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Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes

Choi K, Kim YB

Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of...
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Increased glycosylation of human lens epithelial basement membrane in diabetes mellitus

Shin DH, Mandel SS, Lee JH, Ernst B, Newman BL, Juzych M

We studied the nonenzymatic glycosylation of lens epithelial basement membranes (LEBM) of senile cataractous lenses of both diabetic and nondiabetic patients. The human LEBMs were isolated from surgically removed senile...
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Insulin and Glucagon Secretions, and Morphological Change of Pancreatic Islets in OLETF Rats, a Model of Type 2 Diabetes Mellitus

Hong EG, Noh HL, Lee SK, Chung YS, Lee KW, Kim HM

This study was performed to observe the changes of glucose-related hormones and the morphological change including ultrastructure of the pancreatic islets in the male Otsuka Long-Evans Tokushima Fatty rat. Area...
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A Meta-Analysis of the Effects of Exercise Programs on Glucose and Lipid Metabolism and Cardiac Function in Patients with TypeII Diabetes Mellitus

Yoo JS, Lee SJ

  • KMID: 1405800
  • J Korean Acad Nurs.
  • 2005 Jun;35(3):546-554.
PURPOSE: This study was a systematic review and meta-analysis of the effects of exercise programs in patients with type II diabetes mellitus. METHOD: Two investigators systematically searched and...
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The Role of Insulin Resistance in Diabetic Neuropathy in Koreans with Type 2 Diabetes Mellitus: A 6-Year Follow-Up Study

Cho YN, Lee KO, Jeong J, Park HJ, Kim SM, Shin HY, Hong JM, Ahn CW, Choi YC

PURPOSE: We previously reported that insulin resistance, low high-density lipoprotein (HDL) cholesterol, and glycaemic exposure Index are independently associated with peripheral neuropathy in Korean patients with type 2 diabetes mellitus....
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The Effect of Smoking Status upon Occurrence of Impaired Fasting Glucose or Type 2 Diabetes in Korean Men

Park CH, Ga H, Leem JH, Kwak SM, Kim HC, Choi JH

OBJECTIVES: To investigate whether smoking and the smoking status are predictors of the incident impaired fasting glucose (IFG) or type 2 diabetes in Korean men. METHODS: A cohort of...
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Relationship between Milk and Calcium Intake and Lipid Metabolism in Female Patients with Type 2 Diabetes

Kim J, Hwang JY, Kim KN, Choi YJ, Chang N, Huh KB

PURPOSE: This study was conducted to determine the association between intake of milk and dairy products as well as calcium and biomarkers related to lipid metabolism in Korean female patients...
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Impaired homeostatic mechanism of potassium handling after acute oral potassium load in diabetes mellitus

Kim HJ, Ahn YH, Park CH, Kang CM, Park HC

Chronic stable diabetic patients (n = 6) were compared with healthy control subjects (n = 5) after acute oral intake of 50 mEq of potassium chloride (KCl) to investigate for...
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Protective Effects of Curcumin on Renal Oxidative Stress and Lipid Metabolism in a Rat Model of Type 2 Diabetic Nephropathy

Kim BH, Lee ES, Choi R, Nawaboot J, Lee MY, Lee EY, Kim HS, Chung CH

PURPOSE: Diabetic nephropathy is a serious complication of type 2 diabetes mellitus, and delaying the development of diabetic nephropathy in patients with diabetes mellitus is very important. In this study,...
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Altered Renal Sodium Transporter Expression in an Animal Model of Type 2 Diabetes Mellitus

Oh YK, Joo KW, Lee JW, Jeon US, Lim CS, Han JS, Knepper MA, Na KY

Hemodynamic factors play an important role in the development and/or progression of diabetic nephropathy. We hypothesized that renal sodium transporter dysregulation might contribute to the hemodynamic alterations in diabetic nephropathy....
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Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea

Park JS, Kim CS, Nam JY, Kim DM, Jo MH, Park J, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC, Huh KB

The aim of this study was to assess the implications of insulin resistance on the clinical and biochemical profiles of Korean type 2 diabetic patients. 122 patients with type 2...
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