- Correlation of Decreased Expressions of Claudin 4 and E-cadherin Proteins and the Clinicopathologic Factors of Stomach Cancer
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Lee SM, Lee JH, Kim BG, Kim YS, Park YG, Chi KC, Lim HM, Kim SJ
- KMID: 2211100
- J Korean Surg Soc.
- 2007 Sep;73(3):221-226.
PURPOSE: We examined the expressions of claudin-4 and E-cadherin, which are known as cell adhesion-associated proteins, in stomach cancer. The relationship of their expression with the clinicopathologic factors was examined... -
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- Expression of Claudin-1 and -4 in Benign Lesions and Invasive Ductal Carcinomas of the Breast
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Choi HJ, Jung JH, Yoo J, Kang SJ, Lee KY
- KMID: 1521637
- Korean J Pathol.
- 2007 Aug;41(4):232-237.
BACKGROUND: The claudins are a family of transmembrane proteins associated with tight junctions and they are critical for maintaining cell-to-cell adhesion in sheets of epithelial cells. However, their role in... -
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- Expression of claudin-1, claudin-4 and zonula occludens-1 in cervical intraepithelial neoplasia and invasive squamous cell carcinoma
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Lee SK, Rho HK, Park TY, Kang KH, Cho TI, Lee TJ
- KMID: 2077793
- Korean J Obstet Gynecol.
- 2007 Oct;50(10):1378-1385.
OBJECTIVE: Cell to cell and cell to extracellular matrix interaction are crucial in tumor development and progression. Tight junction proteins such as claudins and zonula occludens-1 (ZO-1) play an important... -
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- Alteration in Claudin-4 Contributes to Airway Inflammation and Responsiveness in Asthma
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Lee PH, Kim BG, Lee SH, Lee JH, Park SW, Kim DJ, Park CS, Leikauf GD, Jang AS
- KMID: 2428847
- Allergy Asthma Immunol Res.
- 2018 Jan;10(1):25-33.
- doi: 10.4168/aair.2018.10.1.25
PURPOSE: Claudin-4 has been reported to function as a paracellular sodium barrier and is one of the 3 major claudins expressed in lung alveolar epithelial cells. However, the possible role... -
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- Prognostic Significance of Claudin 4 in Completely Resected Adenocarcinoma of the Lung
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Chae MC, Park CK, Keum DY, Hwang I, Kwon KY, Jang BC
- KMID: 2288790
- Korean J Thorac Cardiovasc Surg.
- 2014 Jun;47(3):262-268.
BACKGROUND: The development of diagnostic techniques and an awareness of health examinations can bring about an early diagnosis of lung cancer. However, appropriate postoperative management and adjuvant chemotherapy remain under... -
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- Acute Modulations in Stratum Corneum Permeability Barrier Function Affect Claudin Expression and Epidermal Tight Junction Function via Changes of Epidermal Calcium Gradient
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Baek JH, Lee SE, Choi KJ, Choi EH, Lee SH
- KMID: 1503920
- Yonsei Med J.
- 2013 Mar;54(2):523-528.
- doi: 10.3349/ymj.2013.54.2.523
Tight junction (TJ) is recognized as a second barrier of the skin. Altered expression of TJ proteins in various skin diseases characterized by the abnormal permeability barrier such as psoriasis... -
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- Comparison of Tight Junction Protein-Related Gene mRNA Expression Levels between Male and Female Gastroesophageal Reflux Disease Patients
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Kim JJ, Kim N, Park JH, Kim YS, Lee SM, Lee DH, Jung HC
- KMID: 2417307
- Gut Liver.
- 2018 Jul;12(4):411-419.
- doi: 10.5009/gnl17419
BACKGROUND/AIMS: Male predominance has been observed in the erosive reflux disease (ERD), but reverse finding in nonerosive reflux disease (NERD). This suggests sex-specific medicine approach is needed but its mechanism... -
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- TNF-alpha Downregulates E-cadherin and Sensitizes Response to gamma-irradiation in Caco-2 Cells
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Yi JY, Jung YJ, Choi SS, Chung E
- KMID: 2128578
- Cancer Res Treat.
- 2009 Sep;41(3):164-170.
PURPOSE: The purpose of the present study was to assess the biological effects of TNF-alpha in Caco-2 well-differentiated colon adenocarcinoma cells and to determine radiation sensitivity in order to develop... -
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- A Prospective Study of Eosinophilic Esophagitis and the Expression of Tight Junction Proteins in Patients with Gastroesophageal Reflux Disease Symptoms
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Okimoto K, Arai M, Ishigami H, Saito K, Minemura S, Maruoka D, Matsumura , Nakagawa T, Katsuno T, Suzuki M, Nakatani Y, Yokosuka O
- KMID: 2404714
- Gut Liver.
- 2018 Jan;12(1):30-37.
- doi: 10.5009/gnl16600
BACKGROUND/AIMS: Eosinophilic esophagitis (EoE) is often erroneously diagnosed as gastroesophageal reflux disease (GERD). The aim of this study is to investigate the prevalence of EoE and the expression of tight... -
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- Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model
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Song CH, Kim N, Sohn SH, Lee SM, Nam RH, Na HY, Lee DH, Surh YJ
- KMID: 2427459
- Gut Liver.
- 2018 Nov;12(6):682-693.
- doi: 10.5009/gnl18221
BACKGROUND/AIMS: Intestinal barrier dysfunction is a hallmark of inflammatory bowel diseases (IBDs) such as ulcerative colitis. This dysfunction is caused by increased permeability and the loss of tight junctions in... -
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