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Increased UDP-Glucuronosyltransferase Activity in the Liver Butylated Hydroxyanisole and Butylated Hydroxytoluence-Treated Rats

Hong YS

Butylated hydroxyanisole(BHA) has been shown to decrease the toxicological and carcinogenic potential of a variety of chemicals. One possible mechanism for chemoprotection is that BHA increases intestinal UDP-glucronosyltransferase activity and...
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The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue

Sung NE

To evaluate the effect of BHA and BHT on liver tissue, BHA and BHT, 100mg and 200mg/kg B.W. respectively, were given to experimental animals for 4 months. Microsomal cytochrome P-450, cytochrome...
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Enhancement of O-dealkylation in Mouse Liver by Dietary Administrations of BHA and BHT: Studies with Isolated Perfused Livers and Hepatic Microsomes

Ji SC, Conway JG, Thurman RG, Cha YN

Effects of feeding 2(3)-tert-butyl 4-hydroxyanisole (BHA) and 3, 5-di-tert-butyl 4-hydroxytoluene (BHT) on the rates of mixed function oxidation and conjugation enzyme reactions have been determined using isolated hepatic microsomal fractions...
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Effect of t-butylhydroperoxide on Na+/-dependent glutamate uptake in rabbit brain synaptosome

Lee HJ, Kim YK

  • KMID: 2071508
  • Korean J Physiol Pharmacol.
  • 1997 Aug;1(4):367-376.
The effect of an organic peroxide, t-butylhydroperoxide (t-BHP), on glutamate uptake was studied in synaptosomes prepared from cerebral cortex. t-BHP inhibited the Na+/-dependent glutamate uptake with no change in the Na+/-independent uptake. This...
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Enhancements of Mouse Hepatic Cytosol Enzyme Activities Involved in UDP-Glucuronic Acid Synthesis, Glutathione Reduction and Conjugation with Butylated Hydroxyanisole (BHA) and Its Structural Analogs

Cha YN, Chung JH, Heine HS, Hong SS

Activities of hepatic cytosol enzymes involved in UDP-g1ucuronic acid synthesis as well as in glutathione reduction and conjugation systems were determined following administrations of butylated hydroxyanisole (approximately 5 mmol/kg body...
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Antioxidative and aldose reductase-inhibitory effects of a fermentation filtrate of Rubus coreanus

Kwon SC, Kim YB

Antioxidative and aldose reductase (AR)-inhibitory effects of a fermentation filtrate of Rubus coreanus (FRC) were investigated using corneal/retinal homogenate and lens cytosol, respectively. Rat corneal/retinal homogenate was treated with 50...
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Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes

Hwang GH, Jeon YJ, Han HJ, Park SH, Baek KM, Chang W, Kim JS, Kim LK, Lee YM, Lee S, Bae JS, Jee JG, Lee MY

Butylated hydroxyanisole (BHA) is a synthetic phenolic compound consisting of a mixture of two isomeric organic compounds: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. We examined the effect of BHA against hydrogen peroxide (H2O2)-induced...
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Effects of Beta Hydroxy Acid on the Facial Skin in Acne Patients

Lee HS, Kim IH

  • KMID: 2303112
  • Korean J Dermatol.
  • 2002 Aug;40(8):886-889.
BACKGROUND: Several studies demonstrated that high concentration salicylic acid (beta hydroxy acid, BHA) peels were beneficial for acne, post inflammatory hyperpigmentation, melasma, oily skin, enlarged pores and surface roughness. OBJECTIVE: We...
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In vitro antioxidant properties of a ginseng intestinal metabolite IH-901

Lee NJ, Lee JW, Sung JH, Lee YJ, Kang JK

IH-901 (20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol or compound K) is a final intestinal bacterial metabolite of ginseng in humans. It has various pharmacologic effects such as antiaging, immunopotentiation, antistress, and antimetastatic activities. We analyzed...
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Antioxidative Activity of Lichen Thamnolia vermicularis in vitro

Luo H, Ren M, Lim KM, Koh YJ, Wang LS, Hur JS

This study was aimed at evaluating the antioxidant activities of methanol extract of Thamnolia vermicularis. The antioxidant activity, reducing power, superoxide anion radical scavenging and free radical scavenging activities were...
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Effect of p-Dimethylaminoazobenzene and 2(3)-tert-Butyl-4-hydroxyanisole on Lipid Pcroxidation, Glutathione-S-transferase, Peroxidase and Reductase in Rat Liver

Oh SH, Lee MH

An experiment was conducted in order to investigate the effect of p-dimethylaminoazobenzene (DAB) and 2(3)-tert-butyl-4-hydroxyanisole (BHA) on the lipid peroxidation and peroxide-destroying enzyme system in the rat liver. Dietary supplementation...
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The Early Result of Cementless Arthroplasty for Femur Neck Fracture in Elderly Patients with Severe Osteoporosis

Seo JS, Shin SK, Jun SH, Cho CH, Lim BH

PURPOSE: The purposes of the current study were to assess the early results of cementless hip arthroplasty (HA) for femoral neck fractures in elderly patients with severe osteoporosis and to...
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Effect of Advanced Glycation End Products on Rat Aortic Vascular Smooth Muscle Cells

Song JY, Ihm SH, Suh JY, Cho YJ, Yoo HJ, Park SW, Ihm JH

  • KMID: 2063383
  • J Korean Diabetes Assoc.
  • 2002 Apr;26(2):91-99.
BACKGROUND: Diabetes mellitus is an epidemiologically proven risk factor for atherosclerosis. Advanced glycation end products (AGE) have been implicated in the pathogenesis of many diabetic vascular complications. AGE not...
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Comparison of Minimally Invasive Total Hip Arthroplasty versus Conventional Hemiarthroplasty for Displaced Femoral Neck Fractures in Active Elderly Patients

Park KS, Oh CS, Yoon TR

Fractures of the femoral neck in elderly patients can be treated by internal fixation, hemiarthroplasty, or total hip arthroplasty (THA), and the treatment modality used should be determined on the...
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Hip Arthroplasty Using Collarless Polished Tapered Stem: Minimum 2 Years Follow-up Results

Sung YB, Choi JY, Oh SC

PURPOSE: This study evaluated the clinical and radiologic results of total hip arthroplasty and bipolar hemiarthroplasty using collarless polished tapered femoral stem. MATERIALS AND METHODS: We retrospectively reviewed the results of...
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Perioperative Comparison of Hip Arthroplasty Using the Direct Anterior Approach with the Posterolateral Approach

Lee SH, Kang SW, Jo S

PURPOSE: The aim of the current study is to report the advantage and disadvantage of total hip arthroplasty performed in direct anterior approach (DAA) by comparing it to the posterolateral...
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A Comparison of Internal Fixation and Bipolar Hemiarthroplasty for the Treatment of Reverse Oblique Intertrochanteric Femoral Fractures in Elderly Patients

Park BJ, Cho HM, Min WB

PURPOSE: To compare the clinical and radiological results between internal fixation using the proximal femoral nail system and bipolar hemiarthroplasty (BHA) in reverse oblique intertrochanteric hip fractures in elderly patients. MATERIALS...
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Influence of the Hippocampal Atrophy Extent on Secondary Generalized Tonic-Clonic Seizures in Temporal Lobe Epilepsy

Kim JS, Huh K, Kwon OY, Kim SY

  • KMID: 2066053
  • J Korean Neurol Assoc.
  • 1996 Mar;14(1):150-157.
Eventhough the hippocampal sclerosis (HS) is crucial in pathophysiology of temporal lobe epilepsy (TLE), the seizure semiology in relation to the extent of hippocampal atrophy(HA) has not been well addressed....
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Treatment of Unstable Intertrochanteric Fracture with Bipolar Hemiarthroplasty of Hip in Elderly Population: Short-term Results

Lee GW, Kwak JM, Chung SH

OBJECTIVES: The aim of this study is to evaluate the short-term results and complications of treating the intertrochanteric fracture with bipolar hemiarthroplasty (BHA) in elderly population. METHODS: We retrospectively reviewed 31...
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Bipolar Hip Arthroplasty vs. Total Hip Arthroplasty for Osteonecrosis of the Femoral Head

Kim SS, Sohn SK, Kim HJ, Sun SK

  • KMID: 2336221
  • J Korean Orthop Assoc.
  • 2010 Aug;45(4):273-280.
PURPOSE: To retrospectively compare surgical outcomes between bipolar hip arthroplasty and total hip arthroplasty in patients with osteonecrosis of the femoral head. MATERIALS AND METHODS: Between April 2000 and July 2004, we...
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