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The effect of growth factor on antigen and viability of corneal endothelial cells

Tchah H

The effect of epidermal growth factor (EGF) on corneal endothelial cell of rabbit, was evaluated. DNA synthesis of cultured corneal endothelial cells after adding EGF to culture medium and major...
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Role of Hepatic Stellate Cells in the Angiogenesis of Hepatoma

Jung JO, Gwak GY, Lim YS, Kim CY, Lee HS

  • KMID: 772536
  • Korean J Gastroenterol.
  • 2003 Aug;42(2):142-148.
BACKGROUND/AIMS: Hepatic stellate cells (HSCs) in the hepatocellular carcinoma are responsible for tumor encapsulation as a host defense mechanism. Recently, it was suggested that HSCs might play an important...
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The effect of anti-hypertensive drugs on DNA synthesis and proliferation of ultured rat aortic smooth muscle cells

Kang SW, Lee IH, Choi KH, Lee HY, Han DS

The aim of this study was to elucidate the effects of anti-hypertensive drugs, nifedipine, furosemide, hydrochlorothiazide, captopril, and atenolol on DNA synthesis and proliferation of cultured rat aortic...
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Hyperoxia influences mRNA expression of cytokines in cultured human umbilical vein endothelial cells

Park MS, Wallace HM

High concentrations of oxygen, indispensable for the treatment of severe hypoxemia from neonatal as well as adult respiratory distress syndrome, increase the risk of oxygen toxicity. Biochemical mechanisms are lipid...
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Effect of Centrifugal Force on Cellular Activity of Osteoblastic MC3T3-E1 Cells in vitro

Lee DH, Park JC, Suh H

The effects of centrifugal force on growth and differentiation of osteoblastic cells cultured in alpha-MEM containing 1% Fetal bovine serum were investigated by assays of DNA synthesis, alkaline phosphatase activity...
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Effects of prostaglandins on ethanol damage in primary cultured rat hepatocytes

Yang JM, Choi SW, Kim SS, Sun HS, Park DH, Han SB, Oh GT, Kim WM

  • KMID: 759062
  • Korean J Intern Med.
  • 1998 Feb;13(1):1-9.
OBJECTIVES: Several reports demonstrated that ethanol administration impairs the DNA synthesis in rat hepatocytes. Also, it has been demonstrated that prostaglandin (PG) helps prevent membrane damage by hepatotoxic chemicals. In ...
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Angiotensin II stimulates proliferation of adventitial fibroblasts cultured from rat aortic explants

Kim DK, Huh JE, Lee SH, Hong KP, Park JE, Seo JD, Lee WR

It has been proposed that the local renin-angiotensin system is activated in the adventitia after vascular injury. However, the physiological role of Angiotensin II (Ang II) in the adventitia has...
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Expressions of c-fos and c-myc genes during 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB)-induced rat hepatocarcinoma

Chai KJ, Kim JS, Lee HK

We investigated the expression of the growth-related nuclear proto-oncogenes, c-fos and c-myc, in early preneoplastic regions and tumor nodules of 3'-MeDAB induced rat hepatocarcinoma. To amplify the levels of these...
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TGF-betas Synthesized by RPE Cells Have Autocrine Activity on Mesenchymal Transformation and Cell Proliferation

Lee SC, Kim SH, Koh HJ, Kwon OW

The present study investigated the effects of transforming growth factor (TGF)-beta on retinal pigment epithelial (RPE) transformation in a simplified model and also whether or not TGF-beta exhibits similar proliferation...
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The effective concentration and exposure time of mitomycin-C for the inhibition of lens epithelial cell proliferation in rabbit eyes

You YS, Lim SJ, Chung HS, Lee YG, Kim CY, Hong YJ

The proliferation of residual lens epithelial cells following cataract surgery is assumed to be a major cause of posterior capsular opacification. To assess the efficacy of mitomycin-C in preventing posterior...
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Catechins inhibit angiotensin II-induced vascular smooth muscle cell proliferation via mitogen-activated protein kinase pathway

Won SM, Park YH, Kim HJ, Park KM, Lee WJ

  • KMID: 1098087
  • Exp Mol Med.
  • 2006 Oct;38(5):525-534.
Catechins, components of green tea, reduce the incidence of cardiovascular diseases such as atherosclerosis. Angiotensin II (Ang II) is highly implicated in the proliferation of vascular smooth muscle cells (VSMC),...
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