- Activation of Caspase-3 in Hydrogen Peroxide-Induced Apoptosis of Human Leukemia HL 60 Cells
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Jeon S, Woo CW, Lee J, Sohn J, Lee KC, Son C, Lee J
- KMID: 2278318
- Korean J Pediatr Hematol Oncol.
- 2004 Oct;11(2):228-235.
PURPOSE: Reactive oxygen species have been recognized as a common signaling mediator in diverse stimuli-induced apoptosis and hydrogen peroxide is a natural one of those reactive oxygen species. This study... -
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- The Apoptosis Induced by Ceramide in the Endothelial Cell
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Lee SY, Kim TI, Tchag H
- KMID: 2206691
- J Korean Ophthalmol Soc.
- 2003 Sep;44(9):2128-2136.
PURPOSE: To evaluate the effect of variable ceramides on the apoptosis of corneal endothelial cell and then, if ceramide induce the apoptosis in endothelial cells, via which pathway apoptosis occur.... -
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- Effects of Recombinant EPO on Death of Cortical Neuron in Chronic Hypoxia
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Kim HJ, Baek JG, Yang JS, Kang KY, Kim KR, Kim H
- KMID: 1598729
- Korean J Phys Anthropol.
- 2005 Dec;18(4):291-301.
Chronic hypoxia has been associated with change in neurovascular behavior, mediated, in part, by erythropoietin (EPO). EPO, a hematopoietic growth factor, could act as a neurotrophic factor. In the present... -
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- The Ability of Cyclosporine (CsA) to Induce Oxigen Free Radicals in a Rat Osteoblast Cell Line
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Jung MH, Lee TH, Oh YL, Lee JY, Yang SO, Choi WH, Kim HY
- KMID: 2321565
- J Korean Soc Osteoporos.
- 2010 Aug;8(2):171-177.
OBJECTIVES: This study examined the ability of Cyclosporine (CsA) to induce apoptosis in a rat osteoblast cell line. METHODS: Rat osteoblast ROS 17/2.8 cells were cultured, and treated with with 0.1~40... -
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- alpha-Tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells
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Lim SJ, Choi MK, Kim MJ, Kim JK
- KMID: 1009395
- Exp Mol Med.
- 2009 Oct;41(10):737-745.
- doi: 10.3858/emm.2009.41.10.080
Paclitaxel is one of the chemotheraputic drugs widely used for the treatment of nonsmall cell lung cancer (NSCLC) patients. Here, we tested the ability of alpha-tocopheryl succinate (TOS), another promising... -
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- Induction of apoptosis by a hexane extract of aged black garlic in the human leukemic U937 cells
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Park C, Park S, Chung YH, Kim GY, Choi YW, Kim BW, Choi YH
- KMID: 2313720
- Nutr Res Pract.
- 2014 Apr;8(2):132-137.
BACKGROUND/OBJECTIVES: In this study, the apoptogenic activity and mechanisms of cell death induced by hexane extract of aged black garlic (HEABG) were investigated in human leukemic U937 cells. MATERIALS/METHODS: Cytotoxicity was... -
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- Inhibition of PKC Epsilon Attenuates Cigarette Smoke Extract-Induced Apoptosis in Human Lung Fibroblasts (MRC-5 Cells)
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Kang SM, Yoon JY, Kim YJ, Lee SP, Jeong SH, Park JW
- KMID: 1846415
- Tuberc Respir Dis.
- 2011 Aug;71(2):88-96.
- doi: 10.4046/trd.2011.71.2.88
BACKGROUND: It is known that cigarette smoke (CS) causes cell death. Apoptotic cell death is involved in the pathogenesis of CS-related lung diseases. Some members of the protein kinase C... -
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- Pro-Apoptotic Activity of 4-Isopropyl-2-(1-Phenylethyl) Aniline Isolated from Cordyceps bassiana
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Kim MS, Lee Y, Sung GH, Kim JH, Park JG, Kim HG, Baek KS, Cho JH, Han J, Lee KH, Hong S, Kim JH, Cho JY
- KMID: 2382367
- Biomol Ther.
- 2015 Jul;23(4):367-373.
- doi: 10.4062/biomolther.2015.021
Cordyceps species including Cordyceps bassiana are a notable anti-cancer dietary supplement. Previously, we identified several compounds with anti-cancer activity from the butanol fraction (Cb-BF) of Cordyceps bassiana. To expand the... -
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- beta-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway
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Yu HY, Kim SO, Jin CY, Kim GY, Kim WJ, Yoo YH, Choi YH
- KMID: 2170635
- Biomol Ther.
- 2014 May;22(3):184-192.
beta-lapachone is a naturally occurring quinone that selectively induces apoptotic cell death in a variety of human cancer cells in vitro and in vivo; however, its mechanism of action needs... -
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- Anti-carcinogenic actions of glycoprotein conjugated with isoflavones from submerged-liquid culture of Agaricus blazei mycelia through reciprocal expression of Bcl-2 and Bax proteins
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Kim YS, Kim BH, Kim GS, Jang JS, Kim SY, Choi BD, Kim JO, Ha YL
- KMID: 2169000
- J Biomed Res.
- 2014 Dec;15(4):200-206.
- doi: 10.12729/jbr.2014.15.4.200
Glycoproteins isolated from fruit bodies and mycelial cultures of mushrooms exhibit anti-carcinogenic actions in human cancer cells and animal tumor cells by induction of apoptosis. Here, we report that isoflavone-conjugated... -
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- Involvement of Bcl-2 Family and Caspases Cascade in Sodium Fluoride-Induced Apoptosis of Human Gingival Fibroblasts
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Jung JY, Park JH, Jeong YJ, Yang KH, Choi NK, Kim SH, Kim WJ
- KMID: 2071638
- Korean J Physiol Pharmacol.
- 2006 Oct;10(5):289-295.
Sodium fluoride (NaF) has been shown to be cytotoxic and elicit inflammatory response in human. However, the cellular mechanisms underlying NaF-induced cytotoxicity in periodontal tissues have not yet been elucidated.... -
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- Sensitization of TNF alpha and Agonistic FAS/CD95 Antibody-Induced Apoptosis by INF gamma on Neuroblastoma Cells
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Bang HI, Kim JD, Choi DY
- KMID: 2335746
- J Korean Pediatr Soc.
- 2003 Jul;46(7):702-709.
PURPOSE: IFN gamma sentitizes many tumor cells to TNF alpha and FASL-mediated apoptosis by enhancing the expression of TNF or FAS/CD95 receptor and modulating the activation of caspase and Bcl-2... -
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