- Risk assessment of di(2-ethylhexyl) phthalate in the workplace
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Kim HY
- KMID: 2469667
- Environ Health Toxicol.
- 2016 ;31(1):e2016011.
- doi: 10.5620/eht.e2016011
OBJECTIVES: A hazard assessment of di(2-ethylhexyl) phthalate (DEHP), a commonly used workplace chemical, was conducted in order to protect the occupational health of workers. A literature review, consisting of both... -
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- An Experimental Study on the Chemopreventive effect of Chlorophyllin in Hamster Cheek Pouch Tumor induced by 7, 12-dimethylbenz[a]anthracene
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Yoon KH
- KMID: 1961290
- J Korean Assoc Oral Maxillofac Surg.
- 2000 Apr;26(2):137-145.
Carcinogenesis is a multi-stage process that generally consists of at least three steps; initiation, promotion, and progression. If one of these carcinogenic steps were suppressed or delayed, the cancer could... -
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- Guideline on safety evaluation of cell-based medicinal products for animal use
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Ku HO, Yi H, Park YI, Jeon BS, Kang HG, Kim YS, Park BK
- KMID: 2454016
- J Vet Sci.
- 2019 Mar;20(2):e14.
- doi: 10.4142/jvs.2019.20.e14
With the increased use of cell therapy in the veterinary sector, there is a growing demand for the development of cell-based medicinal products and the determination of their safety. Currently,... -
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- Preclinical evaluation of prototype products
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Park JC, Lee DH, Suh H
- KMID: 1726192
- Yonsei Med J.
- 1999 Dec;40(6):530-535.
- doi: 10.3349/ymj.1999.40.6.530
Preclinical evaluation of medical devices (prototype products) offers the opportunity to investigate and study the intended use of device materials. Preclinical evaluation programs are designed to determine the... -
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- Inhibition by Ginseng of Colon Carcinogenesis in Rats
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Fukushima , Wanibuchi , Li W
- KMID: 1721179
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S75-S80.
- doi: 10.3346/jkms.2001.16.S.S75
The inhibitory effects of ginseng on the development of 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in the colon were investigated in rats. Male, 6-week-old rats were injected with DMH once... -
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- In vitro Culture of Hepatitis C Virus (HCV) Using Immortalized Hepatocyte
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Choi JE, Hur W, Shin JY, Piao LS, Yoon SK
- KMID: 1767619
- Korean J Gastroenterol.
- 2008 Sep;52(3):150-160.
BACKGROUND/AIMS: It is essential to develop an in vitro culture model of primary hepatocytes for the study of hepatocellular function and the pathogenesis of hepatitis C virus (HCV) infection. In... -
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- RPS15a Silencing Suppresses Cell Proliferation and Migration of Gastric Cancer
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Shi D, Liu J
- KMID: 2426330
- Yonsei Med J.
- 2018 Dec;59(10):1166-1173.
- doi: 10.3349/ymj.2018.59.10.1166
PURPOSE: Information on the possible role of the ribosomal protein S15a (RPS15a) in gastric cancer is scarce. The aim of this study was to evaluate the impact of RPS15a gene... -
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- An alternatively spliced form of Met receptor is tumorigenic
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Lee JH, Gao CF, Lee CC, Kim MD, Vande Woude GF
- KMID: 1098091
- Exp Mol Med.
- 2006 Oct;38(5):565-573.
The Met tyrosine kinase receptor is a widely expressed molecule, which mediates pleiotropic cellular responses following activation by its ligand, hepatocyte growth factor/scatter factor (HGF/SF). Previously, one of the authors... -
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- Safety Evaluation of Human Fibroblasts in Mice: Tumorigenicity, 13-week Toxicity and Distribution Studies
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Choi HJ, Kwon E, Sohn JH, Che JH, Lee KH, Kim JW, Choi J, Kang BC
- KMID: 2312064
- Lab Anim Res.
- 2010 Jun;26(2):181-196.
- doi: 10.5625/lar.2010.26.2.181
Human fibroblasts were developed for cellular therapy with the aim of correcting of depressed scars, but the safety of that in vivo is unclear. In this study, we assessed the... -
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