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Aberrant Promoter Methylation of Death-Associated Protein Kinase in Serum DNA from Lung Cancer Patients

Lee JH, Lee JW, Jung KS, Kim KU, Lee TK, Lee KW, Na MA, Jeon DS, Choi YM, Kim YS, Lee MK, Park SK

  • KMID: 2318433
  • Tuberc Respir Dis.
  • 2003 Oct;55(4):378-387.
BACKGROUND: Promoter methylation of tumor suppressor genes is one of the key epigenetic changes in many human cancers. The aim of this study was to evaluate the promoter methylation status...
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Aberrant Methylation of p16 Tumor Suppressor Gene and Death-Associated Protein Kinase in Non-Small Cell Lung Carcinoma

Kim YS, Lee MK, Jung KS, Kim KU, Kim YD, Lee HR, Lee CH, Seok JW, Kim YK, Jun ES, Choi YM, Rha SH, Park SK

BACKGROUND: The p16INK4a (p16) tumor suppressor gene is frequently inactivated in human non-small cell lung cancers (NSCLCs), predominantly through homozygous deletion or in association with aberrant promotor hypermethylation. Death-associated protein...
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Transcriptome Analysis Identifies an Attenuated Local Immune Response in Invasive Nonfunctioning Pituitary Adenomas

Kim YH, Kim JH

BACKGROUND: Invasive nonfunctioning pituitary adenomas (NFPAs) remain challenging due to their high complication rate and poor prognosis. We aimed to identify the distinctive molecular signatures of invasive NFPAs, compared with...
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