- Natural Killer Cell Activity in Rheumatoid Arthritis Measured by a Single Cell Cytotoxicity Assay
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Kim GS, Youn JK, Kim JD, Kim NH
- KMID: 1119203
- Yonsei Med J.
- 1988 Jun;29(2):160-165.
- doi: 10.3349/ymj.1988.29.2.160
The natural killer(NK) cell activity of mononuclear cells (MNC) from peripheral blood (PB) and synovial fluid (SF) of 40 rheumatoid arthritis(RA) patients was investigated by employing 51-chromium-(51Cr) release microcytotoxicity and... -
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- The role of nitric oxide as an effector of macrophage-mediated cytotoxicity against Trichomonas vaginalis
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Park GC, Ryu JS, Min DY
- KMID: 658271
- Korean J Parasitol.
- 1997 Sep;35(3):189-195.
- doi: 10.3347/kjp.1997.35.3.189
The purpose of this study is to determine whether nitric oxide is involved in the extracellular killing of Trichomonas vaginalis by mouse (BALB/c) peritoneal macrophages and RAW264.7 cells... -
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- Comparison of hemostatic efficacy and cytotoxicity of three ferric subsulfate- and chitosan-based styptics in different formulations using a rat tail bleeding model
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Byun JY, Lee S, Lee JI, Yoon HY
- KMID: 2437681
- Korean J Vet Res.
- 2018 Sep;58(3):119-124.
- doi: 10.14405/kjvr.2018.58.3.119
This study was conducted to compare the hemostatic efficacy of three ferric subsulfate- and chitosan-based styptics as a powder and a gel containing ferric subsulfate and chitosan (FSC-PO and FSC-G,... -
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- Tumor-Specific Immunity Induced by Cryoablation in a Murine Renal Cell Carcinoma Model
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Kim HK, Pyun JH, Cho S, Kang SG, Lee JG, Kim JJ, Cheon J, Park HS, Kang SH
- KMID: 2070099
- Korean J Urol.
- 2014 Dec;55(12):834-840.
- doi: 10.4111/kju.2014.55.12.834
PURPOSE: To evaluate tumor-specific immunity and define the mechanisms involved in the cryoimmunologic response, we compared the tumor control efficacy and immunologic responses of cryoablation with those of surgical excision... -
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- Degradation of human immunoglobulins and cytotoxicity on HeLa cells by live Trichomonas vaginalis
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Min DY, Ryu JS, Park SY, Shin MH, Cho WY
- KMID: 1715335
- Korean J Parasitol.
- 1997 Mar;35(1):39-46.
- doi: 10.3347/kjp.1997.35.1.39
The present study was undertaken to determine whether live T. vaginalis degrades human secretory IgA, serum IgA and IgG molecules. Human immunoglobulins were exposed to live trophozoites, parasite lysate, and... -
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- Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation
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Kim JY, Son YO, Park SW, Bae JH, Chung JS, Kim HH, Chung BS, Kim SH, Kang CD
- KMID: 1098081
- Exp Mol Med.
- 2006 Oct;38(5):474-484.
In this study, we have investigated if current cancer therapeutic modalities including hyperthermia and ionizing radiation can increase the expression of NKG2D ligands in human cancer cell lines. The expressions... -
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- Evaluation of cytolytic activity and phenotypic changes of circulating blood immune cells in patients with colorectal cancer by a simple preparation of peripheral blood mononuclear cells
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Kim JC, Choi J, Lee SJ, Lee YA, Jeon YM, Kang YW, Lee JK
- KMID: 2324877
- J Korean Surg Soc.
- 2013 Nov;85(5):230-235.
PURPOSE: This study aimed to assess the cytolytic activity and the phenotype of circulating blood immune cells in cancer patients by using a simple preparation of peripheral blood mononuclear cells... -
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- Anti-tumor immunostimulatory effect of heat-killed tumor cells
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Yoon TJ, Kim JY, Kim H, Hong C, Lee H, Lee CK, Lee KH, Hong S, Park SH
- KMID: 1103596
- Exp Mol Med.
- 2008 Feb;40(1):130-144.
- doi: 10.3858/emm.2008.40.1.130
As a part of our ongoing search for a safe and efficient anti-tumor vaccine, we attempted to determine whether the molecular nature of certain tumor antigens would influence immune responses... -
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- Detection of Cancer by Culturing Cancerous Tissue In Plastico
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Lee WY, Kim JD, Kim BS
- KMID: 1758482
- Yonsei Med J.
- 1983 Jun;24(1):1-5.
- doi: 10.3349/ymj.1983.24.1.1
In a previous report, it was felt that the rat tumor cell line, T-333, was a mixture of heterogeneous cells with different characteristics with respect to karyotype, tumorigenicity, and response... -
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- Characterization of a novel anti-human TNF-alpha murine monoclonal antibody with high binding affinity and neutralizing activity
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Song MY, Park SK, Kim CS, Yoo TH, Kim B, Kim MS, Kim YS, Kwag WJ, Lee BK, Baek K
- KMID: 1103586
- Exp Mol Med.
- 2008 Feb;40(1):35-42.
- doi: 10.3858/emm.2008.40.1.35
In order to develop an anti-human TNF-alpha mAb, mice were immunized with recombinant human TNF-alpha. A murine mAb, TSK114, which showed the highest binding activity for human TNF-alpha was selected... -
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- Influence of primary tumor site on host anti-tumor immunity
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Choi SH, Lim TS, Hwang EH
- KMID: 1120237
- Yonsei Med J.
- 1992 Sep;33(3):258-264.
- doi: 10.3349/ymj.1992.33.3.258
Stage IV-S neuroblastoma, characterized by a primary tumor plus disseminated tumors in liver, skin and bone marrow, has a favorable clinical prognosis when compared to metastatic Stage IV neuroblastoma. This... -
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- Suppression of Tumor Formation and Induction of Natural Killer Cell Activity in BALB/c Nude Mice by Human B7-1 (CD80) Gene Transfer Subcutaneously Injected with Human Hepatocellular Carcinoma Cells (Huh-7)
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Yoon SK, Kim TG, Cho HI, Lee BS, Cho SH, Han NI, Lee YS, Jang JW, Chung KW, Sun HS, Kim BS
- KMID: 863146
- Korean J Hepatol.
- 2003 Jun;9(2):124-134.
BACKGROUND/AIMS: Immunogene therapy is extensively studied for a therapeutic modality of various cancers. This study was conducted to investigate the efficacy of immunogene therapy using the T-cell costimulatory molecule... -
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- Inhibition of Lewis Lung Carcinoma Growth by Toxoplasma gondii through Induction of Th1 Immune Responses and Inhibition of Angiogenesis
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Kim JO, Jung SS, Kim SY, Kim TY, Shin DW, Lee JH, Lee YH
- KMID: 1785787
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S38-S46.
- doi: 10.3346/jkms.2007.22.S.S38
Toxoplasma gondii is an obligate intracellular protozoan parasite that induces antitumor activity against certain types of cancers. However, little information is available regarding the immunologic mechanisms that regulate these effects.... -
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- Body Fat Percentage and Natural Killer Cell Activity of Breast and Rectal Cancer Patients after Diagnosis but before Treatment
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Kim DS, Jun MH
- KMID: 820085
- J Korean Acad Nurs.
- 2008 Apr;38(2):321-331.
- doi: 10.4040/jkan.2008.38.2.321
PURPOSE: To examine the relationship between body fat percentage (BFP) and N-K cell activity (NKCA) in Korean breast and rectal cancer patients just after diagnosis. METHODS: With 35 subjects... -
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- Selective addition of CXCR3+CCR4-CD4+ Th1 cells enhances generation of cytotoxic T cells by dendritic cells in vitro
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Yoon SH, Yun SO, Park JY, Won HY, Kim EK, Sohn HJ, Cho HI, Kim TG
- KMID: 1123463
- Exp Mol Med.
- 2009 Mar;41(3):161-170.
- doi: 10.3858/emm.2009.41.3.019
Increasing importance is being given to the stimulation of Th1 response in cancer immunotherapy because its presence can shift the direction of adaptive immune responses toward protective immunity. Based on... -
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- Immunomodulatory and antitumor effects in vivo by the cytoplasmic fraction of Lactobacillus casei and Bifidobacterium longum
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Lee JW, Shin JG, Kim EH, Kang HE, Yim IB, Kim JY, Joo HG, Woo HJ
- KMID: 1094686
- J Vet Sci.
- 2004 Mar;5(1):41-48.
The immunomodulatory and antitumor effects of lactic acid bacteria (LABs) were investigated. Cytoplasmic fraction of Lactobacillus acidophilus, Lactobacillus casei and Bifidobacterium longum were tested for the antiproliferative activity in vitro... -
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- In vitro induction of anterior gradient-2-specific cytotoxic T lymphocytes by dendritic cells transduced with recombinant adenoviruses as a potential therapy for colorectal cancer
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Lee HJ, Hong CY, Kim MH, Lee YK, Nguyen-Pham TN, Park BC, Yang DH, Chung IJ, Kim HJ, Lee JJ
- KMID: 1120143
- Exp Mol Med.
- 2012 Jan;44(1):60-67.
- doi: 10.3858/emm.2012.44.1.006
Anterior gradient-2 (AGR2) promotes tumor growth, cell migration, and cellular transformation, and is one of the specific mRNA markers for circulating tumor cells in patients with gastrointestinal cancer. We investigated... -
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- Two-signal blockade with anti-CD45RB and anti-CD154 monoclonal antibodies inhibits graft rejection via CD4-dependent mechanisms in allogeneic skin transplantation
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Kim EY, Lee EN, Lee J, Park HJ, Chang CY, Jung DY, Choi SY, Lee SK, Joh JW, Kim SJ
- KMID: 1094154
- Exp Mol Med.
- 2006 Jun;38(3):284-294.
Blockade of signal 1 or 2 for T-cell activation by the use of anti-CD45RB and anti-CD154 monoclonal antibodies (mAb) (two-signal blockade) has been proven effective in preventing or delaying graft... -
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