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Completion hysterectomy after chemoradiotherapy for locally advanced adeno-type cervical carcinoma: updated survival outcomes and experience in post radiation surgery

Yang J, Yang J, Cao D, Shen K, Ma J, Zhang F

OBJECTIVE: To compare patient survival outcomes between completion hysterectomy and conventional surveillance in locally advanced adenocarcinoma of the cervix after concurrent chemoradiotherapy (CCRT). METHODS: Patients with adenocarcinoma of the cervix after...
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Chemoradiotherapy for Esophageal Cancer

Park MI

Esophageal cancer is a highly lethal malignancy. Squamous cell cancer (SCC) and adenocarcinoma are two major histologic types of esophageal cancer. The therapeutic approaches for both histologic types tend to...
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Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis

Kim HK, Ko WJ, Kwon CI, Song GW, Yoo IK, Song JH, Kim HS, Cho JY

Endoscopic submucosal dissection is recommended as an alternative therapy for early esophageal cancer. However, achieving curative resection in this procedure remains controversial since precise prediction of lymph node metastasis can...
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Chemoradiotherapy versus radiotherapy alone following induction chemotherapy for elderly patients with stage III lung cancer

Kim DY, Song C, Kim SH, Kim YJ, Lee JS, Kim JS

PURPOSE: It is unclear whether adding concurrent chemotherapy (CT) to definitive radiotherapy (RT) following induction CT is a tolerable and cost effective treatment for non-small-cell lung cancer (NSCLC) patients aged...
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Prognostic value of neutrophil-to-lymphocyte ratio in locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy

Park EY, Kim YS, Choi KH, Song JH, Lee HC, Hong SH, Kang JH

PURPOSE: This study aimed to investigate neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as prognostic factors in patients with locally advanced non-small cell lung cancer (NSCLC) who received concurrent chemoradiotherapy...
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Combination Assessment of Clinical Complete Response of Patients With Rectal Cancer Following Chemoradiotherapy With Endoscopy and Magnetic Resonance Imaging

Ko HM, Choi YH, Lee JE, Lee KH, Kim JY, Kim JS

PURPOSE: The response to neoadjuvant chemoradiotherapy (CRT) for rectal cancer can be assessed using digital rectal examination, endoscopy and magnetic resonance imaging (MRI). Precise assessment of clinical complete response (CR)...
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Response Assessment with MRI after Chemoradiotherapy in Rectal Cancer: Current Evidences

Seo N, Kim H, Cho MS, Lim JS

Baseline magnetic resonance imaging (MRI) has become the primary staging modality for surgical plans and stratification of patient populations for more efficient neoadjuvant treatment. Patients who exhibit a complete response...
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A Gastro-Pleuro-Pericardial Fistula That Occurred Following Palliative Chemoradiotherapy for Tongue Cancer: A Case Report

Jang SJ, Cha YK, Kim JS, Kim DY, Kim DB

A gastro-pleuro-pericardial fistula is an abnormal communication between the stomach, pleural cavity, and pericardium. It is a very rare and life-threatening condition, which needs prompt intervention. We report a case...
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Associations of Genetic Variations in Mismatch Repair Genes MSH3 and PMS1 with Acute Adverse Events and Survival in Patients with Rectal Cancer Receiving Postoperative Chemoradiotherapy

Yang J, Huang Y, Feng Y, Li H, Feng T, Chen J, Yin L, Wang W, Wang S, Liu Y, Song Y, Li Y, Jin J, Tan W, Lin D

PURPOSE: Mismatch repair (MMR) deficiency plays a critical role in rectal cancer. This study aimed to explore the associations between genetic variations in seven MMR genes and adverse events (AEs)...
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Impact of Mucin Proportion in the Pretreatment MRI on the Outcomes of Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiotherapy

Kim E, Kim K, Kim SH, Han SW, Kim TY, Jeong SY, Park KJ, Koh J, Kang GH, Chie EK

PURPOSE: The purpose of this study was to evaluate treatment response to neoadjuvant chemoradiotherapy (CRT) with regard to mucin status in pathology and pretreatment magnetic resonance imaging (MRI) in locally...
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Oncologic Outcomes of Postoperative Chemoradiotherapy Versus Chemotherapy Alone in Stage II and III Upper Rectal Cancer

Yoon JE, Lee SY, Kwak HD, Yeom SS, Kim CH, Joo JK, Kim HR, Kim YJ

PURPOSE: The aim of this study was to assess oncological outcomes of postoperative radiotherapy plus chemotherapy (CRT) versus chemotherapy alone (CTx) in stage II or III upper rectal cancer patients...
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Less is more: role of additional chemotherapy to concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal cancer management

Ahn YC

Concurrent chemoradiation therapy (CCRT) has played the most important and central role in the definitive therapy for the patients with locoregionally advanced stage nasopharynx cancer. The addition of induction chemotherapy...
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What are the most important prognostic factors in patients with residual rectal cancer after preoperative chemoradiotherapy?

Kim SM, Yoon G, Seo AN

BACKGROUND: We aimed to establish robust histoprognostic predictors on residual rectal cancer after preoperative chemoradiotherapy (CRT). METHODS: Analyzing known histoprognostic factors in 146 patients with residual disease allows associations with patient...
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Clinical significance of lymph node size in locally advanced cervical cancer treated with concurrent chemoradiotherapy

Oh J, Seol KH, Choi YS, Lee JW, Bae JY

BACKGROUND: This study aimed to assess the in-field lymph node (LN) failure rate according to LN size and to investigate effect of LN size on the survival outcome of patients...
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Adjuvant hysterectomy in patients with locally advanced cervical cancer treated with concurrent chemoradiotherapy

Shim SH

No abstract available.
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EGFR Mutation Is Associated with Short Progression-Free Survival in Patients with Stage III Non-squamous Cell Lung Cancer Treated with Concurrent Chemoradiotherapy

Park SE, Noh JM, Kim YJ, Lee HS, Cho JH, Lim SW, Ahn YC, Pyo H, Choi YL, Han J, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ

PURPOSE: This study was conducted to evaluate the relationship between epidermal growth factor receptor (EGFR) mutation and clinical outcomes in patients with stage III non-squamous cell lung cancer treated with...
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Early Systemic Failure After Preoperative Chemoradiotherapy for the Treatment of Patients With Rectal Cancer

Choi T, Baek SJ, Kwak JM, Kim J, Kim SH

PURPOSE: Distant metastasis can occur early after neoadjuvant chemoradiotherapy (CRT) in patients with rectal cancer. This study was conducted to evaluate the clinical characteristics of patients who developed early systemic...
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Oncologic Outcomes in Patients Who Undergo Neoadjuvant Chemoradiotherapy and Total Mesorectal Excision for Locally Advanced Rectal Cancer: A 14-Year Experience in a Single Institution

Kim MJ, Jeong SY, Park JW, Ryoo SB, Cho SS, Lee KY, Park KJ

PURPOSE: This study evaluated the oncologic outcomes of locally advanced rectal cancer patients who underwent preoperative neoadjuvant chemoradiotherapy (CRT) followed by surgery and determined the prognostic significance of pathologic complete...
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Clinical Outcomes of Patients With Locally Advanced Rectal Cancer With Persistent Circumferential Resection Margin Invasion After Preoperative Chemoradiotherapy

Kim CH, Yeom SS, Kwak HD, Lee SY, Ju JK, Kim YJ, Kim HR

PURPOSE: Treatment after failure of circumferential resection margin (CRM) conversion after preoperative chemoradiotherapy (pCRT) for locally advanced rectal cancer (LARC) has not been evaluated well. We conducted a single‐center, retrospective...
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Oncologic Outcomes of Organ Preserving Approaches in Patients With Rectal Cancer Treated With Preoperative Chemoradiotherapy

Park IJ, Lee JL, Yoon YS, Kim CW, Lim SB, Yu CS, Kim JC

PURPOSE: We evaluated the oncologic outcomes of organ-preserving strategies in patients with rectal cancer treated with preoperative chemoradiotherapy (PCRT). METHODS: Between January 2008 and January 2013, 74 patients who underwent wait-and-watch...
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