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Cerulein Pancreatitis: Oxidative Stress, Inflammation, and Apoptosis

Kim H

  • KMID: 2135123
  • Gut Liver.
  • 2008 Sep;2(2):74-80.
Cerulein pancreatitis is similar to human edematous pancreatitis, manifesting with dysregulation of digestive enzyme production and cytoplasmic vacuolization, the death of acinar cells, edema formation, and infiltration of inflammatory cells...
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Effects of Pancreatic Polypeptide on the Secretion of Enzymes and Electrolytes by in Vitro Preparations of Rat and Cat Pancreas

Kim KH, Case RM

Pancreatic polypeptie (PP) is released from the pancreas in response to vagal stimulation. Amongst other effects, PP has been reported to inhibit pancreatic exocrine function. Apart from any potential physiological...
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Role of Janus Kinase/Signal Transducers and Activators of Transcription in the Pathogenesis of Pancreatitis and Pancreatic Cancer

Yu JH, Kim H

  • KMID: 2167409
  • Gut Liver.
  • 2012 Oct;6(4):417-422.
In the pathogenesis of pancreatitis, oxidative stress is involved in the activation of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway and cytokine expression. High serum levels of...
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Altered Gene Expression in Cerulein-Stimulated Pancreatic Acinar Cells: Pathologic Mechanism of Acute Pancreatitis

Yu JH, Lim JW, Kim H

Acute pancreatitis is a multifactorial disease associated with the premature activation of digestive enzymes. The genes expressed in pancreatic acinar cells determine the severity of the disease. The present study...
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Membrane Proteome Analysis of Cerulein-Stimulated Pancreatic Acinar Cells: Implication for Early Event of Acute Pancreatitis

Lee J, Seo JH, Lim JW, Kim H

  • KMID: 2167210
  • Gut Liver.
  • 2010 Mar;4(1):84-93.
BACKGROUND/AIMS: Cerulein pancreatitis is similar to human edematous pancreatitis with dysregulation of the production and secretion of digestive enzymes, edema formation, cytoplasmic vacuolization and the death of acinar cells. We...
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The Role of Nitric Oxide in Experimental Cerulein Induced Pancreatitis

Um SH, Kwon YD, Kim CD, Lee HS, Jeen YT, Chun HJ, Lee SW, Choi JH, Ryu HS, Hyun JH

An enhanced formation of nitric oxide(NO), due to the induction of inducible nitric oxide synthase(iNOS), has been implicated in the pathogenesis of shock and inflammation, but its role in acute...
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Heat Shock Proteins and Autophagy in Rats with Cerulein-Induced Acute Pancreatitis

Kim JN, Lee HS, Ryu SH, Kim YS, Moon JS, Kim CD, Chang IY, Yoon SP

  • KMID: 2284244
  • Gut Liver.
  • 2011 Dec;5(4):513-520.
BACKGROUND/AIMS: Heat shock proteins (HSPs) protect rats from cerulein-induced acute pancreatitis (AP) by preventing the subcellular redistribution of cathepsin B and the activation of trypsinogen. Autophagy plays a critical role...
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