred thousand of hairs. Each hair goes through the three phases of the hair cycle, which causes the hair to turn from an... -
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- Complete Testicular Feminization Syndrome: a Case Report
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Cho MH, Nam ES
- KMID: 2427251
- J Korean Assoc Pediatr Surg.
- 2006 Jun;12(1):47-52.
Testicular feminization syndrome (TFS) is a genetic disorder due to androgen insensitivity of the target organs. The most common clinical presentation of complete TFS is inguinal hernia in the infant... -
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- 5alpha-Reductase
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Park JS, Cho MC, Paick JS
- KMID: 2298803
- Korean J Androl.
- 2012 Apr;30(1):1-12.
- doi: 10.5534/kja.2012.30.1.1
Androgen acts via the androgen receptor and can play a critical role in the development and growth of the prostate and the pathophysiology of prostatic diseases. Testosterone is the most... -
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- A Clinical Investigation for Effect of Chlormadinone acetate(Prostal
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Kwon SW
- KMID: 1911944
- Korean J Urol.
- 1985 Dec;26(6):653-658.
The hypertrophied prostate is the most common cause of infravesical obstrcutions, in the male patients with 50 years old or above. Though the cause of benign prostatic. hypertrophy has not... -
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- A case of 5 alpha reductase deficiency
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Jang MJ, Oh SY, Choi SE, Oh HK, Kim DY, Choi YS
- KMID: 1870367
- Korean J Obstet Gynecol.
- 2007 Mar;50(3):550-554.
5 alpha-reductase deficiency is a rare autosomal recessive disorder caused by mutations in the SRD5A2-gene, resulting in absent or diminished dihydrotestosterone (DHT) formation and, hence, in an underdevelopment of the... -
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- A Study on Plasma Levels of Testosterone, Dihydrotestosterone, Estradiol and Dehydroepiandrosterone-sulfate in Patients with Acne Vulgaris
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Kim JW, Cho MK, Kim KJ, Lee CJ
- KMID: 2086016
- Korean J Dermatol.
- 1998 Feb;36(1):37-46.
BACKGROUND: Although it is evident that androgens have an important role in pathogenesis of acne, the results of current studies on the relationship between serum androgens and acne are inconsistent.... -
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- Disorder of Sex Development with 5alpha-reductase Deficiency in Identical Twins
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Lee ST, Sung K, Byun JL, Yun YM, Chung SC
- KMID: 1482020
- J Korean Soc Pediatr Endocrinol.
- 2008 Dec;13(2):184-187.
Children with abnormal sex development may present with ambiguous genitalia in the newborn period or lacking of secondary sexual characteristics in puberty. Clinicians should make a prompt and accurate diagnosis... -
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- Effect of Neonatal Androgens on Genitofemoral Spinal Motonucleus
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Han SW, Choi SK
- KMID: 2139361
- Korean J Urol.
- 1995 May;36(5):471-482.
The gubernaculum testis, which has an important role to play in transinguinal testicular descent is richly supplied by the genitofemoral nerve through its scrotal attachment. The treatment of pregnant rats... -
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