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A Case of Dilated Cardiomyopathy with Massive Left Ventricular Thrombus after Use of a Sibutramine-Containing Slimming Product

Heo SH, Kang MH

Sibutramine, which acts as an anti-obesity drug by inhibiting reuptake of serotonin and norepinephrine, has now been banned due to cardiovascular adverse effects. However, despite being banned, it is not...
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Weight Loss Drugs Recently Approved by the FDA

Lee CB

There have been many advances in obesity treatment, including life-style modification and pharmacological and surgical treatments. It seems that the most remarkable advances in obesity treatment are those of pharmacological...
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Phentermine, Sibutramine and Affective Disorders

An H, Sohn H, Chung S

  • KMID: 2171190
  • Clin Psychopharmacol Neurosci.
  • 2013 Apr;11(1):7-12.
A safe and effective way to control weight in patients with affective disorders is needed, and phentermine is a possible candidate. We performed a PubMed search of articles pertaining to...
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Anti-Obesity Drugs: A Review about Their Effects and Safety

Kang JG, Park CY

The current recommendations for the treatment of obese people include increased physical activity and reduced calories intake. When the behavioral approach is not sufficient, a pharmacologic treatment is recommended. In...
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16 Cases of Anti-obesity Drug Intoxication Experienced in 4 Emergency Departments

Han SH, So BH, Jung WJ, Kim HM

  • KMID: 1426779
  • J Korean Soc Clin Toxicol.
  • 2012 Dec;10(2):111-117.
PURPOSE: In Korea, few studies have examined the acute toxicity of anti-obesity drugs. The purpose of this study is to analyze the general characteristics and clinical aspect of acute anti-obesity...
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Changes of Body Weight and Inflammatory Markers after 12-Week Intervention Trial: Results of a Double-Blind, Placebo-Control Pilot Study

Joo NS, Kim SM, Kim KM, Kim CW, Kim BT, Lee DJ

PURPOSE: Low grade inflammation is a well-known characteristic in obese subjects. We investigated body weight changes and inflammatory markers after 12-week intervention trial. MATERIALS AND METHODS: Twenty-six obese subjects were enrolled...
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The Effects of Non-surgical Weight Reduction on Daytime Sleepiness and Fatigue in Patients with Obstructive Sleep Anpea

Kang SG, Kim SH, Park SJ, Kim HN, Park YJ, Song SW

  • KMID: 2270957
  • Korean J Obes.
  • 2011 Dec;20(4):177-184.
BACKGROUND: Among the many complications caused by obesity, the most common respiratory complication is upper respiratory obstruction during sleep caused by snoring. Long term snoring may lead to obstructive sleep...
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Sibutramine (Reductil(R))-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report

Ha YJ, Han YJ, Choi YW, Myung KB, Choi HY

  • KMID: 2383264
  • Ann Dermatol.
  • 2011 Nov;23(4):544-547.
A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil(R), Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week...
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Dangyuja (Citrus grandis Osbeck) Peel Improves Lipid Profiles and Alleviates Hypertension in Rats Fed a High-Fat Diet

Hong HJ, Jin JY, Yang H, Kang WY, Kim DG, Lee S, Choi Y, Kim JH, Han CH, Lee YJ

Obesity is a major public health problem and significant risk factor for many serious diseases including coronary artery disease, cancer, and diabetes. This study was performed to investigate the hypolipidemic...
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A Case of Acute Psychosis after Sibutramine Ingestion

Kim HM, Woo SH, Choi SM, So BH

  • KMID: 1848459
  • J Korean Soc Clin Toxicol.
  • 2009 Dec;7(2):176-179.
A 38-year-old woman was admitted to our hospital due to agitation, nausea, chest discomfort, tachycardia and hypertension 6h after ingesting approximately 60 capsules of sibutramine. The woman developed the clinical...
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Gene Expression Profiling in C57BL/6 Mice Treated with the Anorectic Drugs Sibutramine and Phendimetrazine and Their Mechanistic Implications

Ko MJ, Choi HS, Ahn JI, Kim SY, Jeong HS, Chung HJ

  • KMID: 2166406
  • Genomics Inform.
  • 2008 Sep;6(3):117-125.
Recently, obesity has become a worldwide public health concern and the use of anorectic drugs has drastically increased. In this study, sibutramine and phendimetrazine, representative marketed anorectics, were repeatedly administered...
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Double-blind, Randomized, Multi-center, Comparative Clinical Trial of Sibutramine Mesilate with Sibutramine Hydrochloride for Evaluating Efficacy and Safety in Obese Patients

Park HS, Kim KS, Kim BT, Lee KW, Ahn CW, Choi WH

  • KMID: 1485447
  • Korean J Obes.
  • 2008 Jun;17(2):82-90.
BACKGROUND: Sibutramine is an anti-obesity agent that inhibits reuptake of serotonin and norepinephrine. The aim of this study is to compare the efficacy and safety of sibutramine mesilate with sibutramine...
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