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Depression of Ca2+ influx in complement C5a-stimulated neutrophils by calmodulin inhibitors

Ham DS, Kim HH, Han ES, Lee CS

  • KMID: 2071531
  • Korean J Physiol Pharmacol.
  • 1998 Feb;2(1):109-117.
Role of Ca2+/calmodulin complex in intracellular Ca2+ mobilization in neutrophils has not been clearly elucidated. In this study, effects of chlorpromazine, trifluoperazine and imipramine on the intracellular Ca2+ mobilization, including Ca2+ influx, in...
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Yersinia enterocolitica Exploits Signal Crosstalk between Complement 5a Receptor and Toll-like Receptor 1/2 and 4 to Avoid the Bacterial Clearance in M cells

Kim SH, Jang YS

In the intestinal mucosal surface, microfold cells (M cells) are the representative gateway for the uptake of luminal antigens. At the same time, M cells are the primary infection site...
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Acute Pancreatitis with Purtscher's-like Retinopathy

Han JS, Nam SE, Jang DK, Lee JK

A 28-year-old man with a history of alcohol abuse was diagnosed with acute pancreatitis based on clinical symptoms, laboratory findings and computed tomography findings. On the second day of hospitalization,...
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Molecular targeted therapies for microscopic polyangiitis and granulomatosis with polyangiitis

Harigai M, Tsutsumino M, Takada H, Nagasaka K

Clinical trials and observational studies have established cyclophosphamide (CY) or rituximab plus glucocorticoid (GC) as standard remission induction therapies in patients with microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA)....
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Tetrachloroauric acide depresses the activation processes of phagocytic cells

Lee CS

  • KMID: 1849846
  • Korean J Physiol Pharmacol.
  • 1998 Jun;2(3):377-384.
Gold compounds depress phagocytic cell responses, including chemotaxis, and respiratory burst. However, the effects of gold compounds on the function of phagocytic cells are variable according to the preparation of medicine. In this...
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