Korean J Gynecol Oncol Colposc.  2004 Dec;15(4):325-332.

The Role of Postoperative Adjuvant Chemoradiotherapy for Patients with Invasive Cervical Cancer Discovered after sImple Total Hysterectomy

• Chang SJ
• Lyu MO
• Ryu HS
• Chang KH
• Lee JP

Abstract

OBJECTIVE
: This study was intended to evaluate the efficacy of the adjuvant concurrent chemoradiotherapy in patients with invasive cervical cancer discovered after simple total hysterectomy.
METHODS
: Between September 1994 and May 2004, 20 patients diagnosed with invasive cervical cancer after simple total hysterectomy were treated with radiotherapy alone or with concurrent chemoradiotherapy at the Ajou University Hospital. Concurrent chemoradiotherapy was performed in 16 patients with high risk factors such as positive pelvic lymph nodes, positive surgical margins, parametrial involvement, deep stromal invasion, or lymphovascular space invasion, and radiotherapy alone was administered to 4 patients without high risk factors. A retrospective analysis was conducted to evaluate the treatment outcomes for these 20 patients.
RESULTS
: The mean follow-up period was 26 months (4~53 months). There were no local recurrences and no distant metastases in all patients.
CONCLUSION
: It is suggested that adjuvant concurrent chemoradiotherapy is a useful treatment modality in the patients with invasive cervical cancer discovered after simple total hysterectomy.

Keyword

Adjuvant concurrent chemoradiotherapy; Total hysterectomy; Cervical cancer

MeSH Terms

Chemoradiotherapy
Chemoradiotherapy, Adjuvant*
Follow-Up Studies
Humans
Hysterectomy*
Lymph Nodes
Neoplasm Metastasis
Radiotherapy
Recurrence
Retrospective Studies
Risk Factors
Uterine Cervical Neoplasms*