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Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice

Prasad S, Tyagi AK, Aggarwal B

  • KMID: 2167649
  • Cancer Res Treat.
  • 2014 Jan;46(1):2-18.
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral, and antibacterial activities as indicated by over 6,000...
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Curcumin, COX-2, and Protein p300/CBP

Jung KT, Lim KJ

No abstract available.
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Curcumin and Its Emerging Role in Pain Modulation and Pain Management

Kapoor S

No abstract available.
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Effect of Curcumin on Cancer Invasion and Matrix Metalloproteinase-9 Activity in MDA-MB-231 Human Breast Cancer Cell

Bang MH, Kim WK

  • KMID: 2270062
  • Korean J Nutr.
  • 2006 Dec;39(8):756-761.
Curcumin has been known for its anti-proliferative and apoptotic effects on several cancer cells. We examined the inhibitory effects of curcumin on cancer cell adhesion, motility, invasion and matrix metalloproteinase-9...
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The Effect of Curcumin on Breast Cancer Cells

Liu D, Chen Z

Curcumin, which is extracted from the plant Curcuma longa, has been used in the therapeutic arsenal for clinical oncology. Curcumin has chemopreventive and antitumoral activities against some aggressive and recurrent...
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Curcumin-Induced Autophagy Augments Its Antitumor Effect against A172 Human Glioblastoma Cells

Lee JE, Yoon SS, Moon EY

Glioblastoma is the most aggressive common brain tumor in adults. Curcumin, from Curcuma longa, is an effective antitumor agent. Although the same proteins control both autophagy and cell death, the...
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Effects of Curcumin on Apoptosis in SW480 Human Colon Cancer Cell Line

Choi OS, Kim WK

  • KMID: 2269720
  • Korean J Nutr.
  • 2004 Jan;37(1):31-37.
Curcumin, a natural compound extracted from rhizomes of Curcuma longa, has been shown to possess potent antiinflammatory and anti-tumor activity. The mechanism by which curcumin initiates apoptosis remains poorly understood....
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Estimation of curcumin intake in Korea based on the Korea National Health and Nutrition Examination Survey (2008-2012)

Kwon Y

BACKGROUND/OBJECTIVES: Turmeric and its active component curcumin have received considerable attention due to their many recognized biological activities. Turmeric has been commonly used in food preparation and herbal remedies in...
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The effect of intrathecal curcumin on mechanical allodynia in rats after L5 spinal nerve ligation

Lee JH, Kim YD, Jung HC, Cheong YK

No abstract available.
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The Effect of Curcumin and Human Adipose-derived Stromal Cells on Wound Healing of Lewis Rats

Paik HW, Hwang DY, Yoo G, Byeon JH

  • KMID: 2322225
  • J Korean Soc Plast Reconstr Surg.
  • 2010 Mar;37(2):110-114.
PURPOSE: On this study, we investigated the effects of curcumin and adipose-derived stromal cells(ADSCs) in wound healing process, especially in the aspect of synergic effects when they were administrated simultaneously. METHODS:...
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Analgesic Effects of Intrathecal Curcumin in the Rat Formalin Test

Han YK, Lee SH, Jeong HJ, Kim MS, Yoon MH, Kim WM

BACKGROUND: Curcumin has been reported to have anti-inflammatory, antioxidant, antiviral, antifungal, antitumor, and antinociceptive activity when administered systemically. We investigated the analgesic efficacy of intrathecal curcumin in a rat model...
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The Inhibitory Effect of Curcumin on the Growth of Human Colon Cancer Cells (HT-29, WiDr) in vitro

Kim KH, Park HY, Nam JH, Park JE, Kim JY, Park MI, Chung KO, Park KY, Koo JY

  • KMID: 772765
  • Korean J Gastroenterol.
  • 2005 Apr;45(4):277-284.
BACKGROUND/AIMS: The effects of curcumin on the growth of human colon cancer cell lines, HT-29 and WiDr cells were examined and the effects of 5-fluorouracil (5-FU) were also studied....
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Antipruritic effect of curcumin on histamine-induced itching in mice

Lee HK, Park SB, Chang SY, Jung SJ

Itching is a common clinical symptom of skin disease that significantly affects a patient's quality of life. Transient receptor potential vanilloid 1 (TRPV1) receptors of keratinocytes and peripheral nerve fibers...
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Effect of Curcumin in a Mouse Model of Oxygen-Induced Retinopathy

Kim SJ, Gu YR, Kim YJ, Yu HG

  • KMID: 2338487
  • J Korean Ophthalmol Soc.
  • 2013 Oct;54(10):1588-1593.
PURPOSE: To investigate the effect of curcumin, known to inhibit hypoxia-inducible factor-1, on retinal neovascularization in a mouse model of oxygen-induced retinopathy (OIR). METHODS: OIR was induced by exposing C57BL/6 mice...
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Curcumin Ameliorates Functional and Structural Abnormalities in Cisplatin-induced Neuropathy

Agthong S, Kaewsema A, Charoensub T

Peripheral neuropathy is one of the major side effects of cisplatin; however, effective treatments are lacking. Curcumin is a polyphenol found in the root of Curcuma longa and has been...
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Hypocholesterolemic effects of curcumin via up-regulation of cholesterol 7a-hydroxylase in rats fed a high fat diet

Kim M, Kim Y

  • KMID: 2313443
  • Nutr Res Pract.
  • 2010 Jun;4(3):191-195.
There is an increasing interest in curcumin (Curcuma longa L.) as a cardiovascular disease (CVD) protective agent via decreased blood total cholesterol and low-density lipoprotein-cholesterol (LDL-cholesterol) level. The aim of...
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Differential expression of spinal γ-aminobutyric acid and opioid receptors modulates the analgesic effects of intrathecal curcumin on postoperative/inflammatory pain in rats

Ju J, Shin JY, Yoon JJ, Yin M, Yoon MH

BACKGROUND: Curcumin is traditionally used as an herbal medicine. We explored the efficacy of intrathecal curcumin in relieving both postoperative and inflammatory pain and elucidated the mechanisms of action of...
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Inhibitory effects of curcumin on passive cutaneous anaphylactoid response and compound 48/80-induced mast cell activation

Choi YH, Yan GH, Chai OH, Song CH

Mast cells participate in allergies and inflammation by secreting a variety of pro-inflammatory mediators. Curcumin, the active component of turmeric, is a polyphenolic phytochemical with anti-tumor, anti-inflammatory, anti-oxidative, and anti-allergic...
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Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes

He P, Tian N

Curcumin, an active ingredient of Curcuma longa L., can reduce the concentration of low-density lipoproteins in plasma, in different ways. We had first reported that curcumin exhibits hypocholesterolemic properties by...
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Curcumin utilizes the anti-inflammatory response pathway to protect the intestine against bacterial invasion

Cho JA, Park E

BACKGROUND/OBJECTIVES: Curcumin, a major component of the Curcuma species, contains antioxidant and anti-inflammatory properties. Although it was found to induce apoptosis in cancer cells, the functional role of curcumin as...
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