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The inhibitory effects of recombinant plasminogen kringle 1-3 on the neovascularization of rabbit cornea induced by angiogenin, bFGF, and VEGF

Kim JH, Kim JC, Shin SH, Chang SI, Lee HS, Chung SI

  • KMID: 1029928
  • Exp Mol Med.
  • 1999 Dec;31(4):203-209.
Angiostatin is a potent angiogenesis inhibitor that is composed of the first four kringles of plasminogen fragment. Angiostatin with one less kringle molecule (kringle 1 to 3) was...
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Effect of FK 506 on the cornea: use of topical FK 506 in corneal transplantation in a guinea pig-rat model

Tchah H, Lim B

To evaluate the effect of different concentrations 0.03%, 0.1% and 0.3% of FK 506 on xenograft corneal rejection, guinea pig corneas were transplanted into rats. FK 506 was then applied...
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The Changes in Corneal Astigmatism after Botulinum Toxin-A Injection in Patients with Blepharospasm

Moon NJ, Lee HI, Kim JC

To determine if the involuntary contractions of eyelids may have any effects on the development of corneal astigmatism, we performed this prospective study which includes 19 patients with either essential...
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Vortex Keratopathy in a Patient Receiving Vandetanib for Non-Small Cell Lung Cancer

Ahn J, Wee WR, Lee JH, Hyon JY

We report a case of vortex keratopathy in a patient treated with vandetanib for non-small cell lung cancer (NSCLC). A 44-year-old female who underwent two cycles of chemotherapy for NSCLC...
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Gintonin, an exogenous ginseng-derived LPA receptor ligand, promotes corneal wound healing

Kim HJ, Kim JY, Lee BH, Choi SH, Rhim H, Kim HC, Ahn SY, Jeong SW, Jang M, Cho IH, Nah SY

Ginseng gintonin is an exogenous ligand of lysophosphatidic acid (LPA) receptors. Accumulating evidence shows LPA helps in rapid recovery of corneal damage. The aim of this study was to evaluate...
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Microarray for Genes Associated with Signal Transduction in Diabetic OLETF Keratocytes

Lee JE, Lee JS, Hwang SH

PURPOSE: The purpose of this study was to identify differences in signal transduction gene expression between normal and diabetic keratocytes stimulated with interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha). ...
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Epithelial Wound Healing after Cataract Surgery Comparing Two Different Topical Fluoroquinolones

Han KE, Chung WS, Kim TI, Kim S, Kim T, Kim EK

PURPOSE: To compare the epithelial wound healing response of two preservative-free fluoroquinolones, moxifloxacin and levofloxacin, in patients who underwent cataract surgery. MATERIALS AND METHODS: In this prospective, evaluator-masked, randomized clinical trial,...
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