- Terminal Deoxynucleotidyl Transferase-Mediated Deoxyuridine Triphosphate Nick End Labeling (TUNEL) Assay to Characterize Histopathologic Changes Following Thermal Injury
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Lee JM, Park JH, Kim BY, Kim IH
- KMID: 2399753
- Ann Dermatol.
- 2018 Feb;30(1):41-46.
- doi: 10.5021/ad.2018.30.1.41
BACKGROUND: Despite the wide application of lasers and radiofrequency (RF) surgery in dermatology, it is difficult to find studies showing the extent of damage dependent on cell death. OBJECTIVE: We evaluated... -
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- What should be done for men with sperm DNA fragmentation?
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Kim GY
- KMID: 2419525
- Clin Exp Reprod Med.
- 2018 Sep;45(3):101-109.
- doi: 10.5653/cerm.2018.45.3.101
In an age when a small quantity of sperm can lead to pregnancy through in vitro fertilization or intracytoplasmic sperm injection, selecting healthy sperm is important. Sperm DNA fragmentation (SDF)... -
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- Placental Apoptosis in Preeclampsia
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Choi WJ, Shin JG, Choi WS, Lee JH, Paik WY
- KMID: 1613421
- Korean J Perinatol.
- 2002 Sep;13(3):267-273.
OBJECTIVE: To investigate the change of placental apoptosis and the expression of their mediator in preeclampsia women. METHODS: Placental tissues from 10 cases of preeclampsia and 15 cases of normal pregnancy... -
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- Altered Trophoblastic Apoptosis in Early Pregnancy Losses
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Lee PY, Kim BH, Yoo HK, Won HS, Park EJ, Lee JH, Lee IS, Huh JR, Kim A, Nam CH
- KMID: 2261395
- Korean J Obstet Gynecol.
- 1999 Jun;42(6):1201-1206.
OBJECTIVE:Our purpose was to investigate whether trophoblastic apoptosis is related with early pregnancy losses. METHODS: Placentas were collected from 22 uncomplicated first-trimester pregnancies undergoing elective surgical abortion for social reason... -
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- Placental apoptosis in preeclampsia
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Kim HJ, Kim YH, Ahn KY, Nam KI, Kim SM, Song TB, Byun JS
- KMID: 2076237
- Korean J Obstet Gynecol.
- 2001 Apr;44(4):787-792.
OBJECTIVE: Our purpose was to investigate the incidence of placental apoptosis in pregnancies complicated by preeclampsia. METHODS: Placental samples were obtained from 15 uncomplicated third-trimester pregnancies and from 17 pregnancies... -
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- Expression of Survivin in Gastric Carcinoma and its Relation to Tumor Cell Proliferation and Apoptosis
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Lee WS, Cho SB, Rew JS, Lee JH, Park CS, Joo YE
- KMID: 2459592
- Korean J Pathol.
- 2009 Aug;43(4):329-334.
BACKGROUND: Survivin, a novel antiapoptotic gene has been linked with tumor development and progression in various human carcinomas including gastric carcinomas. The aim of this study was to evaluate the... -
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- The Time Evolution of Cerebral Apoptosis in the Permanent Middle Cerebral Artery Occlusion Model in Rats
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Shin CS, Choi BY, Jung ES, Kim SW, Chang CH, Cho SH
- KMID: 1817829
- J Korean Neurosurg Soc.
- 2005 Jan;37(1):54-58.
OBJECTIVE: The purpose of this study is to determine the time evolution and distribution of cerebral apoptosis using the middle cerebral artery occlusion model in rats. METHODS: A total of... -
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- Relationship Between Apoptotic Index and Prognostic Factors in Epithelial Ovarian Cancer
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Choi HW, Lee SK, Lee JH, Kim SB
- KMID: 2075814
- Korean J Obstet Gynecol.
- 1999 Jul;42(7):1428-1435.
OBJECTIVE: To determine the relationship between apoptotic index[apoptotic cells/1000 tumor cells, AI], bcl-2, and p53 protein expression and clinicopathologic factors and prognosis in epithelial ovarian cancer. METHODS: We obtained 36... -
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- Placental Apoptosis from Pregnancies Complicated by Fetal Growth Restriction or Preeclampsia: Expression of Bcl-2, Bax and p53
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Park JH, Kim SR, Song ES, Im MW, Lee BI, Lee WY
- KMID: 2272567
- Korean J Obstet Gynecol.
- 2005 Apr;48(4):891-900.
OBJECTIVE: The purpose of this study was to investigate the degree of apoptosis in placentas with pregnancy complicated by fetal growth restriction or preeclampsia as compared with normal term pregnancy... -
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- The Expression of Thymidylate Synthase in Breast Cancer
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Park JK, Kim JS, Kim KH, Jeon HM, Suh YJ, Park WC, Oh SC, Jung SS, Kim JS, Im SA
- KMID: 2173618
- J Korean Breast Cancer Soc.
- 1999 Dec;2(2):227-239.
- doi: 10.4048/jkbcs.1999.2.2.227
Fluorouracil is well known as a standard chemotherapeutic drug in breast cancer and other cancers that is converted to flurodeoxyuridine monophosphate (FdUMP) and leads to the inhibition of thymidylate synthase... -
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- Disparity between MR Imaging and Histochemical Grading in Human Intervertebral Disc Degeneration
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Lee JH, Chung CK, Kim HJ
- KMID: 2018759
- J Korean Neurosurg Soc.
- 2006 Jun;39(6):432-437.
OBJECTIVE: In order to establish the index of degeneration, the authors performed a histochemical study with Safranin-O staining and investigated the occurrence of apoptosis in the human intervertebral disc. METHODS:... -
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- Study on the Apoptosis and its Mediators in the Placentas of Preclampsia using cDNA Expression Array
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Choi WJ, Choi WS, Lee JH, Paik WY
- KMID: 2271954
- Korean J Obstet Gynecol.
- 2003 Feb;46(2):259-267.
OBJECTIVE: The present study was designed to examine whether preeclampsia is associated with an increase in placental apoptosis and to detect differential expression of mediators involved in apoptosis. METHODS: Placental tissues... -
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- Association Between Apoptosis and Development of the Cervical Neoplasia
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Kim TJ, Kim JW, Kim HS, Chun YK, Paik DJ, Lim KT, Jung HW, Lee KH, Park IS, Park CT, Shim JU
- KMID: 2083734
- Korean J Gynecol Oncol Colposc.
- 1999 Jun;10(2):138-147.
Apoptosis, including the programmed cell death, is important event in normal cell turnover and maintenance of adult tissues. Apoptosis exerts a homeostatic function in relation to tissues dynamics, as the... -
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- Intratumoral Injection of Holmium-Chitosan Complex in Prostate Cancer
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Hong SH, Lee SJ, Kim SW, Lee CB, Kang SH, Cho YH, Yoon MS
- KMID: 1764819
- Korean J Urol.
- 2004 Mar;45(3):229-235.
PURPOSE: The aim of this study was to pathologically evaluate the therapeutic and toxic effects of the 166Ho-chitosan complex(166HC) on prostatic cancer. MATERIALS AND METHODS: The DU-145 cell line was subcutaneously... -
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- Clinicopathologic Significance of Survivin Expression in Relation to CD133 Expression in Surgically Resected Stage II or III Colorectal Cancer
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Li W, Lee MR, Choi E, Cho MY
- KMID: 2367676
- J Pathol Transl Med.
- 2017 Jan;51(1):17-23.
- doi: 10.4132/jptm.2016.09.23
BACKGROUND: Cancer stem cells have been investigated as new targets for colorectal cancer (CRC) treatment. We recently reported that CD133+ colon cancer cells showed chemoresistance to 5-fluorouracil through increased survivin... -
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- Trophoblast Apoptosis and BRCA1 Expression in Fetal Growth Restriction Pregnancy
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Moon CS, Chung JY
- KMID: 2013146
- Korean J Obstet Gynecol.
- 2006 Mar;49(3):527-535.
OBJECTIVE: To know the role of trophoblast apoptosis and BRCA1 on pregnancy of intra-uterine fetal growth restriction (FGR). BRCA1 is regarded as not only a tumor suppressor gene but regulator... -
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- Comparison of Apoptosis and Bcl-2 Expression in Normal Pregnancy, Pregnancy Induced Hypertension and Intrauterine Growth Restriction
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Kim HS, Noh HT, Rhee YE, Song KS
- KMID: 2272270
- Korean J Obstet Gynecol.
- 2004 Feb;47(2):278-286.
OBJECTIVE: The purpose of this study was to investigate the incidence of apoptosis and expression of bcl-2 in the placenta of normal pregnancy, Pregnancy Induced Hypertension, and Intrauterine Growth Restriction. METHODS:... -
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- The Different Effects of Testicular Torsion on the Contralateral Testis between Pubertal and Adult Rats
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Jeong SJ, Choi WS, Ha SB, Jeong MS, Chung JS, Baek M, Hong SK, Choi H
- KMID: 2314782
- Korean J Urol.
- 2009 Jul;50(7):704-710.
PURPOSE: Our study aimed to determine whether the severity of damage to the contralateral testis by ipsilateral testicular torsion/detorsion in pubertal rats, which have an incomplete blood-testis barrier, is different... -
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- Expression of Thymidylate Synthase in Non-Small Cell Lung Cancer
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Yoo J, Kim S, Shim BY, Kim SH, Song SH, Cho DG, Ahn MI, Kim CH, Cho KD, Kang SJ, Kim HK
- KMID: 2073756
- Korean J Pathol.
- 2005 Dec;39(6):412-417.
BACKGROUND: Thymidylate synthase (TS) catalyzes the methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), and this is an essential step in DNA biosynthesis. The present investigation was designed... -
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- Effects of supplementation with antifreeze proteins on the follicular integrity of vitrified-warmed mouse ovaries: Comparison of two types of antifreeze proteins alone and in combination
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Kim MK, Kong HS, Youm HW, Jee BC
- KMID: 2408581
- Clin Exp Reprod Med.
- 2017 Mar;44(1):8-14.
- doi: 10.5653/cerm.2017.44.1.8
OBJECTIVE: The aim of this study was to analyze the effect of supplementing vitrification and warming solutions with two types of antifreeze proteins (AFPs) and the combination thereof on the... -
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