- Cloning and characterization of Giardia intestinalis cyclophilin
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Yu HS, Kong HH, Chung DI
- KMID: 1720456
- Korean J Parasitol.
- 2002 Sep;40(3):131-138.
- doi: 10.3347/kjp.2002.40.3.131
The cyclophilins (Cyps) are family members of proteins that exhibit peptidylprolyl cis-trans isomerase (PPIase, EC 5.2.1.8) activity and bind the immunosuppressive agent cyclosprin A (CsA) in varying degrees. During the... -
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- Cyclophilin A: A Mediator of Cardiovascular Pathology
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Soe NN, Berk BC
- KMID: 1492131
- J Korean Soc Hypertens.
- 2011 Dec;17(4):133-147.
- doi: 10.5646/jksh.2011.17.4.133
Cyclophilin A (CyPA) is a 17 kDa, ubiquitously expressed multifunctional protein that possesses peptidylprolyl cis-trans isomerase activity and scaffold function. Its expression is increased in inflammatory conditions including rheumatoid arthritis,... -
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- The Future of B-cell Activating Factor Antagonists in the Treatment of Systemic Lupus Erythematosus
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Stohl W
- KMID: 2378084
- J Rheum Dis.
- 2017 Apr;24(2):65-73.
- doi: 10.4078/jrd.2017.24.2.65
To review B-cell activating factor (BAFF)-antagonist therapy in systemic lupus erythematosus (SLE), literature was searched using the search words and phrases, “BAFFâ€, “B lymphocyte stimulator (BLyS)â€, “a proliferation-inducing ligand (APRIL)â€,... -
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- Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus-induced Hepatocellular Carcinoma
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Lee J
- KMID: 1500231
- Korean J Physiol Pharmacol.
- 2013 Oct;17(5):375-383.
- doi: 10.4196/kjpp.2013.17.5.375
Hepatocellular carcinoma (HCC) related to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections is thought to account for more than 80% of primary liver cancers. Both HBV and... -
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- Protective Effect of Right Ventricular Mitochondrial Damage by Cyclosporine A in Monocrotaline-induced Pulmonary Hypertension
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Lee DS, Jung YW
- KMID: 2424563
- Korean Circ J.
- 2018 Dec;48(12):1135-1144.
- doi: 10.4070/kcj.2018.0061
BACKGROUND AND OBJECTIVES: Mitochondria play a key role in the pathophysiology of heart failure and mitochondrial permeability transition pore (MPTP) play a critical role in cell death and a critical... -
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- cDNA Microarray Analysis of Differential Gene Expression in Gastric Cancer Cells Sensitive and Resistant to 5-Fluorouracil and Cisplatin
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Ahn MJ, Yoo YD, Lee KH, Ahn JI, Yu DH, Lee HS, Oh HS, Choi JH, Lee YS
- KMID: 1743356
- Cancer Res Treat.
- 2005 Feb;37(1):54-62.
PURPOSE: Gastric cancer is one of the most prevalent cancers worldwide. 5-fluorouracil (5-FU) and cisplatin are the most commonly used drugs for the treatment of gastric cancer. However, a significant... -
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