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Increased Expression of Cyclooxygenase-2 is Associated with the Progression to Cirrhosis

Jeong SW, Jang JY, Lee SH, Kim SG, Cheon YK, Kim YS, Cho YD, Kim HS, Lee JS, Jin SY, Shim CS, Kim BS

BACKGROUND/AIMS: To investigate the degree of cyclooxygenase-2 (COX-2) protein expression in chronic hepatitis and cirrhosis. METHODS: COX-2 protein expression was evaluated in 43 cases of chronic hepatitis and 24 cases...
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The Expression of Multiple Proteins as Prognostic Factors in Colorectal Cancer: Cathepsin D, p53, COX-2, Epidermal Growth Factor Receptor, C-erbB-2, and Ki-67

Shin IY, Sung NY, Lee YS, Kwon TS, Si Y, Lee YS, Oh ST, Lee IK

  • KMID: 1774523
  • Gut Liver.
  • 2014 Jan;8(1):13-23.
BACKGROUND/AIMS: A single gene mutation alone cannot explain the poor prognosis of colorectal cancer. This study aimed to establish a correlation between the expression of six proteins and the prognosis...
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PMK-S005 Alleviates Age-Related Gastric Acid Secretion, Inflammation, and Oxidative Status in the Rat Stomach

Choi YJ, Kim N, Lee JY, Nam RH, Suh JH, Lee SM, Ham MH, Jo HJ, Shim YK, Park YH, Lee JC, Choi YJ, Lee HS, Lee DH

BACKGROUND/AIMS: The aim of this study was to evaluate the effect of the synthetic S-allyl-l-cysteine (SAC) PMK-S005 on gastric acid secretion, inflammation, and antioxidant enzymes in aging rats. METHODS: The rats...
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