- Use of stem-cell sheets expressing bone morphogenetic protein-7 in the management of a nonunion radial fracture in a Toy Poodle
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Song J, Kim Y, Kweon OK, Kang BJ
- KMID: 2398517
- J Vet Sci.
- 2017 Dec;18(4):555-558.
- doi: 10.4142/jvs.2017.18.4.555
A 12-year-old castrated Toy Poodle was referred to the Kangwon National University Animal Hospital with an oligotrophic nonunion fracture in the distal 1/3 of the left radius and an intact... -
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- Effect of combinatorial bone morphogenetic protein 2 and bone morphogenetic protein 7 gene delivery on osteoblastic differentiation
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Bae Y, Kim KH, Kim SH, Lee CW, Koo KT, Kim TI, Seol YJ, Ku Y, Rhyu IC, Chung CP, Lee YM
- KMID: 2321654
- J Korean Acad Periodontol.
- 2009 Aug;39(Suppl):279-286.
PURPOSE: Gene therapy (ex vivo) has recently been used as a means of delivering bone morphogenetic proteins (BMPs) to sites of tissue regeneration. In the present study, we investigated the... -
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- Carthamus tinctorius L. Increases BMP-2 Gene Expression during Bone Fracture Healing in Rats
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Lee KH, Sohn OJ, Ahn JC, Kim YW, Park SY, Kim JY
- KMID: 2285325
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):143-147.
Carthamus tinctorius L.is known to improve fracture healing, and bone morphogenetic proteins (BMPs) are associated with the formation and healing process of bone. BMP-2 and BMP-7 are two of the... -
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- Immunohistochemical Study of the Expression of Bone Morphogenetic Protein(BMP-7) Following Regenerative Periodontal Surgery
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Han KY, Cho SY, Lim KJ, Kim HJ, Park JC, Kim BO
- KMID: 2321546
- J Korean Acad Periodontol.
- 2000 Mar;30(1):51-63.
Extracellular matrix component is degraded by enzymes of thematrix metalloproteinases(MMPs). MMPs are produced by both hemopoietic and structural cells. Increased activity of MMP-3 in periodontium is strongly associated with inflammatory... -
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- Effects Of Chitosan On Human Osteoblasts
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Kim KH, Park YJ, Park JW, Lee YC, Cho BO, Ahn BK
- KMID: 1578321
- J Korean Assoc Oral Maxillofac Surg.
- 2002 Aug;28(4):280-285.
As the result of the study concerning "bone inducibility of chitosan", 1. "BMP-2"was observed mainly through the test when the "osteoblast"is exposed to the "chitosan". The expression of BMP-2 was 542.63... -
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- Spinal Fusion Based on Ex Vivo Gene Therapy Using Recombinant Human BMP Adenoviruses
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Kim GB, Kim JR, Ahn MH, Seo JS
- KMID: 2320138
- Yeungnam Univ J Med.
- 2007 Dec;24(2):262-274.
PURPOSE: Bone morphogenetic proteins (BMPs) play an important role in the formation of cartilage and bone, as well as regulating the growth of chondroblasts and osteoblasts. In this study, we... -
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- Bone-forming peptide-2 derived from BMP-7 enhances osteoblast differentiation from multipotent bone marrow stromal cells and bone formation
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Kim HK, Lee JS, Kim JH, Seon JK, Park KS, Jeong MH, Yoon TR
- KMID: 2382690
- Exp Mol Med.
- 2017 May;49(5):e328.
- doi: 10.1038/emm.2017.40
Strategies for efficient osteogenic differentiation and bone formation from stem cells would have clinical applications in treating nonunion fracture healing. Many researchers have attempted to develop adjuvants as specific stimulators... -
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- Effect of BMP-7 on the rat periodontal ligament cell
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Kim KH, Kim YJ, Chung HJ
- KMID: 1999758
- J Korean Acad Periodontol.
- 2005 Jun;35(2):289-298.
- doi: 10.5051/jkape.2005.35.2.289
Bone morphogenetic protein-7(BMP-7), a member of the transforming growth factor superfamily, stimulates osteoblast differentiation and bone formation. There are lots of evidences supporting a direct participation of periodontal ligament(PDL) cells... -
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- Bone Formation by rhBMP-7 Transduced HEK 293 Cells in Nude Mouse
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Jeong SY, Chang WT, Chang YS, Ahn MH, Kim JR, Song IH
- KMID: 2049759
- Yeungnam Univ J Med.
- 2003 Dec;20(2):142-151.
- doi: 10.12701/yujm.2003.20.2.142
To induce bone formation at ectopic site by tissue engineering and gene therapy, we transplanted collagen sponges containing rhBMP-7 transduced HEK 293 cells in the hypodermis of nude mice. Bone... -
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- Antifibrotic Effect of BMP-7 in the Peritoneum and the Mechanism
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Seo JY, Ha H, Yu MR, Kim JR, Ahn MW, Lee HB
- KMID: 2254128
- Korean J Nephrol.
- 2007 Jan;26(1):34-44.
PURPOSE: Bone morphogenic protein (BMP)-7, a member of TGF-beta1 superfamily, is an endogenous antifibrotic protein highly expressed in normal kidney. It is not known, however, whether human peritoneal mesothelial cells... -
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- The Effect of Adenoviral-mediated Gene Transfer of Bone Morphogenic Protein-7 on Peritoneal Fibrosis in an Animal Model of Peritoneal Dialysis
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Choi JY, Jin MK, Chun JH, Hyun SH, Choi HJ, Choi HJ, Cho JH, Kim MH, Ryu HM, Oh EJ, Choi SY, Kim CD, Kim YL, Park SH
- KMID: 2253224
- Korean J Nephrol.
- 2008 Jul;27(4):421-432.
PURPOSE: TGF-beta-induced epithelial-mesenchymal transition (EMT) is associated with peritoneal fibrosis during PD. We conducted this study to evaluate the effect of BMP-7 adenoviral gene transfer on the functional and structural... -
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- Morphological Study for Osteoinduction by Human Fibroblasts Transduced with rhBMP-7 Adenovirus
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Park JK, Sung EG, Kim JY, Kim JR, Ahn MH, Kim HT, Moon YS, Song IH
- KMID: 1937824
- Korean J Anat.
- 2006 Apr;39(2):129-138.
To evaluate availability of the BMP-7 adenovirus (AdBMP-7) as a gene therapy for osteoinduction, we investigated in morphological aspect at 1, 2, 4, 6 weeks after cells injection. Primary cultured... -
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- Osteogenesis of Recombinant BMP-7 Adenovirus-transduced Human Dermal Fibroblasts in Collagen Sponge
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Ryoo T, Kim JR, Ahn MW, Park JH, Sung HK, Kim JY, Sung EG, Lee Y, Song IH
- KMID: 2224498
- Korean J Anat.
- 2004 Aug;37(4):357-368.
As a preceding study to apply recombinant BMP-7 gene to the human, we investigated bone formation in immunodeficient mice by using tissue engineering and gene transplatation. Human dermal fibroblasts were... -
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- Frozen-thawed gelatin-induced osteogenic cell sheets of canine adipose-derived mesenchymal stromal cells improved fracture healing in canine model
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Yoon Y, Jung T, Afan Shahid M, Khan IU, Kim WH, Kweon OK
- KMID: 2464079
- J Vet Sci.
- 2019 Nov;20(6):e63.
- doi: 10.4142/jvs.2019.20.e63
We assessed the efficacy of frozen-thawed gelatin-induced osteogenic cell sheet (FT-GCS) compared to that of fresh gelatin-induced osteogenic cell sheet (F-GCS) with adipose-derived mesenchymal stromal cells (Ad-MSCs) used as the... -
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