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Tracing the Variation in Physiological Response to Rifampicin Across the Microbial Spectrum

Dey A, Chatterji

Rifampicin is an acknowledged inhibitor of bacterial RNA polymerase. We observed that there exists a substantial variation in the basal-level tolerance to rifampicin across microbial species. A number of mechanisms...
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A New Record of Penicillium antarcticum from Marine Environments in Korea

Park MS, Lee EJ, Fong JJ, Sohn JH, Lim YW

  • KMID: 2312732
  • Mycobiology.
  • 2014 Jun;42(2):109-113.
During a survey of marine fungi from the waters surrounding Jeju Island, Korea, several Penicillium strains were isolated from seawater and marine sponges. Based on morphological characteristics and phylogenetic analyses...
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rpoB Gene Analysis of helicobacter pylori

Rhee KH, Kook YH, Cho MJ, Lee SH, Kim BJ, Kim SJ, Lim CY, Lee KH, Yeo SJ

  • KMID: 2146901
  • J Korean Soc Microbiol.
  • 1999 Aug;34(4):401-408.
rpoB, which encodes the B subunit of RNA polymerase, is related to rifampin resistance of Mycobacterium tuberculosis and Escherichia coli. We determined the nucleotide sequences (346 bp) of rpoB gene...
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Identification of Mycobacteria by Comparative Sequence Analysis and PCR - Restriction Fragment Length Polymorphism Analysis

Kook YH

  • KMID: 2099316
  • J Korean Soc Microbiol.
  • 1999 Dec;34(6):561-571.
Diagnosis of mycobacterial infection is dependent upon the isolation and identification of causative agents. The procedures involved are time consuming and technically demanding. To improve the laborious identification process mycobacterial...
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Molecular Discrimination of Mitis Group Streptococci Isolated from Koreans using RpoB Nucleotide Sequences

Park SN, Kook JK

  • KMID: 1431126
  • Int J Oral Biol.
  • 2013 Mar;38(1):29-36.
Mitis group streptococci (MGS) were classified based on the nucleotide sequences 16S rRNA gene (16S rDNA) and comprised 13 Streptococcus species. However, 16S rDNA homogeneity among MGS was too high...
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Rescue of Synthetic Hantavirus-Like Foreign RNA by Hantavirus as a Helper Virus

Park MS, Jeong DH, Lee PW

  • KMID: 1573311
  • J Bacteriol Virol.
  • 2002 Sep;32(3):269-277.
A system for the expression of synthetic hantavirus-like luciferase RNA was developed using Hantaan (HTN) virus as a helper virus. The hantavirus-like luciferase RNA was constructed by the deletion of...
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Establishment of androgen-dependent cells from Shionogi carcinoma 115(SC115)

Kim BW, Kwon TG, Kim CH, Park YB

  • KMID: 2036822
  • Korean J Urol.
  • 1992 Apr;33(2):193-199.
Hormone-dependent cancers including prostatic cancer respond to endocrine therapy in initial phase, but gradually loss responsiveness and eventually show autonomous growth despite of continuation or the treatment At present it...
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Understanding Rifampicin Resistance in Tuberculosis through a Computational Approach

Kumar S, Jena L

The disease tuberculosis, caused by Mycobacterium tuberculosis (MTB), remains a major cause of morbidity and mortality in developing countries. The evolution of drug-resistant tuberculosis causes a foremost threat to global...
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Development of Quantitative Real-Time PCR Primers for the Detection of Aggregatibacter actinomycetemcomitans

Park SN, Park JY, Kook JK

  • KMID: 2135277
  • Int J Oral Biol.
  • 2011 Mar;36(1):1-6.
The purpose of this study was to develop species-specific real-time quantitative PCR (RT-qPCR) primers for use in the detection of Aggregatibacter actinomycetemcomitans. These primers were designed based on the nucleotide...
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Norwalk-Like Viruses, A Common Cause of Sporadic Acute Gastroenteritis in korean Children

Kim KH, Xiang X

  • KMID: 1943466
  • J Korean Soc Microbiol.
  • 1997 Apr;32(2):227-236.
Norwalk-like virus (NLV), one of the emerging enteric pathogens in sporadic cases and outbreaks of acute gastroenteritis (AG) worldwide, are 30-35 nm in diameter and have a single stranded RNA...
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Effect of CRP (cAMP Receptor Protein) of Escherichia coli on Transcription Initiation at lacUV5 Promoter

Kim SY, Kwon H, Ryu S, Park C, Lee K

  • KMID: 2146929
  • J Korean Soc Microbiol.
  • 1998 Aug;33(4):391-398.
The cyclic AMP receptor protein (CRP) complexed with cyclic AMP (CRP.cAMP) regulates expression of many genes by binding to sites at or near many promoters of Escherichia coli. The regulatory...
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Mutation of rpoB gene in M leprae isolates from Korea

Kim JP, Kim YS

  • KMID: 1512578
  • Korean Lepr Bull.
  • 2007 Dec;40(2):3-14.
Global efforts to control leprosy by intensive chemotherapy, including rifampin, have led to a significant decrease in the number of registered patients. But emergence of rifampin-resistant strains of pathogenic mycobacteria...
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Isolation and Complete Nucleotide Analysis of a Noncytopathic BVDV Variant using a Dominant Selective Marker

Lee YM

  • KMID: 1572914
  • J Bacteriol Virol.
  • 2002 Mar;32(1):63-72.
Upon infection, bovine viral diarrhea virus (BVDV), one of the pestiviruses in the Flaviviridae family, is divided into two biotypes, cytopathic (cp) and noncytopathic (ncp). The mechanism of cytopathogenicity, however,...
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Identification of Fastidious Mycobacteria other than M. tuberculosis ( MOTT ) by Comparative Sequence Analysis of rpoB and 16S rDNA

Kim BJ, Im SI, Kim YW, Bai GH, Kim SJ, Lee KH, Cha CY, Kook YH

  • KMID: 1572904
  • J Bacteriol Virol.
  • 2002 Mar;32(1):39-45.
Conventional tests for the identification of mycobacteria may frequently result in erroneous identification and underestimate the diversity within the genus Mycobacterium. However, this problem can be overcome by molecular approach...
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CD5 mRNA Overexpression in Lymphocytes of Allergic Patients

Noh GW, Kang YS, Moon IG, Lee WG

  • KMID: 2083000
  • Korean J Immunol.
  • 1997 Sep;19(3):347-354.
PURPOSE: The CD5 molecules are pan-T cell antigens and are found on a minor subpopulation of B cells. CD5 antigens are involed in an intracellular signal transduction as well as...
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Detection of Major bcr/abl mRNA from Stored Bone Marrow Aspirate Smears Using the Reverse Transcriptase Polymerase Chain Reaction

Lee EY, Shin JH, Jun ES

  • KMID: 2089457
  • Korean J Clin Pathol.
  • 1997 Aug;17(4):668-675.
BACKGROUND: The verse transcriptase polymerase chain reaction (RT-PCR) has been widely used to analyze the bcr/abl fusion mRNA in chronic myelogenous leukemia (CML). Fresh or cryopreserved cells may not always...
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Development of Quantitative Real-Time PCR Primers for Detection of Prevotella intermedia

Park SN, Kook JK

Prevotella intermedia-specific quantitative real-time PCR (qPCR) primers were previously designed based on the nucleotide sequences of RNA polymerase beta-subunit gene (rpoB). However, the several clinical strains isolated from Korean populations...
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Development of Quantitative Real-Time PCR Primers for Detection of Streptococcus sobrinus

Park SN, Kook JK

The purpose of this study was to develop Streptococcus sobrinus-specific qPCR primers based on the nucleotide sequence of the RNA polymerase β-subunit gene (rpoB). The specificity of the primers was...
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Detection of rpoB Gene Mutation in Rifampin-Resistant M. Tuberculosis by Oligonucleotide Chip

Park S, Lee M, Chung B, Kim C, Chang C, Park H, Jang H, Park S, Song S

BACKGROUND: Oligonucleotide chip technology has proven to be a very useful tool in the rapid diagnosis of infectious disease. Rifampin resistance is considered as a useful marker of multidrug-resistance in...
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Detection of Prevotella intermedia and Prevotella nigrescens using Pn17 and Pn34 DNA Probes

Park CH, Kim PS, Kim HS, Min JB, Hwang HK, Jang HS, Cho KW, Baek DH, Kook JK

  • KMID: 1719928
  • Int J Oral Biol.
  • 2010 Mar;35(1):13-19.
The DNA probes Pn17 and Pn34 were evaluated for their ability to specifically detect clinical strains of P. intermedia and P. nigrescens from a Korean population by dot blot hybridization....
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