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Effect of metabolic shock induced by 2-deoxy-D-glucose on the murine immune response

Kim YS, Jang SI, Lee SE, Lee BS, Chung HT

  • KMID: 1690585
  • Korean J Immunol.
  • 1993 May;15(1):37-43.
No abstract available.
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Effects of Insulin, 2-Deoxyglucose and Dichloroacetate on Acute Focal Cerebral Ischemia in Rats

Chung HS, Park YK, Lee HG, Lee KC, Chu JW

  • KMID: 1688190
  • J Korean Neurosurg Soc.
  • 1991 May;20(5):336-344.
Hyperglycemia has been reported to worsen the tolerance of the brain to ischemia, and it has therefore been recommended that patient undergoing neurosurgical procedures not receive glucose-containing solutions. Since ischemic...
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The Effect of Angiotensin II on Hypoxic Pulmonary Vasoconstriction in Isolated Rabbit Lung

Park KS, Ahn WS, Ham BM

BACKGROUND: The isolated lung model is a very useful model in investigation of hypoxic pulmonary vasoconstriction (HPV), and angiotensin II is extensively used in this model. But the exact role...
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Effects of Metabolism Inhibited by Deoxyglucose on Hypoxic Pulmonary Vasoconstriction in the Isolated Rabbit Lung

Ahn WS, Kim SD, Huh J

BACKGROUND: Hypoxic pulmonary vasoconstriction (HPV) is a defense mechanism to maintain adequate oxygenation. It has been reported that metabolism inhibition augments HPV. The purpose of the present study...
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Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Findings of Post Traumatic Lymphangioma in a Young Adult Male

Kwon SD, Chun KA, Kong EJ, Cho IH

The authors report the case of a 34-year-old male, who underwent a fluorine-18 fluoro deoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) scan 7 years after trauma for the evaluation of...
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A Pictorial Review on Extraosseous Manifestations of Multiple Myelomas

Seo JM, Lee KS, Yi CA, Kim SH, Park BK, Han BK, Kim HJ

Extraosseous involvement of multiple myelomas can be seen clinically or radiologically in approximately 10-20% of patients at the time of initial diagnosis and may develop in an additional 15% of...
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Random Synchronous Malignancy in Male Breast: A Case Report

Sarma M, Borde C, Subramanyam P, Shanmuga Sundaram P

We report here a case of a random synchronous male breast malignancy in a patient with a known base of tongue malignancy that was incidentally detected on a whole body...
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The Effects of D-Chiro-Inositol on Glucose Metabolism in 3T3-L1 Cells

Park KS, Lee JM, Ku BJ, Jo YS, Lee SK, Min KW, Han KA, Kim HJ, Kim HJ

BACKGROUND: The target of the treatment of metabolic syndrome and diabetes is an improvement of insulin resistance. D-chiro-inositol (DCI) plays a role in a phospholipid mediating intracellular insulin action. In...
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The Effect of Hypoxia on the Release of Endothelium-derived Relaxing Factor in Rabbit Thoracic Aorta

Choi SS

  • KMID: 2062943
  • Korean J Thorac Cardiovasc Surg.
  • 2009 Oct;42(5):588-596.
BACKGROUND: To clarify the effect of hypoxia on vascular contractility, we tried to show whether hypoxia induced the release of endothelium-derived relaxing factor (EDRF) and the nature of the underlying...
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Role of 18F 2-fluoro-2-deoxyglucose Positron Emission Tomography in Upper Gastrointestinal Malignancies

Yun HW, Shim KN

The 18F 2-fluoro-2-deoxyglucose (FDG) PET/CT scan is an imaging modality used in the management of patients with various types of malignancies. 18F-FDG PET/CT has demonstrated significant efficacy in the staging...
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The Roles of Glycated Albumin as Intermediate Glycation Index and Pathogenic Protein

Kim KJ, Lee BW

The conventional glycemic indices used in management of diabetic patients includes A1c, fructosamine, 1,5-anhydroglucitol, and glycated albumin (GA). Among these indices, A1c is currently used as the gold standard. However,...
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Serial Positron Emission Tomography Findings and Neuropsychological Assessments in Limbic Encephalitis

Kim TE, Park JH, Lee TK, Sung KB, Park SA

  • KMID: 1910327
  • Soonchunhyang Med Sci.
  • 2014 Jun;20(1):7-13.
OBJECTIVE: Limbic encephalitis (LE) is characterized by rapid development of impaired cognitive function, seizure and psychiatric symptoms. Brain 18fluoro labelled deoxyglucose (18FDG)-positron emission tomography (PET) typically showed glucose hypermetabolism in...
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Enhanced Radiosensitivity and Chemosensitivity of Breast Cancer Cells by 2-Deoxy-D-Glucose in Combination Therapy

Aghaee F, Pirayesh Islamian J, Baradaran

Breast cancer is the most common malignancy, and it is also the major cause of cancer-related deaths of women worldwide. Breast cancer treatment involves surgery, chemotherapy, radiation therapy, or combination...
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Oxidative Stress Causes Vascular Insulin Resistance in OLETF Rat Through Increased IRS-1 Degradation

Park JL, Lee YS, Kim BH, Kang YH, Kim IJ, Kim YK, Son SM

BACKGROUND: Insulin resistance and oxidative stress have been reported to play essential pathophysiological roles in diabetic cardiovascular complication. The relationship between insulin resistance and oxidative stress in vasculature remains unclear....
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Review of the Potential Glycemic Markers Glycated Albumin and 1,5-anhydroglucitol

Kim WJ, Park CY

The measure of HbA1c is the gold standard index of glycemic control in clinical practice for diabetes treatment and is well known as a risk marker for diabetes complications. However,...
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Effects of 2-deoxy-D-glucose and quercetin on the expression of osteonectin and osteopontin during the differentiation of irradiated MC3T3-E1 osteoblastic cells

Yu SK, Koh KJ, Kim KA

  • KMID: 1483924
  • Korean J Oral Maxillofac Radiol.
  • 2008 Dec;38(4):195-202.
PURPOSE: To characterize the effects of 2-deoxy-D-glucose (2-DG) and quercetin (QCT) on gene expression of osteonectin (ON) and osteopontin (OP) in irradiated MC3T3-E1 cells. MATERIALS AND METHODS: When MC3T3-E1 osteoblastic cells...
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Nitric Oxide Increases Insulin Sensitivity in Skeletal Muscle by Improving Mitochondrial Function and Insulin Signaling

Lee WJ, Kim HS, Park HS, Kim MO, Kim M, Yun JY, Kim EH, Lee SA, Lee SH, Koh EH, Park JY, Lee KU

BACKGROUND: Accumulating evidence has suggested that nitric oxide (NO) is involved in the regulation of insulin sensitivity in skeletal muscle. Recent studies also suggested NO as an important molecule regulating...
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Early Metabolic Flare in Squamous Cell Carcinoma after Chemotherapy is a Marker of Treatment Sensitivity In Vitro

Bjurberg M, Abedinpour P, Brun E, Baldetorp , Borgstrom , Wennerberg J, Kjellen E

  • KMID: 1455391
  • Nucl Med Mol Imaging.
  • 2010 Sep;44(3):165-169.
PURPOSE: Early metabolic response with a decrease in glucose demand after cytotoxic treatment has been reported to precede tumor volume shrinkage. However, preclinical studies report of a very early rise...
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O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes

Park SY, Ryu J, Lee W

  • KMID: 1056235
  • Exp Mol Med.
  • 2005 Jun;37(3):220-229.
It has been known that O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of proteins plays an important role in transcription, translation, nuclear transport and signal transduction. The increased flux of glucose through the...
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Effects of 2-deoxy-D-glucose and quercetin on osteoblastic differentiation and mineralization in irradiated MC3T3-E1 cells

Ahn HS, Kim KA, Koh KJ

  • KMID: 2034134
  • Korean J Oral Maxillofac Radiol.
  • 2006 Dec;36(4):189-198.
PURPOSE: To investigate the in vitro response of MC3T3-E1 osteoblastic cells to X-ray in the presence and absence of 2 deoxy-D-glucose (2-DG) and quercetin (QCT). MATERIALS AND METHODS: The MC3T3-E1...
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