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Hard tissue regeneration using bone substitutes: an update on innovations in materials

Sarkar SK, Lee BT

Bone is a unique organ composed of mineralized hard tissue, unlike any other body part. The unique manner in which bone can constantly undergo self-remodeling has created interesting clinical approaches...
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The Effect of alpha MSH Analogues on Rat Bones

Lim SK, Li SZ, Rhee Y, Chung SS, Jin YJ, Yook JI

Melanocortin is the downstream mediator of leptin signaling and absence of leptin signaling in ob/ob and db/db mice revealed the enhancement of bone formation through the central regulation. While alpha-melanocyte-stimulating...
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Effects of Vitamin K2 on the Development of Osteopenia in Rats as the Models of Osteoporosis

Iwamoto J, Takeda T, Sato Y

Vitamin K2 is widely used for the treatment of osteoporosis in Japan. To understand the effects of vitamin K2 on bone mass and bone metabolism, we reviewed its effects on...
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Minocycline-induced Periarticular Black Bones in Inflamed Joints Which Underwent Arthroplastic Reconstruction

Yang S, Takakubo Y, Kobayashi , Asano T, Sasaki A, Sasaki K, Ohki H, Tamaki Y, Takagi M

BACKGROUND: Minocycline-induced pigmentation of bone (black bone) is well described in tooth-bearing intra-oral bone, but is less known in periarticular bone in patients who have undergone total joint arthroplasty. On...
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Marked Individual Variation in Isoflavone Metabolism After a Soy Challenge Can Modulate the Skeletal Effect of Isoflavones in Premenopausal Women

Kwak HS, Park SY, Kim MG, Yim CH, Yoon HK, Han KO

Soy-isoflavones may act as estrogenic agonists or antagonists depending on the endogenous hormone status. These clinical effects can be exerted variably in individuals by the metabolic ability to produce a...
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