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Nanoparticle-Based Vaccine Delivery for Cancer Immunotherapy

Park YM, Lee SJ, Kim YS, Lee MH, Cha GS, Jung ID, Kang TH, Han HD

Development of nano-sized carriers including nanoparticles, nanoemulsions or liposomes holds great potential for advanced delivery systems for cancer immunotherapy, as such nanostructures can be used to more effectively manipulate or...
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Porphyromonas gingivalis accelerates atherosclerosis through oxidation of high-density lipoprotein

Kim HJ, Cha GS, Kim HJ, Kwon EY, Lee JY, Choi J, Joo JY

PURPOSE: The aim of this study was to evaluate the ability of Porphyromonas gingivalis (P. gingivalis) to induce oxidation of high-density lipoprotein (HDL) and to determine whether the oxidized HDL...
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Atheroprotective nasal immunization with a heat shock protein 60 peptide from Porphyromonas gingivalis

Joo JY, Cha GS, Kim HJ, Lee JY, Choi J

Purpose: Immunization with Porphyromonas gingivalis heat shock protein 60 (PgHSP60) may have an immunoregulatory effect on atherogenesis. The aim of this study was to determine whether nasal immunization with a...
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Robust immunoreactivity of teenager sera against peptide 19 from Porphyromonas gingivalis HSP60

Kwon EY, Cha GS, Joo JY, Lee JY, Choi J

PURPOSE: Epitope spreading is a phenomenon in which distinct subdominant epitopes become major targets of the immune response. Heat shock protein (HSP) 60 from Porphyromonas gingivalis (PgHSP60) and peptide 19...
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Adaptation of Isolation Guidelines for Health Care Settings

Ryu JG, Jeong JS, Jeong IS, Kim JH, Hong EY, Kim HS, Jung YS, Kwon JS, Lee JY, Choi JY, Kim KS, Kim EH, Cha GS, Kim EJ, Park KH, Seo HJ

PURPOSE: This purpose of this study was to develop evidence-based practice guideline for isolation in health care settings to prevent transmission of infectious diseases utilizing guideline adaption process. METHODS: The process...
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Electrophysiologic Factors Responsible for the Induction of AV Nodal Reentrant Tachycardia

Cho JG, Shin SC, Rhew JY, Bae Y, Kim JW, Kim SH, Kim JH, Seo JP, Cha GS, Park JC, Jeong MH, Park JC, Kang JC

  • KMID: 2080529
  • Korean J Med.
  • 1997 Jun;52(6):786-796.
OBJECTIVES: Although a subtle balance between conduction time of the antgrade slow pathway and refractory period of the retrograde fast pathway is known to play the most critical role in...
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Targeting the epitope spreader Pep19 by naïve human CD45RA⁺ regulatory T cells dictates a distinct suppressive T cell fate in a novel form of immunotherapy

Kim HJ, Cha GS, Joo JY, Lee J, Kim SJ, Lee J, Park SY, Choi J

PURPOSE: Beyond the limited scope of non-specific polyclonal regulatory T cell (Treg)-based immunotherapy, which depends largely on serendipity, the present study explored a target Treg subset appropriate for the delivery...
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Electrophysiologic Characteristics and Catheter Ablation of Idiopathic Left Ventricular Tachycardia

Seo JP, Kim KH, Kim W, Kim JW, Kim SH, Kim JH, Cha GS, Park JC, Park JH, Jeong MH, Cho JG, Park JC, Kang JC

BACKGROUND: Idiopathic left ventricular tachycardia (ILVT), one of common idiopathic ventricular tachycardias which develop without structural abnormality of the heart. It has been reported that ILVT has a typical QRS...
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Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells

Park SN, Noh KT, Jeong YI, Jung ID, Kang HK, Cha GS, Lee SJ, Seo JK, Kang DH, Hwang TH, Lee EK, Kwon B, Park YM

  • KMID: 2154227
  • Exp Mol Med.
  • 2013 Feb;45(2):e8.
We evaluated the effectiveness of rhamnogalacturonan II (RG-II)-stimulated bone marrow-derived dendritic cells (BMDCs) vaccination on the induction of antitumor immunity in a mouse lymphoma model using EG7-lymphoma cells expressing ovalbumin...
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