- Presymptomatic Identification of CDH1 Germline Mutation in a Healthy Korean Individual with Family History of Gastric Cancer
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Choi HJ, Ki CS, Suh SP, Kim JW
- KMID: 1791955
- Ann Lab Med.
- 2014 Sep;34(5):386-389.
- doi: 10.3343/alm.2014.34.5.386
Gastric cancer (GC) is one of the most common cancers with high morbidity and mortality. Familial GC is seen in 10% of cases, and approximately 3% of familial GC cases... -
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- Association between CDH13 Variants and Cardiometabolic and Vascular Phenotypes in a Korean Population
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Lee JH, Shin DJ, Park S, Kang SM, Jang Y, Lee SH
- KMID: 1798124
- Yonsei Med J.
- 2013 Nov;54(6):1305-1312.
- doi: 10.3349/ymj.2013.54.6.1305
PURPOSE: Although some CDH13 single nucleotide polymorphisms (SNPs) have been shown to be determinants of blood adiponectin levels, the clinical implications of CDH13 variants are not yet completely understood. The... -
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- Promoter Methylation of E-cadherin in Hepatocellular Carcinomas and Dysplastic Nodules
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Kwon GY, Yoo BC, Koh KC, Cho JW, Park WS, Park CK
- KMID: 1095198
- J Korean Med Sci.
- 2005 Apr;20(2):242-247.
- doi: 10.3346/jkms.2005.20.2.242
In order to clarify the significance of E-cadherin methylation in multistep hepatocarcinogenesis, we examined the methylation status of the E-cadherin promoter region, using methylation-specific polymerase chain reaction in 64 hepatocellular... -
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- Identification of DNA methylation associated gene signatures in endometrial cancer via integrated analysis of DNA methylation and gene expression systematically
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Men C, Chai H, Song X, Li Y, Du H, Ren Q
- KMID: 2413209
- J Gynecol Oncol.
- 2017 Nov;28(6):e83.
- doi: 10.3802/jgo.2017.28.e83
OBJECTIVE: Endometrial cancer (EC) is a common gynecologic cancer worldwide. However, the pathogenesis of EC has not been epigenetically elucidated. Here, this study aims to describe the DNA methylation profile... -
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- A Single Nucleotide Polymorphism in the E-cadherin Gene Promoter-160 is Not Associated with Risk of Korean Gastric Cancer
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Park WS, Cho YG, Park JY, Kim CJ, Lee JH, Kim HS, Lee JW, Song YH, Park CH, Park YK, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY
- KMID: 648900
- J Korean Med Sci.
- 2003 Aug;18(4):501-504.
- doi: 10.3346/jkms.2003.18.4.501
Recently, the -160 C/A polymorphism, located within the regulatory region of E-cadherin promoter, has been shown to influence E-cadherin transcription by altering transcription factor binding. We examined the effect of... -
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- FAT1 Gene Alteration in Facioscapulohumeral Muscular Dystrophy Type 1
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Park HJ, Lee W, Kim SH, Lee JH, Shin HY, Kim SM, Park KD, Lee JH, Choi YC
- KMID: 2418800
- Yonsei Med J.
- 2018 Mar;59(2):337-340.
- doi: 10.3349/ymj.2018.59.2.337
Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is caused by contraction of the D4Z4 repeat array. Recent studies revealed that the FAT1 expression is associated with disease activity of FSHD, and... -
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- Expression of E-cadherin in pig kidney
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Lee SY, Han SM, Kim JE, Chung KY, Han KH
- KMID: 1712303
- J Vet Sci.
- 2013 Dec;14(4):381-386.
- doi: 10.4142/jvs.2013.14.4.381
E-cadherin is a cell adhesion molecule that plays an important role in maintaining renal epithelial polarity and integrity. The purpose of this study was to determine the exact cellular localization... -
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- Triptolide inhibits ovarian cancer cell invasion by repression of matrix metalloproteinase 7 and 19 and upregulation of E-cadherin
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Zhao H, Yang Z, Wang X, Zhang X, Wang M, Wang Y, Mei Q, Wang Z
- KMID: 1401755
- Exp Mol Med.
- 2012 Nov;44(11):633-641.
Triptolide, a compound extracted from the traditional Chinese medicine preparation of Tripterygium wilfordii Hook F., has been reported to have anti-inflammatory and anti-cancer activities. However, its effect on ovarian cancer... -
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