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Adjuvant Effect of IV Clodronate on the Delay of Bone Metastasis in High-Risk Prostate Cancer Patients: A Prospective Study

Rodrigues , Hering FO, Meller A

  • KMID: 2167565
  • Cancer Res Treat.
  • 2011 Dec;43(4):231-235.
PURPOSE: High-risk prostate cancer patients undergoing treatment often experience biochemical recurrence. The use of bisphosphonates as an adjuvant treatment delays skeletal events, yet whether or not bisphosphonates also delay metastastic...
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An Important Role of Macrophages for Wound Margin Regeneration in a Murine Flap Model

Won HR, Seo C, Lee HY, Roh J, Kim CH, Jang JY, Shin YS

BACKGROUND: Macrophages have been known to have diverse roles either after tissue damage or during the wound healing process; however, their roles in flap wound healing are poorly understood. In...
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Macrophage Depletion by Clodronate Liposomes Suppresses Neointimal Formation After Carotid Artery Injury in Apolipoprotein E-Deficient Mice

Hong SJ, Ahn TH, Shim WJ, Park SM, Choi JI, Park JS, Lim SY, Lim DS, Park CG, Seo HS

BACKGROUND AND OBJECTIVES: Clodronate liposomes deplete phagocytic cells, thereby suppressing inflammation after vascular injury. We compared the effect of clodronate liposomes on macrophage depletion and neointimal formation in apolipoprotein E-deficient...
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The investigation of macrophage infiltration in the early phase of ischemic acute renal failure in mice

Yu SJ, Oh DJ, Yu SH

BACKGROUND/AIMS: Inflammation plays a key role in ischemic acute renal failure (ARF). The present study investigated the infiltration of macrophages in the early phase of ischemic ARF in mice....
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