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Effect of Bile Acids on Biliary Excretion of Cholesterol in Rabbits

Hong SS, Kim KH, Kim WJ

  • KMID: 2439778
  • Yonsei Med J.
  • 1973 Dec;14(1):109-115.
The effects of cholic acid and eight related cholanic acid analogs on bile flow and biliary excretion of bile salts and cholesterol were studied in rabbits. Bile acids were infused...
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Inhibition of expression of P-selectin by antioxidant in cholesterol-fed rats

Lee CS, Choi JM, Park DH, Kang DY, Register T, Adams MR

Butylated hydroxytoluene (BHT) can inhibit experimental atherosclerosis in animals. Although the agent is an antioxidant, the exact mechanism of the reaction in atherosclerosis is still unknown. To investigate the effects...
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Induction of tissue inhibitor of matrix metalloproteinase-2 by cholesterol depletion leads to the conversion of proMMP-2 into active MMP-2 in human dermal fibroblasts

Kim S, Oh JH, Lee Y, Lee J, Cho KH, Chung JH

Cholesterol is one of major components of cell membrane and plays a role in vesicular trafficking and cellular signaling. We investigated the effects of cholesterol on matrix metalloproteinase-2 (MMP-2) activation...
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Sterol-independent repression of low density lipoprotein receptor promoter by peroxisome proliferator activated receptor gamma coactivator-1alpha (PGC-1alpha)

Jeong JH, Cho S, Kim Pak Y

Peroxisome proliferator activated receptor (PPAR) gamma coactivator-1alpha (PGC-1alpha) may be implicated in cholesterol metabolism since PGC-1alpha co-activates estrogen receptor alpha (ERalpha) transactivity and estrogen/ERalpha induces the transcription of LDL receptor...
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Down-regulation of ATP-binding cassette transporter G1 expression by unmethylated CpG oligodeoxynucleotides in RAW 264.7 macrophages

Seo JM, Lee JY, Ji GE, You JC

We have investigated the effect of various forms of phosphodiester cytidine-phosphate-guanosine oligodeoxynucleotides (CpG ODNs) on the production of pro-inflammatory cytokines and related genes in RAW 264.7 macrophages. Treatment with the...
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Annexin A6 is highly abundant in monocytes of obese and type 2 diabetic individuals and is downregulated by adiponectin in vitro

Stogbauer , Weigert J, Neumeier M, Wanninger , Sporrer D, Weber M, Schaffler , Enrich C, Wood P, Grewal T, Aslanidis , Buechler C

Adiponectin stimulates cholesterol efflux in macrophages and low adiponectin may in part contribute to disturbed reverse cholesterol transport in type 2 diabetes. Monocytes express high levels of annexin A6 that...
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Hypocholesterolemia in Patients with an Amebic Liver Abscess

Flores MS, Obregon-Cardenas A, Tamez E, Rodriguez , Arevalo K, Quintero I, Tijerina R, Bosques F, Galan L

  • KMID: 1792365
  • Gut Liver.
  • 2014 Jul;8(4):415-420.
BACKGROUND/AIMS: Many parasites induce changes in the lipid profiles of the host. Cholesterol increases the virulence of Entamoeba histolytica in animal models and in vitro culture. This study aimed to...
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Does Waist Indicate Dyslipidemia better than BMI in Korean Adult Population?

Jeong SK, Seo MW, Kim YH, Kweon SS, Nam HS

Obesity is an independent and modifiable risk factor for cardiovascular disease, and known as a core of the metabolic syndrome. Obesity has been largely diagnosed based upon anthrompometric measurements like...
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Effect of cholestyramine on the formation of pigment gallstone in high carbohydrate diet-fed hamsters

Lee YC, Song DK, Kim JS, Choi CS

This study was designed to investigate the effect of cholestyramine on the formation of pigment gallstones in high carbohydrate diet-fed hamsters and whether that effect occurred because of cholecystokinin action....
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Prevalence of and Risk Factors for Atrial Fibrillation in Korean Adults Older than 40 Years

Jeong JH

Atrial fibrillation (AF) is a common arrhythmia that is a potent independent risk factor for stroke. The incidence of AF increase with age and most affected people have underlying cardiac...
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A point mutant of apolipoprotein A-I, V156K, exhibited potent anti-oxidant and anti-atherosclerotic activity in hypercholesterolemic C57BL/6 mice

Cho KH, Park SH, Han JM, Kim HC, Chung YJ, Choi I, Kim JR

  • KMID: 1094656
  • Exp Mol Med.
  • 2007 Apr;39(2):160-169.
In our previous study, two point mutants of apolipoprotein A-I, designated V156K and A158E, revealed peculiar characteristics in their lipid-free and lipid-bound states. In order to determine the putative therapeutic...
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Exendin-4 improves resistance to Listeria monocytogenes infection in diabetic db/db mice

Liu HY, Chung CY, Yang WC, Liang CL, Wang CY, Chang CY, Chang CL

The incidence of diabetes mellitus is increasing among companion animals. This disease has similar characteristics in both humans and animals. Diabetes is frequently identified as an independent risk factor for...
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