- The Effects of Antioxidants and Nitric Oxide Modulators on Hepatic Ischemic-Reperfusion Injury in Rats
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Rhee JE, Jung SE, Shin SD, Suh GJ, Noh DY, Youn YK, Oh SK, Choe KJ
- KMID: 1109759
- J Korean Med Sci.
- 2002 Aug;17(4):502-506.
- doi: 10.3346/jkms.2002.17.4.502
Ischemic-reperfusion injury (IRI) is thought to be caused by oxygen radicals. Nitric oxide (NO) also has been thought to play a key role in IRI. This experiment was designed to... -
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- Ischemic preconditioning in the rat hippocampus increases antioxidant activities but does not affect the level of hydroxyl radicals during subsequent severe ischemia
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Choi YS, Cho KO, Kim EJ, Sung KW, Kim SY
- KMID: 756079
- Exp Mol Med.
- 2007 Aug;39(4):556-563.
Several studies have demonstrated that ischemic preconditioning increases superoxide dismutase activity, but it is unclear how ischemic preconditioning affects events downstream of hydrogen peroxide production during subsequent severe ischemia and... -
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- Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes
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Kim YH, Shin MJ
- KMID: 1081461
- Exp Mol Med.
- 2002 May;34(2):123-130.
Membrane-associated cytotoxicity induced by hydrophobic bile salts is a major contributing factor leading to liver diseases. Administration of ursodeoxycholate reduces serum liver enzymes in chronic liver diseases but the nature... -
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- Effects of N-acetyl-L-cysteine and Glutathione on Antioxidant Status of Human Serum and 3T3 Fibroblasts
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Hong SY, Yang JO, Lee EY, Lee ZW
- KMID: 1130033
- J Korean Med Sci.
- 2003 Oct;18(5):649-654.
- doi: 10.3346/jkms.2003.18.5.649
The effectiveness of several sulfhydryl compounds in the treatment of paraquat intoxication has been previously tested based on their antioxidant ability. However, practical guidelines for their clinical use remain to... -
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- Antioxidant activity of extracts from Euryale ferox seed
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Lee SE, Ju EM, Kim JH
- KMID: 1081458
- Exp Mol Med.
- 2002 May;34(2):100-106.
Euryale ferox has been widely used in traditional oriental medicine to treat a variety of illness. However, very little is known about the cellular actions by which this plant mediates... -
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- Alterations in antioxidant function and cell apoptosis in duck spleen exposed to molybdenum and/or cadmium
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Zhang M, Luo J, Zhang C, Cao H, Xia B, Hu G
- KMID: 2412572
- J Vet Sci.
- 2017 Jun;18(2):193-200.
- doi: 10.4142/jvs.2017.18.2.193
To investigate the effects of molybdenum (Mo) and/or cadmium (Cd) on antioxidant function and the apoptosis-related genes in duck spleens. Sixty healthy 11-day-old ducks were randomly divided into six groups... -
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- Generation of Nitric Oxide in the Opossum Lower Esophageal Sphincter during Physiological Experimentation
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Lee SJ, Park H, Chang JH, Conklin JL
- KMID: 1110746
- Yonsei Med J.
- 2006 Apr;47(2):223-229.
- doi: 10.3349/ymj.2006.47.2.223
Lipopolysaccharide (LPS), given in vivo, modulates opossum esophageal motor functions by inducing the inducible nitric oxide synthase (iNOS), which increases nitric oxide (NO) production. Superoxide, a NO scavenger, is generated... -
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- The dose of cyclophosphamide for treating paraquat-induced rat lung injury
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Choi JS, Jou SS, Oh MH, Kim YH, Park MJ, Gil HW, Song HY, Hong SY
- KMID: 1503779
- Korean J Intern Med.
- 2013 Jul;28(4):420-427.
- doi: 10.3904/kjim.2013.28.4.420
BACKGROUND/AIMS: Cyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. METHODS: Adult male Sprague-Dawley rats... -
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- Repeated dose toxicity of alfa-cypermethrin in rats
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Manna S, Bhattacharyya D, Mandal TK, Das S
- KMID: 1099838
- J Vet Sci.
- 2004 Sep;5(3):241-245.
The present study was performed to investigate the subacute effect of alpha-cypermethrin (alpha-CP) in rats. Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated... -
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- Antidiabetic Effects of Corni Fructus Extract in Streptozotocin-Induced Diabetic Rats
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Gao D, Li Q, Gao Z, Wang L
- KMID: 1716865
- Yonsei Med J.
- 2012 Jul;53(4):691-700.
- doi: 10.3349/ymj.2012.53.4.691
PURPOSE: Diabetes is the leading cause of end-stage renal failure. The present study was undertaken to characterize the effects of Corni Fructus on diabetic nephropathy in streptozotocin-induced diabetic rats and... -
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- A Case of Bacteremia by Neisseria gonorrhoeae Coincident with Massive Hemorrhage of Esophageal Varices
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Won D, An D, Kim MN, Lee YS
- KMID: 1094352
- Korean J Lab Med.
- 2011 Apr;31(2):118-121.
- doi: 10.3343/kjlm.2011.31.2.118
A 42-yr-old man with hepatitis B virus associated liver cirrhosis was admitted to the emergency room because of multiple seizures, a history of chills and myalgia over the previous 2... -
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- Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver
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Kweon S, Kim Y, Choi H
- KMID: 1093609
- Exp Mol Med.
- 2003 Oct;35(5):371-378.
This study was conducted to examine the effects of dietary grape extracts on preneoplastic foci formation in rat hepatocarcinogenesis, and related hepatic enzymes. Male Sprague-Dawley rats were fed basal diet... -
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- Natural compounds, fraxin and chemicals structurally related to fraxin protect cells from oxidative stress
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Whang WK, Park HS, Ham I, Oh M, Namkoong H, Kim HK, Hwang DW, Hur SY, Kim TE, Park YG, Kim JR, Kim JW
- KMID: 1089453
- Exp Mol Med.
- 2005 Oct;37(5):436-446.
Coumarins comprise a group of natural phenolic compounds found in a variety of plant sources. In view of the established low toxicity, relative cheapness, presence in the diet and occurrence... -
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