- Expression of Cyclooxygenase-1 and -2 in Synovial Tissues from Patients with Rheumatoid Arthritis
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Lee YH, Choi SJ, Ji JD, Kim A, Kim CH, Song GG
- KMID: 2142255
- J Korean Rheum Assoc.
- 1998 Nov;5(2):159-168.
No abstract available. -
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- Expression of cyclooxygenase-1, -2 in human uterine cervix during gestational period
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Oh JH, Kim HS, Yang JI, Kim MS, Yang SC, Han GS, Keum SS, Oh GS
- KMID: 2262123
- Korean J Obstet Gynecol.
- 2000 Nov;43(11):2014-2019.
OBJECTIVE: To determine whether cyclooxygenase (COX)-1 and COX-2 are expressed differentially during the whole gestational period in the pregnant human uterine cervix and if they are involved in the process... -
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- Analgesic and Anti-inflammatory Effects of Ibuprofen, Indomethacin and NS-398 on an Acute Model of Arthritis in Rats
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Kim NJ, Park JY, Han HC, Chang SH
- KMID: 1936258
- Korean J Anesthesiol.
- 2001 Jun;40(6):802-814.
- doi: 10.4097/kjae.2001.40.6.802
BACKGROUND: All currently available nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit both cyclooxygenase-1 and cyclooxygenase-2 and exhibit many complications. It has been suggested that the anti-inflammatory and also most of... -
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- Peripheral Analgesic and Anti-inflammatory Effects of Diclofenac, SC-560 and NS-398 on Acute Arthritic Model in Rats
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Park HS, Park JY, Han HC, Lim HJ, Chang SH, Yoon SM
- KMID: 2236701
- Korean J Anesthesiol.
- 2004 Mar;46(3):336-341.
- doi: 10.4097/kjae.2004.46.3.336
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) are generally attributed to suppression cyclooxygenase enzymes, leading to decreased products of the arachidonic acid cascade. Since the discovery of two isoenzymes of cyclooxygenase, inhibition... -
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- Expression of Cyclooxygenase-1, -2 in Human Uterine Cervix of Preterm and Term Pregnancies
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Kim HS, Kim MS, Yang HW, Yang JI, Ahn EJ, Oh KS
- KMID: 2075714
- Korean J Obstet Gynecol.
- 1999 Apr;42(4):784-789.
OBJECTIVE: The purpose of this study was to determine whether cyclooxygenase [COX]-1 and COX-2 are expressed in the pregnant human uterine cervix and if they are expressed differentially between preterm... -
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- Nitric Oxide Donor, NOR-3, Increased Expression of Cyclooxygenase-2, but not of Cyclooxygenase-1 in Cultured VSMC
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Lee DH, Park JE, Kang YJ, Lee KY, Choi HC
- KMID: 2285328
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):161-165.
NO and cyclooxygenase-2 (COX-2) are contributes to vascular inflammation induced by various stimulation. The mechanism, which explains a linkage between NO and COX-2, could be of importance in promoting pathophysiological... -
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- Melittin-induced Nociceptive Responses are Alleviated by Cyclooxygenase-1 Inhibitor
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Kim J, Shin HK, Lee KH
- KMID: 1512941
- Korean J Physiol Pharmacol.
- 2006 Feb;10(1):45-50.
Melittin-induced pain model has been known to be very useful for the study of pain mechanism. Melittin-induced nociceptive responses are reported to be modulated by the changes in the activity... -
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- Effects of Armeniacae Semen and Amygdalin on the Lipopolysaccaride-induced Prostaglandin E2 Synthesis and Nitric Oxide Production in Mouse BV2 Microglial Cells
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Jung HJ, Kim YS, Shin MS, Kim CJ, Kim YS
- KMID: 2165285
- Exp Neurobiol.
- 2008 Dec;17(2):71-78.
- doi: 10.5607/en.2008.17.2.71
Armeniacae semen has been used in traditional medicine for the treatment of pain and inflammatory diseases. Amygdalin is the major compound of Armeniacae semen, and it is used for treatment... -
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- Inhibitory Effects of Epigallocatechin-3-Gallate on Microsomal Cyclooxygenase-1 Activity in Platelets
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Lee DH, Kim YJ, Kim HH, Cho HJ, Ryu JH, Rhee MH, Park HJ
- KMID: 2170686
- Biomol Ther.
- 2013 Jan;21(1):54-59.
In this study, we investigated the effect of (-)-epigallocatechin-3-gallate (EGCG), a major component of green tea catechins from green tea leaves, on activities of cyclooxygenase (COX)-1 and thromboxane synthase (TXAS),... -
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- Cyclic Expression of Cyclooxygenase-1 and -2 in Human Endometrium
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Park DW, Yang HW, Kwon HC, Hwang KJ, Yoo JY, Lee CH, Kim SK, Cho DJ, Oh KS
- KMID: 2085101
- Korean J Fertil Steril.
- 1998 Apr;25(1):25-33.
Cyclooxygenase (COX) is an enzyme involved in the conversion of arachidonic acid to prostaglandins(PGs), and exists in two forms, COX-1 and COX-2. COX has been reported to be involved in... -
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- 3-Dimensional Culture System of Endometrial Cells for Studying the Human Implantation Mechanism
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Park DW, Yang HW, Kwon HC, Chang KH, Kim SK, Cho DJ, Oh KS
- KMID: 2085112
- Korean J Fertil Steril.
- 1999 Apr;26(1):1-8.
In order to study the implantation mechanism various methods for culture of endometrial cells in vitro have been attempted. However, a disadvantage is that primary cultures of stromal and epithelial... -
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- Ethanol extract of Angelica gigas inhibits croton oil-induced inflammation by suppressing the cyclooxygenase - prostaglandin pathway
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Shin S, Joo SS, Park D, Jeon JH, Kim TK, Kim JS, Park SK, Hwang BY, Kim YB
- KMID: 1106156
- J Vet Sci.
- 2010 Mar;11(1):43-50.
- doi: 10.4142/jvs.2010.11.1.43
The anti-inflammatory effects of an ethanol extract of Angelica gigas (EAG) were investigated in vitro and in vivo using croton oil-induced inflammation models. Croton oil (20 microgram/mL) up-regulated mRNA expression... -
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- NF-kappaB Binding Activity and Cyclooxygenase-2 Expression in Persistent betaCCI(4)-Treated Rat Liver Injury
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Kim SH, Chu HJ, Kang DH, Song GA, Cho M, Yang US, Kim HJ, Chung HY
- KMID: 648675
- J Korean Med Sci.
- 2002 Apr;17(2):193-200.
- doi: 10.3346/jkms.2002.17.2.193
The involvement of NF-kappaB binding activity is known to be important in the mechanism of acute liver injury and in the induction of cyclooxygenase (COX-2). This study was performed to... -
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- A Case of Diphyllobothrium nihonkaiense Infection as Confirmed by Mitochondrial COX1 Gene Sequence Analysis
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Park SH, Eom KS, Park MS, Kwon OK, Kim HS, Yoon JH
- KMID: 1715695
- Korean J Parasitol.
- 2013 Aug;51(4):471-473.
- doi: 10.3347/kjp.2013.51.4.471
Diphyllobothrium nihonkaiense has been reported in Korea as Diphyllobothrium latum because of their close morphologic resemblance. We have identified a human case of D. nihonkaiense infection using the mitochondrial cytochrome... -
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- Pilot study of the use of Yin Qiao San in children with conventional antipyretic hypersensitivity
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Liew WK, Loh W, Chiang WC, Goh A, Chay OM, Iancovici Kidon M
- KMID: 2397039
- Asia Pac Allergy.
- 2015 Oct;5(4):222-229.
- doi: 10.5415/apallergy.2015.5.4.222
BACKGROUND: Children with a diagnosis of cross-reactive hypersensitivity to both paracetamol and nonsteroidal anti-inflammatory drugs are limited in their choice of antipyretics. OBJECTIVE: The aim of this pilot study is to... -
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- Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats
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Choi YJ, Kim N, Lee JY, Nam RH, Seo JH, Lee S, Kim HJ, Choi YJ, Lee HS, Lee DH
- KMID: 2411960
- Gut Liver.
- 2016 May;10(3):348-355.
- doi: 10.5009/gnl14509
BACKGROUND/AIMS: This study aimed to examine the gastroprotective effects of PMK-S005, which is a synthetic S-allyl-L-cysteine (SAC; a sulfur-containing amino acid), against acute ethanol-induced gastric damage in rats. METHODS: Sprague-Dawley rats... -
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- Cordycepin-Enriched WIB801C from Cordyceps militaris Inhibits Collagen-Induced [Ca2+]i Mobilization via cAMP-Dependent Phosphorylation of Inositol 1, 4, 5-Trisphosphate Receptor in Human Platelets
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Lee DH, Kim HH, Cho HJ, Yu YB, Kang HC, Kim JL, Lee JJ, Park HJ
- KMID: 2170640
- Biomol Ther.
- 2014 May;22(3):223-231.
In this study, we prepared cordycepin-enriched (CE)-WIB801C, a n-butanol extract of Cordyceps militaris-hypha, and investigated the effect of CE-WIB801C on collagen-induced human platelet aggregation. CE-WIB801C dose-dependently inhibited collagen-induced platelet aggregation,... -
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- Extracorporeal Worm Extraction of Diphyllobothrium nihonkaiense with Amidotrizoic Acid in a Child
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Shin HK, Roh JH, Oh JW, Ryu JS, Goo YK, Chung DI, Kim YJ
- KMID: 2069820
- Korean J Parasitol.
- 2014 Dec;52(6):677-680.
- doi: 10.3347/kjp.2014.52.6.677
Infection cases of diphyllobothriid tapeworms are not much in the below teen-age group. We report a case of Diphyllobothrium nihonkaiense infection in a 13-year-old boy. He presented with severe fatigue,... -
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- Human bone marrow-derived mesenchymal stem cell gene expression patterns vary with culture conditions
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Lee MW, Kim DS, Yoo KH, Kim HR, Jang IK, Lee JH, Kim SY, Son MH, Lee SH, Jung HL, Sung KW, Koo HH
- KMID: 2172908
- Blood Res.
- 2013 Jun;48(2):107-114.
- doi: 10.5045/br.2013.48.2.107
BACKGROUND: Because of the heterogeneity of human mesenchymal stem cells (MSCs), methods for cell expansion in culture and the effects on gene expression are critical factors that need to be... -
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- The IL-1B Genetic Polymorphism Is Associated with Aspirin-Induced Peptic Ulcers in a Korean Ethnic Group
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Cho JH, Choi JS, Chun SW, Lee S, Han KJ, Kim HM
- KMID: 2411962
- Gut Liver.
- 2016 May;10(3):362-368.
- doi: 10.5009/gnl15129
BACKGROUND/AIMS: Single nucleotide polymorphisms (SNPs) are associated with aspirin-induced peptic ulcers. However, SNPs of specific genes vary among races, and data regarding SNPs in the Korean population are scarce. In... -
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