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Mutational Analysis of KRAS, BRAF, and TP53 Genes of Ovarian Serous Carcinomas in Korean Women

Cho YH, Kim DY, Kim JH, Kim YM, Kim KR, Nam JH, Kim YT

  • KMID: 2396071
  • Yonsei Med J.
  • 2009 Apr;50(2):266-272.
PURPOSE: To assess the prevalence of KRAS, BRAF, and TP53 mutations in cases of low-grade and high-grade serous carcinomas and to evaluate the clinical outcomes of these morphologically distinct carcinomas....
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Estimation of Prognostic Marker Genes by Public Microarray Data in Patients with Ovarian Serous Cystadenocarcinoma

Yang SD, Jang SS, Han JA, Park HS, Kim JI

PURPOSE: Lymphatic invasion (LI) is regarded as a predictor of the aggressiveness of ovarian cancer (OC). However, LI is not always the major determinant of long-term patient survival. To establish...
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The NER-related gene GTF2H5 predicts survival in high-grade serous ovarian cancer patients

Gayarre J, Kamieniak , Cazorla-Jimenez A, Munoz-Repeto I, Borrego S, Garcia-Donas J, Hernando S, Robles-Diaz L, Garcia-Bueno JM, Ramon y Cajal T, Hernandez-Agudo E, Heredia Soto V, Marquez-Rodas I, Echarri MJ, Lacambra-Calvet C, Saez R, Cusido M, Redondo A, Paz-Ares L, Hardisson , Mendiola M, Palacios J, Benitez J, Garcia MJ

OBJECTIVE: We aimed to evaluate the prognostic and predictive value of the nucleotide excision repair-related gene GTF2H5, which is localized at the 6q24.2-26 deletion previously reported by our group to...
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