- Brain Tumor Stem Cells as Therapeutic Targets in Models of Glioma
-
Laks DR, Visnyei K, Kornblum H
- KMID: 1071412
- Yonsei Med J.
- 2010 Sep;51(5):633-640.
- doi: 10.3349/ymj.2010.51.5.633
At this time, brain tumor stem cells remain a controversial hypothesis while malignant brain tumors continue to present a dire prognosis of severe morbidity and mortality. Yet, brain tumor stem... -
- CITED
-
- Close
- SHARE
-
- Close
- 5' CpG island methylation of p16 is associated with absence of p16 expression in glioblastomas
-
Park SH, Jung KC, Ro JY, Kang GH, Khang SK
- KMID: 965879
- J Korean Med Sci.
- 2000 Oct;15(5):555-559.
- doi: 10.3346/jkms.2000.15.5.555
Recent evidence shows that transcriptional silencing as a consequence of hypermethylation of CpG islands is an important mechanism in the inactivation of p16INK4 tumor suppressor gene. This study is designed... -
- CITED
-
- Close
- SHARE
-
- Close
- Characterization of a brain tumor cell line established from transgenic mice expressing the vasopressin SV-40 T antigen
-
Kim SH, Kim MO, Lee SR, Kim KS, Lee TH, Lee HT, Ha JH, Kim TY, Ryoo ZY
- KMID: 1094144
- Exp Mol Med.
- 2006 Jun;38(3):196-202.
We previously reported that transgenic mice produced with a transgene consisting of the SV40 T antigen and vasopressin without the 3'-flanking region exhibit brain tumors and lymphoma. In this study,... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of p53 gene mutation in tumor aggressiveness of intracranial meningiomas
-
Cho H, Ha SY, Park SH, Park K, Chae YS
- KMID: 648081
- J Korean Med Sci.
- 1999 Apr;14(2):199-205.
- doi: 10.3346/jkms.1999.14.2.199
The mutations that occur in the p53 tumor suppressor gene have been studied in various human malignant tumors. However, little is known about this gene in meningiomas. To investigate the... -
- CITED
-
- Close
- SHARE
-
- Close
- The effect of isochromosome 17q presence, proliferative and apoptotic indices, expression of c-erbB-2, bcl-2 and p53 proteins on the prognosis of medulloblastoma
-
Nam DH, Wang KC, Kim YM, Chi JG, Kim SK, Cho BK
- KMID: 1730644
- J Korean Med Sci.
- 2000 Aug;15(4):452-456.
- doi: 10.3346/jkms.2000.15.4.452
Medulloblastoma accounts for 20 to 25+ACU- of all intracranial neoplasms in children. The significance of the presence of isochromosome 17q (i(17q)), proliferative potential, apoptotic activity, and expression of c-erbB-2, bd-2,... -
- CITED
-
- Close
- SHARE
-
- Close
- Preclinical studies for pharmacokinetics and biodistribution of Ad-stTRAIL, an adenovirus delivering secretable trimeric TRAIL for gene therapy
-
Kim CY, Park SH, Jeong M, Kwon OS, Doh H, Kang SH, Robbins PD, Kim BM, Seol DW, Kim BG
- KMID: 1123370
- Exp Mol Med.
- 2011 Oct;43(10):580-586.
- doi: 10.3858/emm.2011.43.10.065
Malignant glioma is the most frequent type in brain tumors. The prognosis of this tumor has not been significantly improved for the past decades and the average survival of patients... -
- CITED
-
- Close
- SHARE
-
- Close
