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Calcium cycling proteins in heartfailure, cardiomyopathy and arrhythmias

Minamisawa S, Sato Y, Cho MC

  • KMID: 1097100
  • Exp Mol Med.
  • 2004 Jun;36(3):193-203.
A growing body of evidence, including studies using genetically engineered mouse models, has shown that Ca2+ cycling and Ca2+ -dependent signaling pathways play a pivotal role in cardiac hypertrophy and...
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High Dose Vitamin D3 Attenuates the Hypocalciuric Effect of Thiazide in Hypercalciuric Rats

Jang HR, Lee JW, Kim S, Heo NJ, Lee JH, Kim HS, Jung JY, Oh YK, Na KY, Han JS, Joo KW

Thiazide is known to decrease urinary calcium excretion. We hypothesized that thiazide shows different hypocalciuric effects depending on the stimuli causing hypercalciuria. The hypocalciuric effect of hydrochlorothiazide (HCTZ) and the...
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Spinocerebellar Ataxia Type 6 and Episodic Ataxia Type 2 in a Korean Family

Koh SH, Kim HT, Kim SH, Lee GY, Kim J, Kim MH

Spinocerebellar ataxia type 6 (SCA6), episodic ataxia type 2 (EA2) and familial hemiplegic migraine (FHM) have been known as allelic disorders, which are caused by the alteration of the alpha1A...
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Whole-Genome Analysis in Korean Patients with Autoimmune Myasthenia Gravis

Na SJ, Lee JH, Kim SW, Kim DS, Shon EH, Park HJ, Shin HY, Kim SM, Choi YC

PURPOSE: The underlying cause of myasthenia gravis (MG) is unknown, although it likely involves a genetic component. However, no common genetic variants have been unequivocally linked to autoimmune MG. We...
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Long QT Syndrome: a Korean Single Center Study

Lee YS, Kwon BS, Kim GB, Oh SI, Bae EJ, Park SS, Noh CI

The long QT syndrome (LQTS) is a rare hereditary disorder in which affected individuals have a possibility of ventricular tachyarrhythmia and sudden cardiac death. We investigated 62 LQTS (QTc >...
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Genomic structure of the regulatory region of the voltage-gated calcium channel alpha 1D

Kim HL, Chang YJ, Lee SM, Hong YS

  • KMID: 755016
  • Exp Mol Med.
  • 1998 Dec;30(4):246-251.
In excitable and endocrine organs, calcium influxes through the L-type voltage-gated calcium channel (VGCC) which is composed of four (alpha 1, alpha 2, beta, and gamma) subunits. Temporal and spatial...
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Protective Effects of Gabapentin on Allodynia and alpha2delta1-Subunit of Voltage-dependent Calcium Channel in Spinal Nerve-Ligated Rats

Hahm TS, Ahn HJ, Bae CD, Kim HS, Lim SW, Cho HS, Lee SM, Sim WS, Kim JA, Gwak MS, Choi SJ

This study was designed to determine whether early gabapentin treatment has a protective analgesic effect on neuropathic pain and compared its effect to the late treatment in a rat neuropathic...
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