- Ceramides and Cell Signaling Molecules in Psoriatic Epidermis: Reduced Levels of Ceramides, PKC-alpha, and JNK
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Lew BL, Cho Y, Kim J, Sim WY, Kim NI
- KMID: 2157790
- J Korean Med Sci.
- 2006 Feb;21(1):95-99.
- doi: 10.3346/jkms.2006.21.1.95
Ceramides are the main lipids in the stratum corneum and are generated during cellular stress and apoptosis by de novo synthesis or by the action of sphingomyelinase. In addition, they... -
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- An Inverse Relationship Between Ceramide Synthesis and Clinical Severity in Patients with Psoriasis
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Cho Y, Lew BL, Seong K, Kim NI
- KMID: 1778569
- J Korean Med Sci.
- 2004 Dec;19(6):859-863.
- doi: 10.3346/jkms.2004.19.6.859
Ceramides play major roles in maintaining the epidermal barrier. It has been sus-pected that the depletion of ceramides, associated with disrupted barrier function in the epidermis, leads to the clinical... -
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