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What should we consider in mixed chimerism after hematopoietic stem cell transplantation?

Lim J

No abstract available.
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Mixed chimerism after hemopoietic stem cell transplantation

Kim BK

  • KMID: 2251309
  • Korean J Med.
  • 2000 Apr;58(4):371-373.
No abstract available.
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A Case of DNA Chimerism Analysis as a Marker of Donor Lymphocyte Infusion

Kim TY, Park SH, Suh JS, Sohn SK

  • KMID: 2143336
  • Korean J Hematol.
  • 2001 Nov;36(4):342-345.
Donor lymphocyte infusion (DLI) has some benefit effects as graft-versus-leukemia effect, reducing the relapse of leukemia and inducing of a complete remission. But it has also a graft-versus-host-disease (GVHD) effect....
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Clinical Significance of Mixed Chimerism after Hematopoietic Stem Cell Transplantation

Huh HJ, Huh JW, Kang ES, Jeong GY, Lee M, Seong CM, Chung WS

  • KMID: 2239636
  • Korean J Lab Med.
  • 2002 Dec;22(6):441-446.
BACKGROUND: Chimerism analysis used to be one of the most valuable methods for monitoring patients after allogeneic hematopoietic stem cell transplantation (SCT). The relationship between the mixed chimerism status and...
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Lineage-specific chimerism analysis in nucleated cells, T cells and natural killer cells after myeloablative allogeneic hematopoietic stem cell transplantation

Goh RY, Kim SH, Han JY

BACKGROUND: Chimerism analysis is an important tool for assessing the origin of hematopoietic cells after allogeneic stem cell transplantation (allo-SCT) and can be used to detect impending graft rejection and...
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Clinical Utility of Chimerism Status Assessed by Lineage-Specific Short Tandem Repeat Analysis: Experience from Four Cases of Allogeneic Stem Cell Transplantation

Goh RY, Cho SS, Song YJ, Heo K, Oh SY, Kim SH, Kwon HC, Kim HJ, Han JY

Chimerism testing permits early prediction and documentation of successful engraftment, and also facilitates detection of impending graft rejection. In this study, we serially monitored chimerism status by short tandem repeat-based...
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Blood Chimerism in a Dizygotic Dichorionic Pregnancy

Jang JH, Jung H, Kim JH, Park WS, Kim SH

Blood chimerism in twins is known to occur through the transfer of hematopoietic stem cells between the fetuses via a common placenta. We present a case of blood chimerism in...
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Clinical implications of chimerism after allogeneic hematopoietic stem cell transplantation in children with non-malignant diseases

Park M, Koh KN, Seo JJ, Im HJ

BACKGROUND: The effects of chimerism on outcomes following allogeneic hematopoietic stem cell transplantation (HSCT) are unclear and may differ between diseases. We retrospectively evaluated the association between chimerism and transplant...
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The Discrimination Power and Effectiveness of 3 Kinds of LTR Primers in the VNTR-PCR for Evaluation of the Engraftment of Allogeneic Peripheral Blood Stem Cells Transplantation

Kim TY, Park SH, Kwon EH, Kim KY, Suh JS, Sohn SK

  • KMID: 2089690
  • Korean J Clin Pathol.
  • 2001 Dec;21(6):527-533.
BACKGROUND: There are highly-polymorphic DNA markers in the human genomic DNA, known as the variable number of tandem repeats (VNTR). The VNTR markers can be used to evaluate the engraftment...
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Detection of Mixed Chimerism after Sex-Mismatched Bone Marrow Transplantation Using Fluorescence in situ Hybridization: Engraftment and Follow-up Evaluation

Ryang DW, Hong WP, Cho D, Lee JJ, Chung IJ, Cho MK, Kook H, Hwang TJ, Shin JH, Suh SP

  • KMID: 2143370
  • Korean J Hematol.
  • 1999 Aug;34(3):461-470.
BACKGROUND: Interphase fluorescence in situ hybridization (FISH) analysis following sex-mismatched bone marrow transplantation (BMT) is a sensitive and quantitative method to better assess the engraftment state and mixed chimerism. METHODS:...
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Role of Regulatory T Cells in Transferable Immunological Tolerance to Bone Marrow Donor in Murine Mixed Chimerism Model

Yoon IH, Kim YH, Kim YS, Shin JS, Park CG

Constructing a bone marrow chimera prior to graft transplantation can induce donor-specific immune tolerance. Mixed chimerism containing hematopoietic cells of both recipient- and donor-origin has advantages attributed from low dose...
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Chimerism Proven by Flow Cytomety in the Setting of an ABO Discrepancy: A Case Report

Jeong ES, Moon CJ, Cho D, Park JT, Ryang DW

  • KMID: 2300053
  • Korean J Blood Transfus.
  • 2009 Dec;20(3):247-252.
Chimerism is an important, yet uncommon cause of ABO phenotype/genotype discrepancies. The propositus was a 28 year-old pregnant women who had an ABO discrepancy, expressing an A(weak)B RBC phenotype and...
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Impact of Day 14 Peripheral Blood Chimerism after Allogeneic Hematopoietic Stem Cell Bone Transplantation on the Treatment Outcome of Non-Malignant Disease

Choi YB, Lee JW, Sung KW, Koo HH, Kim HJ, Yoo KH

BACKGROUND: The impact of early peripheral blood chimerism on the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is unclear. We aimed to determine whether day 14 peripheral blood chimerism...
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Chimerism by Analysis of PCR of Highly Polymorphic Variable Number of Tandem Repeat (VNTR) DNA Sequences in Human Genome; The Graft Versus Host Disease (GVHD) and Relapse of Leukemia after Allogeneic Bone Marrow Transplantation

Cho CR, Hansen JA, Martin P, Smith A, Urm SH, Kim SJ

  • KMID: 2143364
  • Korean J Hematol.
  • 1999 Aug;34(3):403-415.
No abstract available.
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Practical Evaluation of Engraftment and Mixed Chimerism Using PCR Amplification of a Microsatellite in the Class II Eb Gene in Murine MHC-mismatched, Nonmyeloablative Bone Marrow Transplantation

Roh SY, Park MJ, Park H, Cho SG, Min SY, Lee JW, Min WS, Kim CC, Kim HY, Chang HS

BACKGROUND: Although engraftment following murine allogeneic bone marrow transplantation (BMT) is most commonly confirmed by H2 typing using flow cytometry, recipient mice can be seriously injured during peripheral blood (PB)...
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The Immune Tolerance Effect of Donor Chimerism Induced by Sublethal dose of Radiation on Allogeneic Organ Transplantation

Kim JA, Hong SY, Choi YS, Kim SH, Kim CC

  • KMID: 2252433
  • Korean J Hematol.
  • 2002 Feb;37(1):46-53.
BACKGROUND: Transplantation of solid organs has been increasing explosively. However, numerous problems remain unsolved, including the requirement for chronic immunosuppressive therapy and the shortage of donor organs. Recently one way...
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Effects of mixed chimerism and immune modulation on GVHD, disease recurrence and survival after HLA-identical marrow transplantation for hematologic malignancies

Park SJ, Min WS, Yang IH, Kim HJ, Min CK, Eom HS, Honh HS, Eom KS, Suh JG, Lee JW, Kim CC

  • KMID: 1985202
  • Korean J Med.
  • 2000 Mar;58(3):267-275.
No abstract available.
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Prevention of Allograft Rejection by Immune Tolerance

Lee JS, Kwon B, Cho HR

  • KMID: 2003575
  • J Korean Soc Transplant.
  • 2006 Jun;20(1):1-13.
The development of immunosuprressants has had a significant contribution to inhibition of acute allograft rejection. However, long-term graft survival has not been realized by immunosuppressants, probably because of their nonspecific...
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Clinical Strategies to Develop Transplantation Tolerance

Lee JS, Kwon B, Cho HR

  • KMID: 1512743
  • Hanyang Med Rev.
  • 2006 Aug;26(3):70-76.
The development of immunosuprressants has had a significant influence on inhibition of acute allograft rejection. However, long-term graft survival has not been achieved by immunosuppressants, probably because of their nonspecific...
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T-Cell Chimerism Analysis by Mutiplex STR PCR after Non-Myeloablative Allogeneic Stem Cell Transplantation

Goh RY, Han JY, Han H, Kim JS, Kwon HC, Kim SH, Kim HJ

BACKGROUND: The ability of non-myeloablative allogeneic stem cell transplants to eradicate host neoplastic cells is based on the accumulating evidence of a graft-versus-malignancy (GVM) effect. Stable mixed chimerism (MC) is...
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