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Impact of calcineurin inhibitors on rat glioma cells viability

Seong JH, Park WY, Paek JH, Park SB, Han S, Mun KC, Jin K

BACKGROUND: Although kidney transplantation outcomes have improved dramatically after using calcineurin inhibitors (CNIs), CNI toxicity continues to be reported and the mechanism remains uncertain. Here, we investigated the neurotoxicity of...
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Progression of diabetic nephropathy after successful pancreas transplantation alone: a case report

Kim Y, Kim DI, Shim JR, Lee TB, Yang KH, Ryu JH, Lee HJ, Choi BH

Pancreas transplantation is the only method that can nearly cure insulin-dependent diabetes mellitus. However, the effect of pancreas transplantation on patients with diabetic nephropathy has recently been considered controversial. In...
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Pimecrolimus increases the melanogenesis and migration of melanocytes in vitro

Xu P, Chen J, Tan C, Lai RS, Min ZS

Vitiligo is an intriguing depigmentary disorder and is notoriously difficult to be treated. The ultimate goal of vitiligo treatment is to replenish the lost melanocytes by immigration from hair follicle...
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A Case of Refractory Vitiligo That Was Treated with a Combination of Non-ablative 1550-nm Erbium:Glass Fractional Laser, Narrow-band UVB, and a Topical Agent

Park JB, Park JH, Chun SH, Jang HW, Ryu HJ, Kim IH

  • KMID: 2251147
  • Korean J Dermatol.
  • 2016 May;54(4):280-283.
There are many therapeutic methods for treating vitiligo, including narrow-band UVB, topical corticosteroids, calcineurin inhibitors, excimer laser, and surgical methods, such as autologous epidermal grafting and dermabrasion. However, although various...
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Allergic conjunctivitis in Asia

Thong BY

Allergic conjunctivitis (AC), which may be acute or chronic, is associated with rhinitis in 30%–70% of affected individuals, hence the term allergic rhinoconjunctivitis (AR/C). Seasonal and perennial AC is generally...
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Sirolimus Conversion Efficacy for Graft Function Improvement and Histopathology in Renal Recipients with Mild to Moderate Renal Insufficiency

Joo DJ, Yang CW, Jeong HJ, Lim BJ, Huh KH, Chung BH, Choi YJ, Kang SW, Kim YS

This study was designed to evaluate whether sirolimus (SRL) conversion effectively improves renal function and histopathology in calcineurin inhibitor (CNI)-treated renal recipients with mild to moderate renal insufficiency. SRL conversion...
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Treatment of Atopic Dermatitis

Han TY, Na CH, Lee JH, Kim HO, Park CO, Seo YJ, Son SW, Shin MK, Ahn JY, Lee YW, Jang YH, Park YL, Lew BL

  • KMID: 2437050
  • Korean J Dermatol.
  • 2018 Dec;56(10):581-593.
Atopic dermatitis (AD) is a common, chronic, relapsing, inflammatory skin disease that affects both children and adults. AD is the cause of considerable morbidity including severe pruritus and impaired quality...
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Efficacy and Utility of Wet Wrap Dressing for Patients with Pediatric Atopic Dermatitis

Choi JW, Loh SH, Lew BL, Sim WY

  • KMID: 2454369
  • Korean J Dermatol.
  • 2019 Jul;57(6):301-306.
BACKGROUND: Management of atopic dermatitis (AD) involves the regular use of emollients together with topical steroids or calcineurin inhibitors for acute flares. However, the long-term use of oral medications in...
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A clinician's reference guide for the management of atopic dermatitis in Asians

Chow S, Seow CS, Dizon MV, Godse K, Foong H, Chan V, Khang TH, Xiang L, Hidayat S, Listiawan , Triwahyudi D, Gondokaryono SP, Sutedja E, Diana IA, Suwarsa O, Dharmadji , Siswati AS, Danarti R, Soebaryo R, Budianti W, for the Asian Academy of Dermatology & Venereology

BACKGROUND: Atopic dermatitis (AD) is a common skin condition among Asians. Recent studies have shown that Asian AD has a unique clinical and immunologic phenotype compared with European/American AD. OBJECTIVE: The...
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