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Is the impact of childhood vaccines on coronavirus disease 2019, which is moderate in pediatric patients, possible?

Bozkurt HB

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Vaccines in the United States: a systematic review on history of evolution, regulations, licensing, and future challenges

Sathyanarayana SD, Fernandes SD, Castelino LJ, Vadakkepushpakath AN, Shriramh RG

Vaccines are credited with reducing or effectively eradicating a number of infectious diseases such as smallpox, measles, and diphtheria. Particularly in nations like the United States, where a large number...
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Coronavirus epitope prediction from highly conserved region of spike protein

Yurina V

Purpose: The aim of this research was to predict the epitope for coronavirus family spike protein. Coronavirus family is highly evolved viruses which cause several outbreaks in the past decades. Therefore,...
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An edible vaccine development for coronavirus disease 2019: the concept

Sohrab SS

A novel coronavirus was emerged in December 2019 from Wuhan city, China and has now become a global threat to human health. Currently, the coronavirus disease 2019 (COVID-19) has spread...
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Gemini lipopeptides as vaccine adjuvants: a new role for these versatile carriers

Grippo LD, Reidel IG, García MI, Streu A, Müller DM, Veaute CM

The design of subunit vaccines requires new adjuvant systems. We designed and synthesized new lipopeptides (cysteine-based) of low molecular weight with different hydrophobic chains that dimerize becoming Gemini lipopeptides. They...
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Genotype-specific neutralizing antibody titers against Japanese encephalitis virus genotypes 1 and 3 in horses immunized with a genotype 3 vaccine

Kim HH, Yang DK, Ji M, Lee SK, Hyun BH

Purpose: Japanese encephalitis is one of the most important mosquito-borne and zoonotic diseases in Asia and the Pacific region. Although the dominant Japanese encephalitis virus (JEV) genotype has shifted from...
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Preparation and efficacy of freeze-dried inactivated vaccine against bovine viral diarrhea virus genotypes 1 and 2, bovine herpes virus type 1.1, bovine parainfluenza-3 virus, and bovine respiratory syncytial virus

El Fadeel MRA, El-Dakhly AT, Allam AM, Farag TK, El-kholy AAM

Purpose: Bovine respiratory disease is a worldwide health concern in the feedlot cattle causing morbidity and mortality in young with major economic losses to the producer. Programs of vaccination are...
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Bluetongue virus viral protein 7 stability in the presence of glycerol and sodium chloride

Russell BL, Gildenhuys S

Purpose: The Orbivirus Bluetongue virus (BTV) is an economically significant disease that affects mainly wild and domestic ruminants. BTV is most often seen symptomatically in sheep, but is easily carried...
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Potential use of 3-(trimethoxysilyl)propyldimethyl octadecyl ammonium chloride as an antimicrobial and antiviral agent for the disinfection of personal protective equipment

Kim Y, Youn H, Kim J, Lee D, Go S, Park Je, Lee S, Noh J, Nahm SS

Currently, no vaccine or established therapeutic agents are available for coronavirus disease 2019. The sharp increase in demand for personal protective equipment (PPE) necessitates an improvement in the protective efficacy...
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Determination of non-structural protein level for Turkey foot-and-mouth disease vaccine antigens during in-process

Sareyyüpoğlu B, Çokçalışkan C, Çoskuner A, Gülyaz V

Purpose: The success of foot-and-mouth disease (FMD) serological serosurveillance greatly depends on the FMD vaccine which does not include any non-structural proteins (NSPs) of the FMD virus. Since pure FMD...
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Current national policies for infant universal bacille CalmetteGuérin vaccination were associated with lower mortality from coronavirus disease 2019

Ebina-Shibuya R, Horita N, Namkoong H, Kaneko T

An exciting debate has emerged whether bacille Calmette-Guérin (BCG) vaccination is effective for the coronavirus disease 2019 (COVID-19) pandemic. Some advocated that BCGvaccinated people are less suffered from the virus...
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Antigenic properties of dense granule antigen 12 protein using bioinformatics tools in order to improve vaccine design against Toxoplasma gondii

Ghaffari AD, Dalimi A, Ghaffarifar F, Pirestani M

Purpose: Toxoplasma gondii is an opportunistic parasite infecting all warm-blooded animals including humans. The dense granule antigens (GRAs) play an important role in parasite survival and virulence and in forming...
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In-depth computational analysis of calcium-dependent protein kinase 3 of Toxoplasma gondii provides promising targets for vaccination

Majidiani H, Soltani S, Ghaffari AD, Sabaghan M, Taghipour A, Foroutan M

Purpose: The Toxoplasma gondii calcium-dependent protein kinase-3 (CDPK3) is a key enzyme for parasite egress, control of calcium-dependent permeabilization in parasitophorous vacuole membrane and tissue cyst formation. In this study,...
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Influence of temperature on the antigenic changes of virus-like particles

Shin Ji, Park YC, Song JM

Purpose: In this study, we investigated whether the antigenic changes of the virus-like particles (VLPs) are affected by the temperature during storage. Materials and Methods: After exposing the recombinant influenza VLPs...
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Investigation of adverse events following bacille CalmetteGuérin immunization using immunization safety surveillance system in Korea Centers for Disease Control and Prevention

Roh EJ, Lee YK, Lee MH, Kim MK, Kim TE, Lee SG, Chung EH

Purpose: The report of adverse events following immunization (AEFI) in Korea has continued since 1994, and the most frequently reported cases of AEFI of Korea Centers for Disease Control and...
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Autolysin (lytA) recombinant protein: a potential target for developing vaccines against pneumococcal infections

Afshar D, Rafiee F, Kheirandish M, Moghadam SO, Azarsa M

Purpose: N-acetylmuramoyl-l-alanine amidase known as lytA, is an immunogenic protein that plays an important role in the pathogenesis of Streptococcus pneumoniae. It is highly conserved among S. pneumoniae strains and...
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