- Multiple Roles of BRIT1/MCPH1 in DNA Damage Response, DNA Repair, and Cancer Suppression
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Lin SY, Liang Y, Li K
- KMID: 1074978
- Yonsei Med J.
- 2010 May;51(3):295-301.
- doi: 10.3349/ymj.2010.51.3.295
Mammalian cells are frequently at risk of DNA damage from both endogenous and exogenous sources. Accordingly, cells have evolved the DNA damage response (DDR) pathways to monitor and assure the... -
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- Characterization of Mutator Pathway in Younger-age-onset Colorectal Adenocarcinomas
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Roh SA, Kim HC, Kim JS, Kim JC
- KMID: 2157655
- J Korean Med Sci.
- 2003 Jun;18(3):387-391.
- doi: 10.3346/jkms.2003.18.3.387
The high-frequency microsatellite instability (MSI-H) phenotype, frequently identified in hereditary nonpolyposis colorectal cancer (HNPCC), also accounts for approximately 15% of sporadic colorectal cancers. Microsatellite instability (MSI) occurs from the mutational... -
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