- Immunogenicity and reactogenicity of a yeast recombinant DNA hepatitis B vaccine in healthy subjects
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Kim KM, Chu SE, Lee HR, Yoon HS, Lee KM, Min CH
- KMID: 1687926
- J Korean Soc Microbiol.
- 1991 Dec;26(6):493-498.
No abstract available. -
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- Construction of Recombinant DNA with F and HN Genes of Newcastle Disease Virus and Its Immunogenicity
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Kim JY, Chu J, Park JH, Seo SH, Park CS, Kim MC, Jun MH
- KMID: 2055016
- J Bacteriol Virol.
- 2006 Jun;36(2):99-107.
- doi: 10.4167/jbv.2006.36.2.99
Recombinant DNA vaccines, based on plasmid vectors expressing an antigen under the control of a strong promotor, have several advantages over traditional vaccines. They have been shown to induce a... -
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- Construction of a Mycobacterium - Escherichia coli Shuttle Vector and Use in the Expression of Foreign Genes in Mycobacteria
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Cho SN, Kim JD, Lee HY, Kim HJ
- KMID: 1540524
- J Korean Soc Microbiol.
- 1997 Jun;32(3):293-300.
The ability to introduce recombinant DNA molecules back into mycobacteria would greatly increase the potential of molecular genetic approaches for the study of mycobacteria as well as for the use... -
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- Production of CD44v6 Antibody Fragments and Comparision of Their Speciticities
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Han I, Zeon SK, Park KK
- KMID: 1550740
- Korean J Immunol.
- 1999 Dec;21(4):303-309.
CD44v6 was known as tumor marker for tumor progression and metastasis in various kinds of carcinomas. The CD44v6 monoclonal antibody was produced by cell cultures or mouse ascite fluids using... -
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- Strategy for Novel Vaccine and Antivirals Against Foot-and-Mouth Disease
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Park JH, Kim SM, Lee KN, Ko YJ, Lee HS, Cho IS
- KMID: 1456248
- J Bacteriol Virol.
- 2010 Mar;40(1):1-10.
- doi: 10.4167/jbv.2010.40.1.1
Foot-and-mouth disease (FMD) is a highly contagious, virally induced disease of cloven-hoofed animals. FMD-affected countries have suffered from a serious economic impact due to their decreased participation in the international... -
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- Two Cases of Psoriasis Following Growth Hormone Therapy
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Heo YS, Jeong SY, Choi JE, Seo SH, Ahn HH, Kye YC
- KMID: 2247822
- Korean J Dermatol.
- 2009 Jun;47(6):714-717.
Growth hormone (GH) has been available for more than 4 decades for the treatment of GH deficiency. But mass production of recombinant DNA growth hormone has made GH therapy widely... -
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- Development of epidemiological method for the Helicobacter pylori by polymerase chain reaction
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Lee WK, Cho MJ, Choi HJ, Rhee KH
- KMID: 1421876
- J Korean Med Sci.
- 1991 Dec;6(4):338-347.
- doi: 10.3346/jkms.1991.6.4.338
The polymerase chain reaction was used to develop a method for the detection of Helicobacter pylori, a causative agent of gastritis, as well as for the elucidation of its mode... -
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- New Vaccine Technology for Control of Emerging and Reemerging Infectious Diseases
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Kang JH
- KMID: 2303880
- Korean J Epidemiol.
- 2006 Jun;28(1):41-46.
Although the development of vaccines has been one of the most important contributions of immunology to medicine and public health, and despite vaccination having been proven as the most effective... -
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- Molecular cloning and expression of 3beta-hydroxy steroid dehydrogenase in E-Coli
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Oh JM
- KMID: 1937887
- Korean J Anat.
- 1998 Oct;31(5):771-778.
This study was carried out to obtain the 3beta-hydroxy-5-ene steroid dehydrogenase (3beta-HSD) which is contained in human trophoblasts. To produce 3beta-HSD cDNA, reverse transcription-polymerase chain reaction (RT-PCR) with the total... -
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- A Case of Severe Hypertension associated with Growth Hormone Therapy
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Heo N, Oh CH, Huh J, Oh PS, Lee HJ, Yoon HS
- KMID: 2193672
- J Korean Soc Pediatr Endocrinol.
- 2001 Jun;6(1):77-84.
The use of recombinant DNA technology to produce human growth hormone has resulted in a marked increase in availability of Growth Hormone(GH) to treat short stature due to GH deficiency... -
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- Effects of Addition of Sugars on the Stability of Hepatitis B Virus Vaccine
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Seong I
- KMID: 1541341
- J Korean Soc Virol.
- 1997 Dec;27(2):143-149.
Most of the current licenced hepatitis B vaccines are being produced by recombinant DNA technology in large fermentation cultures of Saccharomyces cerevisiae of yeast cells which carry the gene coded... -
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- Brain Tumor Immunology: Part II : Immunotherapy of Malignant Brain Tumors
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Hong YK, Rha HK, Jung CK, Lee SW, Jo TH, Baik MW, Yoon SH, Kang JK, Song JU, Choi CR
- KMID: 2067857
- J Korean Neurosurg Soc.
- 1990 Dec;19(10-12):1389-1396.
The prognosis of patients with malignant brain tumors has improved only slightly despite the combined use of surgery, radiation therapy, and chemotherapy. Immunotherapy offers some possibilities and hopes as a... -
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- Synergistic Effect of Trabectedin and Olaparib Combination Regimen in Breast Cancer Cell Lines
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Avila-Arroyo S, Nunez GS, Garcia-Fernandez LF, Galmarini
- KMID: 2176281
- J Breast Cancer.
- 2015 Dec;18(4):329-338.
- doi: 10.4048/jbc.2015.18.4.329
PURPOSE: Trabectedin induces synthetic lethality in tumor cells carrying defects in homologous recombinant DNA repair. We evaluated the effect of concomitant inhibition of nucleotide-excision repair and poly (ADP-ribose) polymerase (PARP)... -
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- Recombinant DNA and Protein Vaccines for Foot-and-mouth Disease Induce Humoral and Cellular Immune Responses in Mice
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Bae JY, Moon SH, Choi JA, Park JS, Hahn BS, Kim KY, Kim B, Song JY, Kwon DH, Lee SC, Kim JB, Yang JS
- KMID: 2150655
- Immune Netw.
- 2009 Dec;9(6):265-273.
- doi: 10.4110/in.2009.9.6.265
BACKGROUND: Foot-and-mouth disease virus (FMDV) is a small single-stranded RNA virus which belongs to the family Picornaviridae, genus Apthovirus. It is a principal cause of FMD which is highly contagious... -
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- Clinical Effects of E. coli Derived Recombinant Human Growth Hormone (DA - 3001) in Patients with Growth Hormone Deficiency
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Yang SW, Shin JH, Kim DH, Lee BC, Moon HR
- KMID: 2462172
- J Korean Soc Endocrinol.
- 1995 Dec;10(4):377-385.
Recently, methionyl-hGH was produced in the E. coil K-12, W3110 by recombinant DNA technology in Korea. In this paper, the clinical efficacy and immunogenicity of this GH were studied in... -
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- Structural Analysis of Recombinant Human Preproinsulins by Structure Prediction, Molecular Dynamics, and Protein-Protein Docking
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Jung SH, Kim CK, Lee G, Yoon J, Lee M
- KMID: 2404051
- Genomics Inform.
- 2017 Dec;15(4):142-146.
- doi: 10.5808/GI.2017.15.4.142
More effective production of human insulin is important, because insulin is the main medication that is used to treat multiple types of diabetes and because many people are suffering from... -
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- Growth hormone treatment in non-growth hormone-deficient children
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Loche S, Carta L, Ibba A, Guzzetti C
- KMID: 1702656
- Ann Pediatr Endocrinol Metab.
- 2014 Mar;19(1):1-7.
- doi: 10.6065/apem.2014.19.1.1
Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities... -
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- Clinical Effects of E. cole Derived Authentic REcombinant Human Growth Hormone(DA-3002) in Children with Growth Hormone Deficiency
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Yang SW, Lee BC, Ko CW, Kim DH, Yoo HW, Chung WY
- KMID: 1944211
- J Korean Soc Endocrinol.
- 1998 Dec;13(4):526-535.
BACKGROUND: Recently authentic human growth hormone(hGH) has produced in the E coli K-12, W3110 by recombinant DNA tecbnology in Korea In this paper, the clinical efficacy and immunogenicity of this... -
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- Purification of treponema pallidum from rabbit testicular tissue
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Lee MG, Cho SW, Lee KH, Lee JB
- KMID: 2231234
- Korean J Dermatol.
- 1991 Feb;29(1):56-64.
There are several different methods of purifying Treponema pallidum(TP) from rabbit testicular tissue. Among them, we compared the use of differential centrifugation, which has been most widely used, to Percoll... -
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- The present and future of craniofacial surgery in Korea
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Kim S
- KMID: 2190732
- J Korean Med Assoc.
- 2011 Jun;54(6):576-580.
- doi: 10.5124/jkma.2011.54.6.576
The five major areas of concern in craniofacial surgery are the cleft lip and palate, hemifacial microsomia, craniosynostosis and its accompanying craniofacial syndromes, maxillofacial surgery, and breakthrough research on the... -
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