- The Inhibitory Effect of Curcumin on the Growth of Human Colon Cancer Cells (HT-29, WiDr) in vitro
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Kim KH, Park HY, Nam JH, Park JE, Kim JY, Park MI, Chung KO, Park KY, Koo JY
- KMID: 772765
- Korean J Gastroenterol.
- 2005 Apr;45(4):277-284.
BACKGROUND/AIMS: The effects of curcumin on the growth of human colon cancer cell lines, HT-29 and WiDr cells were examined and the effects of 5-fluorouracil (5-FU) were also studied.... -
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- Curcumin reduces cold storage-induced damage in human cardiac myoblasts
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Abuarqoub , Green CJ, Foresti R, Motterlini R
- KMID: 1094654
- Exp Mol Med.
- 2007 Apr;39(2):139-148.
Curcumin is a polyphenolic compound possessing interesting anti-inflammatory and antioxidant properties and has the ability to induce the defensive protein heme oxygenase-1 (HO-1). The objective of this study was to... -
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- Effect of curcumin on the interaction between androgen receptor and Wnt/beta-catenin in LNCaP xenografts
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Hong JH, Lee G, Choi HY
- KMID: 2344105
- Korean J Urol.
- 2015 Sep;56(9):656-665.
- doi: 10.4111/kju.2015.56.9.656
PURPOSE: Curcumin is a nontoxic, chemopreventive agent possessing multifaceted functions. Our previous study showed that curcumin inhibits androgen receptor (AR) through modulation of Wnt/beta-catenin signaling in LNCaP cells. Therefore, we... -
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- Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits
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Pavithra B, Prakash N, Jayakumar
- KMID: 1726900
- J Vet Sci.
- 2009 Dec;10(4):293-297.
- doi: 10.4142/jvs.2009.10.4.293
Investigation was carried out in adult New Zealand white rabbits to study the influence of curcumin pre-treatment on pharmacokinetic disposition of norfloxacin following single oral administration. Sixteen rabbits were divided... -
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- Therapeutic effect of topical application of curcumin during treatment of radiation burns in a mini-pig model
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Kim J, Park S, Jeon BS, Jang WS, Lee SJ, Son Y, Rhim KJ, Lee SI, Lee SS
- KMID: 2412598
- J Vet Sci.
- 2016 Dec;17(4):435-444.
- doi: 10.4142/jvs.2016.17.4.435
Curcumin protects the skin against radiation-induced epidermal damage and prevents morphological changes induced by irradiation skin, thereby maintaining the epidermal thickness and cell density of basal layers. In this study,... -
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- Curcumin inhibits cellular condensation and alters microfilament organization during chondrogenic differentiation of limb bud mesenchymal cells
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Kim D, Kim SJ, Kang SS, Jin EJ
- KMID: 756209
- Exp Mol Med.
- 2009 Sep;41(9):656-664.
- doi: 10.3858/emm.2009.41.9.072
Curcumin is a well known natural polyphenol product isolated from the rhizome of the plant Curcuma longa, anti-inflammatory agent for arthritis by inhibiting synthesis of inflammatory prostaglandins. However, the mechanisms... -
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- Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets
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Cho JW, Park K, Kweon GR, Jang BC, Baek WK, Suh MH, Kim CW, Lee KS, Suh SI
- KMID: 1056230
- Exp Mol Med.
- 2005 Jun;37(3):186-192.
Ultraviolet B (UVB) irradiation of skin induces an acute inflammation. Cyclooxygenase-2 (COX-2) protein plays key roles in acute inflammation in UVB-irradiated keratinocyte cell line HaCaT. Recently, curcumin has been regarded... -
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- Protective Effects of Curcumin on Renal Oxidative Stress and Lipid Metabolism in a Rat Model of Type 2 Diabetic Nephropathy
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Kim BH, Lee ES, Choi R, Nawaboot J, Lee MY, Lee EY, Kim HS, Chung CH
- KMID: 2374087
- Yonsei Med J.
- 2016 May;57(3):664-673.
- doi: 10.3349/ymj.2016.57.3.664
PURPOSE: Diabetic nephropathy is a serious complication of type 2 diabetes mellitus, and delaying the development of diabetic nephropathy in patients with diabetes mellitus is very important. In this study,... -
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