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Treatment-Resistant Depression Entering Remission Following a Seizure during the Course of Repetitive Transcranial Magnetic Stimulation

Kim JW, Bae KY, Kim SW, Kang HJ, Shin IS, Yoon JS, Kim JM

Major depressive disorder is often resistant to antidepressant treatment. Repetitive transcranial magnetic stimulation (rTMS) has been used in treatment-resistant depression (TRD). Known adverse events of rTMS include transient headache, local...
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Left Vagus Nerve Stimulation (VNS) for the Treatment of Depression

Kim HS

  • KMID: 1996817
  • Korean J Psychopharmacol.
  • 2003 Jun;14(2):84-89.
Depressive disorder is one of the very serious mental diseases in terms of personal, social, economical losses. It is not clear for the pathogenesis of the depression, however, even though...
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Baclofen Abuse due to Its Hypomanic Effect in Patients with Alcohol Dependence and Comorbid Major Depressive Disorder

Ghosh S, Bhuyan D

Baclofen is a gamma-aminobutyric acid type B receptor agonist used as an anti-craving agent for treatment of alcohol dependence. It has gained popularity in the recent times because it is...
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Second Generation Antipsychotics in the Treatment of Major Depressive Disorder: An Update

Wang SM, Han C, Lee SJ, Jun TY, Patkar AA, Masand PS, Pae CU

Less than one third of patients who suffer from major depressive disorder (MDD) report remission following antidepressant treatments requiring more diverse treatment approaches. Augmentation of second generation antipsychotics (SGAs) has...
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Paradigm Shift in the Study of Treatment Resistant Depression

Kim YK

Treatment-resistant depression (TRD) is a major public health problem. It is estimated that about 30% of patients with major depressive disorder do not show substantial clinical improvement to somatic or...
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Early Augmentation Response with Low-frequency Repetitive Transcranial Magnetic Stimulation in Treatment Resistant Depression

Singh J, Singh A, Kar SK, Pahuja E

No abstract available.
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The Bipolar Diathesis in Patients with Treatment Resistant Depression

Woo YS, Chae JH, Seo HJ, Song HR, Jun TY, Kim KS, Bahk WM

  • KMID: 2287141
  • Korean J Psychopharmacol.
  • 2006 Sep;17(5):456-460.
OBJECTIVE: In this study, we determined the prevalence of bipolarity in patients with treatment resistant depression (TRD) by investigating demographic and clinical characteristics, diagnostic subtypes, and illness outcome. METHOD: A medical...
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The Epidemiology of Antidepressant Prescriptions in South Korea from the Viewpoint of Medical Providers: A Nationwide Register-Based Study

Kim MJ, Kim N, Shin D, Rhee SJ, Park CH, Kim H, Yang B, Ahn YM

Antidepressants are widely used to treat depression in Korea, however, only a few studies have focused on the provider of the treatment. The aim of the study is to compare...
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Follow-up Study on Electroconvulsive Therapy in Treatment-resistant Depressed Patients after Remission: A Chart Review

Tokutsu Y, Umene-Nakano W, Shinkai T, Yoshimura , Okamoto T, Katsuki A, Hori H, Ikenouchi-Sugita A, Hayashi K, Atake K, Nakamura J

  • KMID: 2171195
  • Clin Psychopharmacol Neurosci.
  • 2013 Apr;11(1):34-38.
OBJECTIVE: Electroconvulsive therapy (ECT) has proven to be effective in treatment-resistant depression (TRD). In recent reports, 70% to 90% of patients with TRD responded to ECT. However, post-ECT relapse is...
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Difficult Clinical Problems of Treatment in Depression

Min KJ

  • KMID: 2142157
  • J Korean Soc Biol Psychiatry.
  • 2001 Jun;8(1):37-46.
Whenever a clinician manages the patients with depression, he may meet various prolems that make it difficult to treat them. Even though he has good skills and knowledge abut depression,...
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Circadian Rhythm Hypotheses of Mixed Features, Antidepressant Treatment Resistance, and Manic Switching in Bipolar Disorder

Lee HJ, Son GH, Geum D

  • KMID: 2316293
  • Psychiatry Investig.
  • 2013 Sep;10(3):225-232.
Numerous hypotheses have been put forth over the years to explain the development of bipolar disorder. Of these, circadian rhythm hypotheses have gained much importance of late. While the hypothalamus-pituitary-adrenal...
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No Association between the Response to the Addition of an Atypical Antipsychotic Drug to an SSRI or SNRI and the BDNF (Val66Met) Polymorphism in Refractory Major Depressive Disorder in Japanese Patients

Yoshimura , Kishi T, Hori H, Ikenouchi-Sugita A, Umene-Nakano W, Katsuki A, Hayashi K, Iwata N, Nakamura J

  • KMID: 2134674
  • Clin Psychopharmacol Neurosci.
  • 2012 Apr;10(1):49-53.
OBJECTIVE: This study examined the association between the brain-derived neurotrophic factor (BDNF) (Val66Met) polymorphism and the response to the addition of an atypical antipsychotic drug to a selective serotonin reuptake...
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Changes in Pre- and Post-Electroconvulsive Therapy Serum Myostatin Levels in Patients with Treatment Resistant Depression

Çelik C, Bolu A, Öznur T, Aydın MS, Tokgöz Y, Uzun O

OBJECTIVE: Myostatin is a growth factor which is investigated regarding musculoskeletal system. Albeit its effect on muscle mass is known, it is considered likely having other unknown effects as well,...
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Comparison of the Bupropion versus Aripiprazole Adjunctive Therapy for the Treatment of Female Depression : Post-Hoc Analyses from a Randomized Prospective Open-Label Multi-Center Study

Keum MS, Cheon EJ, Lee KH, Koo BH, Lee YJ, Park YW, Lee JH, Lee SJ, Sung HM

OBJECTIVES: The purpose of this study was to examine effects of adjunctive aripiprazole versus bupropion, on depressive symptoms of female depression. METHODS: Sixty six female patients with major depressive disorders were...
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Therapeutic Modalities for Treatment Resistant Depression: Focus on Vagal Nerve Stimulation and Ketamine

Shah A, Carreno FR, Frazer A

  • KMID: 2279940
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):83-93.
Treatment resistant depression (TRD) is a global health concern affecting a large proportion of depressed patients who then require novel therapeutic options. One such treatment option that has received some...
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Risperidone as a Janus in Mood Disorder

Yoon DJ

  • KMID: 2202980
  • J Korean Soc Biol Psychiatry.
  • 1997 Nov;4(2):194-197.
To examine the double-faced thymoleptic(antidepressant and antimanic) effects of risperidone in mood disorders, this article reviews the psychotropic-induced mania, thymoleptic effects of antipsychotics, therapeutic effects of risperidone(RIS)-induced mania(RIM) in mood...
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A View of Korean Psychiatrists about Electroconvulsive Therapy

Kim KT, Yoon DJ, Shin YH, Bahn GH, Yum TH

  • KMID: 2340615
  • J Korean Neuropsychiatr Assoc.
  • 2001 Nov;40(6):1072-1089.
OBJECTIVES: Electroconvulsive therapy (ECT) is the important treatment method which has a good effect on refractory depression, schizophrenia at acute stage, patients with suicidal ideation. Although ECT results in better...
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