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The Total Peroxyl Radical-Trapping Capability of Amniotic Fluid in Normal Pregnancy

Kim YH, Ahn BW, Chay KO, Jung YD, Han S, Kim BR, Song TB, Byun JS

  • KMID: 2026734
  • Korean J Obstet Gynecol.
  • 1998 Nov;41(11):2761-2765.
No abstract available.
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Intracellular Aciditfication Induces PC12 cell Apoptosis Through p38 Kinase Activation

Bae WY, Chay KO, lee KY

  • KMID: 2172396
  • Chonnam Med J.
  • 2001 Dec;37(4):335-343.
No abstract available.
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Hemin inhibits lipid peroxidation induced by ascorbate/FeSO4 and 2,2'-azobis-2-amidino-propane hydrochloride (ABAP)

Jung YD, Chay KO, Song DU, Moon JS, Yang SY, Lee MW, Ahn BW

  • KMID: 2052794
  • Exp Mol Med.
  • 1997 Sep;29(3):171-175.
Hemin blocked lipid peroxidations induced by either ascorbate/FeSO4, a metal-catalyzed oxidation system, or 2,2'-azobis-2-amidino-propane hydrochloride (ABAP) which produces peroxy radicals at constant rates. Hemin at very low micromolar concentrations strongly...
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Oxidation of the Sulfhydryl Group by Cephalosporins

Song DU, Chay KO, Jung YD, Kim YJ, Yang SY, Lee MW, Ahn BW

  • KMID: 2172506
  • Chonnam Med J.
  • 1999 Mar;35(1):61-68.
To investigate the mechanism for the adverse reactions of cephalosporins, their ability to oxidize reduced glutathione(GSH) and other sulfhydryl compounds was examined. All the six kinds of cephalosporins used could...
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Purification of a New Antioxidnat Protein from the Hypoxia-Exposed Rat Lung

Jung YD, Chay KO, Song DU, Song H, Yang SY, Lee MW, Ahn BW

  • KMID: 2172519
  • Chonnam Med J.
  • 1998 Jun;34(1):87-95.
Hyperoxia enhances antioxidant potential in rat lung tissues. In this study, an antioxidant protein with Mr of -68 kDa has been purified to nearly homogeneity from the rat lung after...
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Medical Students' Failure Experiences and Their Related Factors

Han ER, Chung EK, Oh SA, Chay KO, Woo YJ

  • KMID: 2306505
  • Korean J Med Educ.
  • 2012 Sep;24(3):233-240.
PURPOSE: A considerable number of medical students drop out due to low academic achievement, and these students have a high probability of repeated failure experiences. This study investigated the personal...
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Detection of Inhibitors of beta-Amyloid Peptide Aggregation in Plant Extracts

Chung MA, Chay KO, Ahn BW

  • KMID: 2172400
  • Chonnam Med J.
  • 2001 Dec;37(4):367-376.
The aggregated beta-amyloid peptides (betaAPs) are suggested to be important in the pathogenesis of Alzheimer's disease. In this study, inhibitory effects of plant extracts on beta-AP aggregation were examined using...
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Xanthine Oxidase Stimulates the Enzyme Inactivation by Metal-Catalyzed Oxidation Systems

Chay KO

  • KMID: 2172399
  • Chonnam Med J.
  • 2001 Dec;37(4):357-365.
A cytosolic protein stimulating the inactivation of glutamine synthetase (GS) by metal-catalyzed oxidation (MCO) systems was purified and characterized from the rat lung. The protein was purified through the following...
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Gastroprotective Effects of Glutinous Rice Extract against Ethanol-, Indomethacin-, and Stress-induced Ulcers in Rats

Song DU, Jang MS, Kim HW, Yoon HJ, Chay KO, Joo YE, Jung YD, Yang SY, Ahn BW

This study was designed to evaluate the efficacy of an orally administered aqueous extract of glutinous rice (GRE) to protect against acute gastric mucosal lesions induced by ethanol, indomethacin, and...
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SB203580, a P38 MAPK Inhibitor, Blocks in vitro Invasion by Human Gastric SNU-638 Cells

Park JC, Yoo HG, Kim HS, Jung MA, Kim MH, Han SW, Chay KO, Shin BA, Ahn BW, Jung YD

  • KMID: 1568911
  • Cancer Res Treat.
  • 2002 Dec;34(6):426-431.
PURPOSE: The role of P38 mitogen-activated protein kinase (MAPK) in gastric cancer invasion has not yet been determined. In this study, we examined the effects of SB203580, a specific P38...
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Nitric Oxide Concentrations in the Uterine, Umbilical, and Peripheral Venous Plasma of Women with Preeclampsia

Park H, Kim YH, Lee JU, Chay KO, Kim HJ, Jeong KP, Kim SM, Song TB, Byun JS

  • KMID: 2262623
  • Korean J Obstet Gynecol.
  • 2002 Feb;45(2):234-238.
OBJECTIVE: The aim of this study was to measure circulating levels of nitric oxide metabolites (nitrites) in the uteroplacental, fetoplacental, and peripheral circulation in women with normal pregnancy and preeclampsia....
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Antioxidant Action of Transthyretin in Human Cerebrospinal Fluid

Yang SY, Chay KO, Park JG, Ryu MH, Hong SN, Kim SH, Ahn BW, Lee JH, Lee MW

  • KMID: 1954697
  • J Korean Neurosurg Soc.
  • 1994 Apr;23(4):375-381.
Protective effect of human cerebrospinal fluid antioxidants against enzyme inactivation caused by metal-catalyzed oxidation systems were investigated. When purified glutamine synthetase(GS) was incubated with human cerebrospinal fluid(CSF), the enzyme was...
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Selenoprotein S Suppression Enhances the Late Stage Differentiation of Proerythrocytes Via SIRT1

Yang HY, Chung KJ, Park HR, Han SJ, Lee SR, Chay KO, Kim IY, Park BJ, Lee TH

  • KMID: 1457118
  • Int J Oral Biol.
  • 2010 Jun;35(2):61-67.
Selenoprotein S (SelS) is widely expressed in diverse tissues where it localizes in the plasma membrane and endoplasmic reticulum. We studied the potential function of SelS in erythrocyte differentiation using...
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Determination of Proper Condition for Detection of Legionella pneumophila by Polymerase Chain Reaction

Jung DW, Lee HC, Chay KO, Chung JK, Ha DR, Ryu PY

  • KMID: 1807455
  • Chonnam Med J.
  • 2000 Jun;36(2):139-147.
BACKGROUND: Legionella pneumophila is the causative agent of Legionnaires' disease, a severe pneumonia, and the nonpneumonic syndrome Pontiac fever. Isolation of L. pneumophila from the patient specimens and environment is...
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NADPH Oxidase Mediates β-Amyloid Peptide-Induced Neuronal Death in Mouse Cortical Cultures

Chay KO, Nam Koong , Hwang S, Kim JK, Bae CS

β-Amyloid peptide (Aβ) is the main component of senile plaques in patients with Alzheimer's disease, and is known to be a main pathogenic factor of the disease. Recent evidence indicates...
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